Исследование влияния термической обработки на вид излома ударных образцов и трещиностойкость сталей типа 06Г2МБТ

В работе исследованы образцы Шарпи низкоуглеродистых трубных сталей типа 06Г2МБТ после контролируемой прокатки и ускоренного охлаждения и термической обработки по различным режимам. На основе литературных данных и результатов собственных экспериментов проведен анализ поверхностей разрушения, изучено влияние температуры нагрева на уровень ударной вязкости стали и вид поверхности излома

Numerical study of QCD phase diagram at high temperature and density by a histogram method

We study the QCD phase structure at high temperature and density adopting a histogram method. Because the quark determinant is complex at finite density, the Monte-Carlo method cannot be applied directly. We use a reweighting method and try to solve the problems which arise in the reweighting method, i.e. the sign problem and the overlap problem. We discuss the chemical potential dependence of the probability distribution function in the heavy quark mass region and examine the applicability of the approach in the light quark region.Comment: 5 pages, 6 figures, presented at the International Conference "Critical Point and Onset of Deconfinement - CPOD 2011", Wuhan, November 7-11, 201

FABRICATION AND CHARACTERIZATION OF TITANIA-NANOSHEET FILM BY ELECTROPHORETIC DEPOSITION TECHNIQUE

Two-dimensional nanosheets, such as graphene and some oxides, have been investigated because of their unique functional properties. Titania is known as a key material showing a photocatalytic activity as well as a superhydrophilicity by irradiation of ultraviolet light. General preparation method for titania nanosheets has already been reported by Sasaki et al. in 1998.[1] On the other hand, an electrophoretic deposition (EPD) process of colloidal particles in a suspension has been used in various systems in order to create some functional materials and/or devices. In this work, we demonstrate a fabrication of film consisting of titania nanosheet by the simple EPD technique. Titania-nanosheet aqueous suspension was prepared according to the previous report [1]. Dried titania nanosheet powder was obtained to avoid electrolysis of water during EPD process. The dried titania nanosheet powder dispersed in acetone was used as the suspension for the EPD process. The EPD was carried out a constant d.c. voltage mode of 20 V for 300 s. An indium-tin oxide (ITO)-coated glass and a stainless steel plate was used as the anode and cathode, respectively. The two electrodes placed parallel to each other in the suspension. The distance of the electrodes was fixed at 5 mm. The deposition area was set to be 13 mm x 8 mm. The electrophoretically-deposited film was characterized by scanning electron microscope (SEM). Please click Additional Files below to see the full abstract

Deficit of Far-Infrared [CII] Line Emission toward the Galactic Center

We have observed the [CII] 158 micron line emission from the Galactic plane (-10 deg < l < 25 deg, |b| <= 3 deg) with the Balloon-borne Infrared Carbon Explorer (BICE). The observed longitudinal distribution of the [CII] line emission is clearly different from that of the far-infrared continuum emission; the Galactic center is not the dominant peak in the [CII] emission. Indeed, the ratio of the [CII] line emission to far-infrared continuum (I_[CII] / I_FIR) is systematically low within the central several hundred parsecs of the Galaxy. The observational results indicate that the abundance of the C+ ions themselves is low in the Galactic center. We attribute this low abundance mainly to soft UV radiation with fewer C-ionizing photons. This soft radiation field, together with the pervasively high molecular gas density, makes the molecular self-shielding more effective in the Galactic center. The self-shielding further reduces the abundance of C+ ions, and raises the temperature of molecular gas at the C+/C/CO transition zone.Comment: Compressed uuencoded postcript, 15 pages with 2 figures, to appear in the Astrophysical Journal (Letters

Astrometry of Water Maser Sources in Nearby Molecular Clouds with VERA - II. SVS 13 in NGC 1333

We report on the results of multi-epoch VLBI observations with VERA (VLBI Exploration of Radio Astrometry) of the 22 GHz H2O masers associated with the young stellar object SVS 13 in the NGC 1333 region. We have carried out phase-referencing VLBI astrometry and measured an annual parallax of the maser features in SVS 13 of 4.25+/-0.32 mas, corresponding to the distance of 235+/-18 pc from the Sun. Our result is consistent with a photometric distance of 220 pc previously reported. Even though the maser features were detectable only for 6 months, the present results provide the distance to NGC 1333 with much higher accuracy than photometric methods. The absolute positions and proper motions have been derived, revealing that the H2O masers with the LSR (local standard of rest) velocities of 7-8 km s-1 are most likely associated with VLA4A, which is a radio counterpart of SVS 13. The origin of the observed proper motions of the maser features are currently difficult to attribute to either the jet or the rotating circumstellar disk associated with VLA4A, which should be investigated through future high-resolution astrometric observations of VLA4A and other radio sources in NGC 1333.Comment: 9 pages, 5 figures. PASJ, in press (2008, Vol. 60, No. 1

Astrometry of Galactic Star Forming Region Sharpless 269 with VERA : Parallax Measurements and Constraint on Outer Rotation Curve

We have performed high-precision astrometry of H2O maser sources in Galactic star forming region Sharpless 269 (S269) with VERA. We have successfully detected a trigonometric parallax of 189+/-8 micro-arcsec, corresponding to the source distance of 5.28 +0.24/-0.22 kpc. This is the smallest parallax ever measured, and the first one detected beyond 5 kpc. The source distance as well as proper motions are used to constrain the outer rotation curve of the Galaxy, demonstrating that the difference of rotation velocities at the Sun and at S269 (which is 13.1 kpc away from the Galaxy's center) is less than 3%. This gives the strongest constraint on the flatness of the outer rotation curve and provides a direct confirmation on the existence of large amount of dark matter in the Galaxy's outer disk.Comment: 7 pages and 4 figures, Accepted by PASJ (Vol. 59, No. 5, October 25, 2007 issue

The apelin‑apelin receptor signaling pathway in fibroblasts is involved in tumor growth via p53 expression of cancer cells

Cancer-associated fibroblasts (CAFs) are pivotal in tumor progression. TP53-deficiency in cancer cells is associated with robust stromal activation. The apelin-apelin receptor (APJ) system has been implicated in suppressing fibroblast-to-myofibroblast transition in non-neoplastic organ fibrosis. The present study aimed to elucidate the oncogenic role of the apelin-APJ system in tumor fibroblasts. APJ expression and the effect of APJ suppression in fibroblasts were investigated for p53 status in cancer cells using human cell lines (TP53-wild colon cancer, HCT116, and Caco-2; TP53-mutant colon cancer, SW480, and DLD-1; and colon fibroblasts, CCD-18Co), resected human tissue samples of colorectal cancers, and immune-deficient nude mouse xenograft models. The role of exosomes collected by ultracentrifugation were also analyzed as mediators of p53 expression in cancer cells and APJ expression in fibroblasts. APJ expression in fibroblasts co-cultured with p53-suppressed colon cancer cells (HCT116sh p53 cells) was significantly lower than in control colon cancer cells (HCT116sh control cells). APJ-suppressed fibroblasts treated with an antagonist or small interfering RNA showed myofibroblast-like properties, including increased proliferation and migratory abilities, via accelerated phosphorylation of Sma- and Mad-related protein 2/3 (Smad2/3). In addition, xenografts of HCT116 cells with APJ-suppressed fibroblasts showed accelerated tumor growth. By contrast, apelin suppressed the upregulation of phosphorylated Smad2/3 in fibroblasts. MicroRNA 5703 enriched in exosomes derived from HCT116sh p53 cells inhibited APJ expression, and inhibition of miR-5703 diminished APJ suppression in fibroblasts caused by cancer cells. APJ suppression from a specific microRNA in cancer cell-derived exosomes induced CAF-like properties in fibroblasts. Thus, the APJ system in fibroblasts in the tumor microenvironment may be a promising therapeutic target.Saiki H., Hayashi Y., Yoshii S., et al. The apelin‑apelin receptor signaling pathway in fibroblasts is involved in tumor growth via p53 expression of cancer cells. International Journal of Oncology 63, 139 (2023); https://doi.org/10.3892/ijo.2023.5587