940 research outputs found

    CUSTOMER SATISFACTION TOWARDS HOSPITALS A STUDY ON SELECTED HOSPITALS AT SHIVAMOGGA CITY

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    CUSTOMER SATISFACTION TOWARDS HOSPITALS A STUDY ON SELECTED HOSPITALS AT SHIVAMOGGA CITY The opening of Indian economy since 1991 has given a new dimension to the economic structure of the country. The service sector is contributing more than 50% to the GDP. In service sector the contribution of healthcare sector towards GDP is significant.  India will spend a huge          Rs 200,000 crore on healthcare in the next five years as the country witnessing changes in its demographic profile accompanied with lifestyle diseases and increasing medical expenses. Nearly 80 per cent of the required investment is coming from the private sector. The government spending on healthcare is around 0.9 per cent of the total GDP, which limits the extent and effectiveness of the coverage it can provide. Private healthcare will continue to be the largest component in 2012 and is likely to double to    Rs 156,000 crore.  Therefore the study focuses on services provided by private hospitals.   Â

    A Mycobacterium smegmatis gyrase B specific monoclonal antibody reveals association of gyrase A and B subunits in the cell

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    DNA gyrase is a unique topoisomerase, which plays important roles in macromolecular events like DNA replication, transcription and genetic recombination. In this study a high affinity monoclonal antibody to the gyrase B (GyrB) subunit of Mycobacterium smegmatis was characterized, which did not cross-react with either the Escherichia coli GyrB subunit or with GyrB subunits from other mycobacterial species. The antibody recognized an epitope in the N-terminus, novobiocin-binding domain of GyrB. Immunoprecipitation of gyrase from M. smegmatis cell lysate revealed an association, mediated by ionic interactions, of gyrase A and GyrB subunits in the cell. This antibody is a valuable tool for structure-function analysis and immunocytological studies of mycobacterial DNA gyrase

    Mussel culture in mulky estuary, Dakshina Kannada district, Karnataka during 1997-'99

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    During 1997-'98 seasons, the mussel culture activities were carried out at Mulky estuary with the active participation of local fishermen and the growth rate was studied. Culture work was continued at two places in Mulky estuary during 1998-'99 seasons. The growth rate of mussels in Chitrapu area was higher than that observed in Mulky area. During 1998-'99 seasons, the meat content of the harvested mussel was low as they had spawned before the harvest. The culture works carried out at Mulky estuary reveal that mussel culture can be profitabily done during October-May months in Mulky estuary. The fishermen group can take up the culture activities as a part-time venture as the culture involves minimum labour only during the initial period and thereafter it needs little husbandry work. There is good demand for mussels in monsoon months when supply of marine fish is less due to ban on mechanized fishing. Mussels harvested in May can be processed and marketed for sale during the lean season, for which infrastructural facilities have to be developed. Once the marketing infrastructure is developed mussel culture activities can be taken up by more fishermen group in a profitable manner

    The Mn(II), Co(II), Ni(II) and Cu(II) complexes of (Z)-N'((1H-indol-3-yl)methylene)nicotinohydrazide Schiff base: synthesis, characterization and biological evaluation

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    Schiff bases being biological moieties possess diverse biological and pharmaceutical applications. Metal ions play an important role in various functions of the biological system as well as the human body. The importance of Schiff base and their metal complexes have been acknowledged in the field of bioinorganic chemistry. The current investigation hence focuses on the synthesis and characterization of a bidentate indole-based ligand(Z)-N'((1H-indol-3-yl)methylene)nicotinohydrazide (L) derived from indole-3-carboxaldehyde (1), nicotinic acid hydrazide (2) and their metal complexes of Mn(II), Co(II), Ni(II) and Cu(II), (4a-d) in 2:1 stichiometric ratio. All the synthesized ligand and complexes were characterized by IR, UV-Visible, H-1 NMR, C-13 NMR, Mass, Powder XRD analysis. Further, the ligand and their metal complexes were screened for antimicrobial, antioxidant and DNA cleavage studies. Among the synthesized complexes, Ni(II) (4c) showed highest antimicrobial activity against tested Gram -ve and Gram +ve bacterial strains and fungal microorganism, better than the ligand (L). The antioxidant activity results showed that the metal complexes (4a-d) were observed to be more active than the parent ligand. Furthermore, the ligand (L) and their respective metal (II) complexes (4a-d) were found to cleave the pBR322 DNA, during gel electrophoresis studies

    The role of the dermatologist in Raynaud’s phenomenon: a clinical challenge

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    Raynaud’s phenomenon (RP) is a functional vascular disorder involving extremities. In his practice, the dermatologist may frequently encounter RP which affects mainly women and is categorized into a primary benign form and a secondary form associated with different diseases (infections, drugs, autoimmune and vascular conditions, haematologic, rheumatologic and endocrinologic disorders). Still today, the differential diagnosis is a clinical challenge. Therefore, a careful history and a physical examination, together with laboratory tests and nailfold capillaroscopy, is mandatory. RP is generally benign, but a scheduled followâ up for primary RP patients should be established, due to risk of evolution to secondary RP. A combination of conservative measures and medications can help in the management of RP. The importance of avoiding all potential physical, chemical and emotional triggers, as well as quitting smoking, should be strongly suggested to the patient. As firstâ line treatment, dihydropyridine calcium channel blockers should be used. If this approach is not sufficient, prostacyclin derivatives, phosphodiesterases inhibitors and endothelin receptor antagonists can be considered as secondâ line treatment. In cases of acute ischaemia, nifedipine and intravenous prostanoids are helpful. In refractory cases, botulinum injections have shown a significant benefit. The approach to the RP patients requires therefore a coordinated care of specialists together with the primary care physician.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144681/1/jdv14914_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144681/2/jdv14914.pd

    Rural Load Management Using Information Technology

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    The mismatch between the generation and demand for electrical power is increasing at an alarming rate. This is mainly due shortage of conventional resources, use of appropriate technology for alternate energy sources and lack of awareness about energy conservation. Power supply to domestic, commercial and industrial consumers is a difficult task to the utilities controlled by the government. In rural India, irrigation pump sets are the major loads. The technical aptitude, attitude and co operation of the consumers helps a lot in energy management. The strategic power supply is affected if the consumers are not complying with the norms. A strategy is framed to provide power to domestic appliances around the clock and agricultural consumers on time division basis. But the local technicians play a corruptive role to violate this which is leading to overloading/failure of the distribution transformers frequently. Here, an attempt is made to devise a method to overcome the problem of agricultural consumers who are getting power on time division basis. A control unit is installed at each distribution station to automatically monitor and control the power supply to domestic and agricultural consumers as per the pre defined schedule. This paper explains the use of electronics and information technology in rural areas for better management of the power supply and consumption. The unauthorized connection leading to failure of distribution transformers is also taken care

    Diabetes mellitus and smoking among tuberculosis patients in a tertiary care centre in Karnataka, India

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    Supported by the TB Union/MSF Course on Operational Researc

    α-Fe2O3 Nanoparticles: An Efficient, Inexpensive Catalyst for the one-pot Preparation of 3,4-dihydropyrano[c]chromenes

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    This paper describes the combustion synthesis of α-Fe2O3 nanopowder at much lower temperature and its catalytic activity for the one-pot preparation of 3,4-dihydropyrano[c]chromenes. The combustion derived α-Fe2O3 nanopowder was characterized by powder X-ray diffraction (PXRD), Braunauer, Emmett and Teller (BET) surface area, scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). Highly efficient, three-component condensation of aromatic aldehyde, malanonitrile and 4-hydroxycoumarin catalyzed by α-Fe2O3 nanoparticles at room temperature is described. The method offers an excellent alternative to the synthesis of 3,4-dihydropyrano[c]chromenes. The reactions are rapid, clean, and the products with good yield and high purity
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