Evalution of la positive cells in the canine lung transplantation

The rejection process related to Ia-positive cells consisting of the lymphocytes of bronchoalveolar lavage (BAL) was mainly evaluated at rejection of lung allotransplantation and also the inhibitory effect of CsA on occuring rejection is assessed. 1) In BAL taken from the transplanted lung, the increase in Ia positive rate and cell population was noted. Meanwhile in B-cells, activated T lymphocytes were remarkably increased in number. 2) The Ia positive rate in alveolar macrophages was the highest in the rejected lung. On the other hand in monocytes of the peripheral blood it was apparently reduced with statistical significance. 3) In virto study, the Ia positive rate of the lymphocytes in BAL was increased by PHA stimulation and significantly reduced by the addition of CsA. The Ia positive rate of macrophages in BAL also tended to be inhibited by adding CsA. The result enabled me to conclude that CsA acts as the elimination of Ia-positive rate in BAL lymphocytes and macrophages. 4) In the rejected lung a cluster of Ia-positive cells was seen not only around small vessels but in the alveolar space. Of interest is the fact that the role of Ia-positive cells is crucial to rejection of lung allografts

Simultaneous Combined Resection with Trachea, Bronchus and Aorta for Carcinoma of Thoracic Esophagus

Clinical experiences with combined sleeve resection of the trachea, bronchus and aorta with esophagectomy for esophageal cancer were reported in 6 cases including concurrent combined resection of the aorta and left main bronchus in one. 1) These cancers were advanced ones, showing nodal involvement of n2 in one, n3 in three and n4 in two. 2) In the three cases of combined resections of the aorta, it was made via left thoracotomy using preceding bypass with artificial vessel. There was no complication related to vascular surgery. 3) It must be prudent to determine the extent of the resection for involved trachea on the basis of an experience having recurrence at anastomosis. 4) It was sure that surgical outcome of combined resection was not necessarily satisfactory but improvement of it would be expected by avoiding early postoperative complication with meticulous postoperative care. 5) Based on our clinical experience with appearance of early lung metastasis following surgery, it is emphasized that potent multidisciplinary treatment is mandatory for improvement of the surgical result

Context-aware Service Composition and Change-over Using BPEL Engine and Semantic Web

Non

Verification of patient-setup accuracy using a surface imaging system with steep measurement angle

Purpose: We evaluate an SGRT device (Voxelan HEV-600 M/RMS) installed with Radixact, with the view angle of the Voxelan's camera at 74 degrees. The accuracy of Voxelan with this steep angle was evaluated with phantom experiments and inter-fractional setup errors of patients. Methods: In the phantom experiments, the difference between the measured values of Voxelan from the truth was evaluated for translations and rotations. The inter-fractional setup error between the setup using skin markers with laser localizer (laser setup: LS) and the setup using Voxelan (surface setup: SS) was compared for head and neck (N = 19), chest (N = 7) and pelvis (N = 9) cases. The inter-fractional setup error was calculated by subtracting from bone matching by megavoltage computed tomography (MVCT) as ground truth. Results: From the phantom experiments, the average difference between the measured values of Voxelan from the truth was within 1 mm and 1 degree. In all cases, inter-fractional setup error based on MVCT was not significantly different between LS and SS by Welch's t-test (P > 0.05). The vector offset of the LS for head and neck, chest, and pelvis were 6.5, 9.6, and 9.6 mm, respectively, and that of the SS were 5.8, 8.6, and 12.6 mm, respectively. Slight improvement was observed for the head and neck, and chest cases, however, pelvis cases were not improved because the umbilical region could not be clearly visualized as a reference. Conclusion: The results show that SS in Voxelan with an installation angle of 74 degrees is equal to or better than LS

Analyzing Effect of Edge Computing on Reducing Webpage Response Time

International audienceModern webpages consist of many rich objects dynamically produced by servers and client terminals at diverse locations, so we face an increase in web response time. To reduce the time, edge computing, in which dynamic objects are generated and delivered from edge nodes, is effective. For ISPs and CDN providers, it is desirable to estimate the effect of reducing the web response time when introducing edge computing. Therefore, in this paper, we derive a simple formula that estimates the lower bound of the reduction of the response time by modeling flows obtaining objects of webpages. We investigate the effect of edge computing in each webpage category, e.g., News and Sports, using data measured by browsing about 1,000 popular webpages from 12 locations in the world on PlanetLab