Age structural transition in South Africa

This chapter deals with the current age structure and the age structural transition (AST) underway in South Africa. We have used the national Census data for 1996 and 2001 and the Community survey data for 2007. In 2007, 31 percent of the population was enumerated below 15 years of age, 64 percent between 15- 64 and 5.4 percent 65+ implying the early stages of aging process. The median age in 2007 is 24.3 years, increased from 23 years in 1996. The proportion of young dependents is declining whereas that of the economically active and aged populations are increasing. Generally, the Black population appears younger and the Whites older. The other two ethnic groups are placed in the middle. This is, perhaps, a reflection of the differential fertility across the ethnic groups. The proportion of labour force population in 2007 is the highest for Asians & Indians followed by Whites; and the lowest for Blacks. So far as the proportion of the aged is concerned, Whites lead relatively high (12.4 %) as compared to coloured and Black population groups. During 1996-2007, the age structural transition for the total population is only marginal in South Africa. The median age of the total population grew from 23 years to 24.3 years, an increase of 5.6 percent. The female median age grew from 24.5 to 25.2 years, slightly better than that of males. The old age population has increased by 12.5 percent during the same period along with the global trend of female advantage. Again, the labour force population has increased by 5.5 percent. AST is highest for the white population, followed closely by Asians & Indians. This calls for continued higher investments in primary and secondary education, health care service delivery including reproductive health and social security. Again, for a country like South Africa where unemployment is quite high, the enormity of labour force (64%) has to be viewed seriously. Rapid employment generation, especially for the weaker groups, is the key. Further, one fifth (20.4 %) of the population is in the 15-24 years age group which is the target group for tertiary education. The slow process of AST among Black population warrants for preferential resource allocations especially in the areas of reproductive health and employment

Structural patterns of internal migration flows in Botswana: log-linear modeling approach

Abstract Among the total population in Botswana, 40 percent are lifetime migrants and females exceed males. Movement from rural to urban areas dominates the pattern of internal migration. The log-linear modeling analysis, which provides parametric values for the inter-district effects, shows that the Central district has the highest push effect and Gaborone, Northeast and Francistown are the most attractive places of destination. The other districts which pulled migrants from Central are Towns and small towns. Next, Southern and Kweneng districts have the highest push effects. Gaborone, the capital city district, exhibited a significantly high mobility in terms of both inmigration and outmigration. Again, Gaborone has the highest column effect or pull factor, followed closely by the Central district. The interaction effects between districts are also shown vividly through log-linear parameters

Chitinase and Fizz family members are a generalized feature of nematode infection with selective Upregulation of Ym1 and F10.1 by antigen-presenting cells

Ym1 and Fizz1 are secreted proteins that have been identified in a variety of Th2-mediated inflammatory settings. We originally found Ym1 and Fizz1 as highly expressed macrophage genes in a Brugia malayi infection model. Here, we show that their expression is a generalized feature of nematode infection and that they are induced at the site of infection with both the tissue nematode Litomosoides sigmodontis and the gastrointestinal nematode Nippostrongylus brasiliensis. At the sites of infection with N. brasiliensis, we also observed induction of other chitinase and Fizz family members (ChaFFs): acidic mammalian chitinase (AMCase) and Fizz2. The high expression of both Ym1 and AMCase in the lungs of infected mice suggests that abundant chitinase production is an important feature of Th2 immune responses in the lung. In addition to expression of ChaFFs in the tissues, Ym1 and Fizz1 expression was observed in the lymph nodes. Expression both in vitro and in vivo was restricted to antigen-presenting cells, with the highest expression in B cells and macrophages. ChaFFs may therefore be important effector or wound-repair molecules at the site of nematode infection, with potential regulatory roles for Ym1 and Fizz1 in the draining lymph nodes

The effect of increase in the number of fishing trips on the economic efficiency of 9.82 m and 11 m fishing trawlers along Kerala coast

Cost-benefit analysis of a 9.82 m and 11 m fishing trawlers based on the number of fishing trips is presented. The number of fishing trips per year determines the profit and loss of the trawler. With the increase in the number of fishing trips, the profit also increase for both the sizes of trawlers. The minimum quantity of prawn and fish to be landed for 0-20% profit for varying number of fishing trips are worked out. The break-even for 9.82 and 11m trawlers was observed to be 185 and 210 fishing trips respectively during 1980-81

Nonlinear magnetic response in ruthenocuprates

We have performed an investigation of the nonlinear magnetic response in ruthenocuprates. A negative, diverging-like peak at the main magnetic transition T_N in RuSr2RECu2O8 (RE = Gd, Y) indicates a possible canted antiferromagnetic order. Another well defined feature above T_N points to a blocking of superparamagnetic particles through the T^(-3) dependence of the third harmonic at higher temperatures. Below T_N a nondiverging peak appears, which is strongly affected by the addition of 10% of Cu ions in the RuO2 planes. In RuSr2RE(2-x)Ce(x)Cu2O10 the main magnetic transition T_M is accompanied by two characteristic temperatures in the third harmonic of the ac susceptibility, in agreement with recent studies from uSR and Mossbauer spectroscopy. We find that the spin-spin correlation temperature is the same in both families of ruthenocuprates.Comment: accepted for publication in EPJ

Hidden Symmetries and Integrable Hierarchy of the N=4 Supersymmetric Yang-Mills Equations

We describe an infinite-dimensional algebra of hidden symmetries of N=4 supersymmetric Yang-Mills (SYM) theory. Our derivation is based on a generalization of the supertwistor correspondence. Using the latter, we construct an infinite sequence of flows on the solution space of the N=4 SYM equations. The dependence of the SYM fields on the parameters along the flows can be recovered by solving the equations of the hierarchy. We embed the N=4 SYM equations in the infinite system of the hierarchy equations and show that this SYM hierarchy is associated with an infinite set of graded symmetries recursively generated from supertranslations. Presumably, the existence of such nonlocal symmetries underlies the observed integrable structures in quantum N=4 SYM theory.Comment: 24 page

Hypofractionated Radiotherapy for Stage I Squamous Cell Carcinoma Glottis: An Experience with 60Gy in 20 Fractions

Introduction: Early-stage glottic cancer has a high cure rate with definitive radiotherapy. Historical reports show excellent local control. The present study evaluated the outcomes of early glottic cancer patients treated with a hypofractionated radiotherapy schedule of 60Gy in 20 fractions.Material and Methods: This is a retrospective study of patients with stage I glottic cancer who received radical intent LINAC-based hypo-fractionated 3D conformal radiotherapy with a dose 60Gy in 20 fractions. The primary objective was to assess the locoregional control (LRC), and secondary objectives were to determine disease-free survival (DFS), overall survival (OS), and toxicity.Results: The analysis included 105 patients from the age range of 35-88 years. About 69% of patients were over 60 years of age. The median overall treatment time (OTT) was 26 days (24 – 30 days). The mean follow-up was 74 months, ranging from 9 to 135 months. Seven patients had locoregional recurrence after an initial complete clinical response. Six had local, and one had a regional nodal recurrence. DFS at five years and ten years were 83% and 69%, and OS at five years and ten years were 87% and 80%, respectively. Most patients reported grade I skin reactions and tolerated the treatment well. We did not observe any late adverse events such as persistent laryngeal edema or radiation necrosis.Conclusion: The radiotherapy schedule of 60Gy in 20 fractions over four weeks offers comparable local disease control with reasonable long-term side effects in T1 glottic cancer

HISTOPATHOLOGICAL AND IMMUNO-HISTOCHEMICAL EVALUATION OF MALE AND FEMALE REPRODUCTIVE SYSTEMS OF PORCINE CIRCOVIRUS-2 INFECTED PIGS

Porcine Circovirus-2 (PCV-2) is an emerging swine infection responsible for significant financial losses in the global swine industry. It has a significant negative impact on reproductive performance causing abortion, stillbirth, and other anomalies. As there is limited knowledge related to the histopathology of male and female reproductive systems in PCV-2 infected pigs, the current study was designed. Swine carcasses presented for post-mortem examination with a history of respiratory distress, anorexia, diarrhoea, wasting, and paleness of the skin collected from mid of 2021 to mid of 2022 from different parts of Kerala, India, were utilised in this study. The samples were initially screened with polymerase chain reaction (PCR) and were subjected to gross and histopathological studies. Out of 65 collected samples, 10 were positive for PCV-2 by PCR. The positive sample carcasses were emaciated, had poor body condition with visible bony prominences, decreased back fat thickness, rough, long hair coat, and sunken eyes. Mild oedema and congestion were seen in the testes, epididymis, and vas deferens of the male reproductive system and on accessory reproductive glands such as the bulbourethral gland, prostate gland, and seminal vesicle. In the female reproductive system, the ovary, oviduct, and uterus had mild congestion and oedema in most cases. Histopathology of the male reproductive system revealed mild degenerative changes, haemorrhage, and congestion in all cases. The vasa deferentia showed a loss of cilia in the pseudostratified columnar epithelium. The female reproductive organs had congestion, degenerative changes, and infiltration of mononuclear cells. For further confirmation, localisation of PCV-2 antigen was done in reproductive organs with immunohistochemistry (IHC). History, gross, histopathological findings, and PCR in combination with IHC highlight the pathologic effects of PCV-2 on reproductive organs in infected pigs

Application of DSTATCOM for surplus power circulation in MV and LV distribution networks with single-phase distributed energy resources

Single-phase distributed energy resources (DERs), such as rooftop photovoltaic arrays, are usually installed based on the need and affordability of clients without any regard to the power demand of the connected phase of a three-phase system. It might so happen that the power generation in a particular phase is more than its load demand. This may cause a reverse power flow in a particular phase, especially in a three-phase, four-wire distribution system. If now the load demand in the other two phases is more than their respective generations, then these two phases will see a forward power flow, while there will be a reverse power flow in the third phase. This will create severe unbalance in the upstream network. In this paper, a distribution static compensator (DSTATCOM) is used to circulate the excess generation from one phase to the others such that a set of balanced currents flow from or into the upstream network. Two different topologies of DSTATCOM are proposed in this paper for the low and medium voltage feeders. Two different power circulation strategies are developed for this purpose. Furthermore, a suitable feedback scheme is developed for each topology for power converter control. The performance of the proposed topologies and the control schemes for the DSTATCOM is evaluated through computer simulation studies using PSCAD/EMTDC

The genetic discrimination observatory : confronting novel issues in genetic discrimination

Genetic discrimination (GD) is the differential or unfair profiling of an individual on the basis of genetic data. This article summarizes the actions of the Genetic Discrimination Observatory (GDO) in addressing GD and recent developments in GD since late 2020. It shows how GD can take many forms in today’s rapidly evolving society.http://www.journals.elsevier.com/trends-in-geneticshj2022Immunolog