Peranan Sekuens Dixon Pada Pemeriksaan Mri Wrist Joint Tanpa Kontras Kasus Intraosseus Hemangioma

Magnetic Resonance   Imaging  (MRI)  is  a  medical  diagnostic  imaging  technique  that  works  on  the  principle  of  nuclear  magnetic  resonance.    MRI  aircraft  can  produce  internal  diagnostic  images  of human  needs  both  in sagittal, coronal,  and transverse  cuts  by not using  ionizing  radiation  (X-rays)  and also  not  using     radioactive  substances  but  based  on  the  principle of magnetic  resonance of hydrogen  atomic  nuclei   to reveal  anatomically  and  pathologically  to  establish  clinical  diagnoses,  one    of     which  is  Intraosseus  hemangioma  in  the  wrist  joint.  Intraosseous  hemangioma  is  classified  as   a   benign  tumor  of  a  vascular  nature.  The  use of dixon  sequences  is  proposed  for the assessment of   the  water  content    of   metaphysical  bone  marrow,  with  a  short  scan  time.    Dixon  sequence  imaging  can  be  used for suppression of fat in the  extremities,  but  also  for  quantification  of  fat  in  bones. The   research method  used  is  descriptive  research  with  an  observational  approach.  Data  collection  was  carried  out  from  November 7, 2022   to  February  7,     2023  using  a  3  Tesla  Mri  Siemens  Magnetom  Vida  aircraft.  The   patient sample  used  in  this  study  was  a  patient  with  complaints  of  the  wrist  joint.  Data  collection  is  carried  out  through  observation,  interviews  and  documentation Wrist  Joint  Examination  in  Intraosseus  Hemangioma  Cases  using  Siemens  Magnetom  Vida  3  Tesla  MRI  aircraft  has  an  examination  procedure  with  sequence  designs  Localizer_tra, Localizer_sag  +  cor+tra, t1_tse_tra_2mm, t2_tse_dixon_fs_cor_2mm, t2_tse_dixon_fs_sag_2mm   ,  t1_vibe_wo_cor_ iso,Pd_tse_fs_tra_2,   5_mm&nbsp

PERANAN SEQUENCE SWI (SUSCEPTIBILITY WEIGHTED IMAGING) PADA PEMERIKSAAN MRI BRAIN KLINIS PARKINSON

The Role of SWI (Susceptibility Weighted Imaging) Sequence in Clinical Parkinson’s MRI Brain Imaging. Magnetic Resonance Imaging (MRI) is a technique for imaging body crossings based on the principle of magnetic resonance of hydrogen atoms. Brain MRI examination aims to see anatomy and abnormalities within the brain to establish clinical diagnosis, pathological abnormalities, tumors, and surrounding abnormalities. Imaging examinations are also conducted to find other causes of Parkinsonism. Head MRI is one of the non-invasive examinations performed to help confirm the diagnosis of Parkinson's disease. This study aims to determine the procedure for Brain MRI examination with Parkinson's clinical and to determine the sequence information SWI (Susceptibility Weighted Imaging) can establish clinical diagnosis of Parkinson's. This study is qualitative descriptive with a case study approach. The subject consists of three patients with clinical Parkinson's. All subjects performed MRI brain 3 tesla examinations to determine the procedure and sequence information used. The research results were obtained according to the theory using an additional 2 mm sequence, while in the field using 0.9 mm sequence the examination was conducted using the head coil of the patient's position, namely supine, head first. Sequences used in field inspections are AAHead Scout, t1 fl2d transversal, t2 tse (time spin echo) dark fluid transversal, t2 tse (time spin echo)  transversal, ep2d diff (diffusion) 4scan trace, asl 3d transversal, tof cs carotids, flow pc3d MRV (magnetic resonance venography), tof brain MRA (magnetic resonance angiography), t2 swi (susceptibility weighted imaging) 3d transversal 0.9 mm. The thin axial sequence of 0.9 mm is more likely to see Parkinson's anatomical abnormalities, higher SNR and better spatial resolution than using a 2 mm slice thickness

Strategies to Apply Leadership Styles and Workloads to Hotel Employee’s Morale

Purpose: This research aims to determine the effect of leadership style and workload partially or simultaneously on employee’s morale at 4 star hotel in Kuta tourist area, southern part of Bali, Indonesia. Research methods: The samples used were 34 respondents using proportionate stratified random sampling techniques. The data collection methods are questionnaires that have been tested for validity and reliability in advance and the analysis technique used is the Classic Assumption Test, T test, F test, Multiple Linear Regression Analysis and Coefficient of Determination Analysis. Findings: The leadership style and workload variables have a significant positive partial effect on employee morale and the leadership style and workload variables have a significant positive effect simultaneously on employee morale. Implication: The influence of the leadership style is quite large in increasing hotel employee morale

The Strength of Authenticity in Developing Rural Tourism (A Case Study of Tri Eka Buana Village)

Purpose: This study aims to determine the strategies used in the authenticity of Tri Eka Buana Village, Bali, Indonesia, as a tourist attraction. Research methods: This research is a research mixed method with analytical techniques using the Internal Factor Analysis (IFAS), External Factor Analysis (EFAS), Internal-External Matrix (IE), SWOT, and Quantitative Strategic Planning Matrix (QSPM) Analysis. Findings: Based on the results of the IFAS matrix analysis, the main strength is that it has beautiful natural and artificial potential such as Bukit Abah, Danu Seliwah Temple, Dukuh Sakti Waterfall, Umananing Malini dance and Balinese Arak that can attract tourists, while the main weakness is that access to tourist objects is inadequate, such as a narrow and irregular parking area. Based on the results of the EFAS matrix analysis, it is known that the main opportunity is the development of Tri Eka Buana Village by involving local communities so as to minimize unemployment, preserve cultural and natural traditions while the main threat faced is competition between other tourism objects that have developed. The results of the IE Matrix research place the village in theposition Growth (Cell I). Implication: SWOT analysis resulted in 8 alternative strategies of authenticity from the 8 strategies, 3 priority strategies were obtained and have been calculated through the QSPM Matrix with a total TAS of 194.13, 193.57, and 186.46, namely optimizing the potential promotion of Tri Eka Buana Village Karangasem Bali through the media. social media such as Instagram, Facebook, and websites

Selecting Green Supplier for Perishable Raw Materials using AHP Method at Nunia Boutique Villa Seminyak

Purpose: The aim of this research is to do the selection for green supplier for perishable raw material at Nunia Boutique Villa, Villa with 8 Units Villa located at Seminyak Badung Bali. Research methods: One of the methods that used in this research is Analytical Hierarchy Process (AHP) method with Vendor Performance Index (VPI) is a Quality, Cost, Delivery, Flexibility, and Responsiveness (QCDFR) by adding the Environment Management criteria. This research used the AHP method with the expert choice software. Findings: The final rating of relative importance’s supplier selection criteria was found: the Quality criteria (0.472) was ranked first in the order of priority in the green supplier selection criteria. Implication: The Cost criteria with 0.192, Environment Management criteria (0.102), Delivery criteria (0.091), Flexibility criteria (0.076) and the last criterion is Responsiveness (0.067)

Human Resources Efforts to Improve Employees Performance at JW Marriott Surabaya

Purpose: Human resources are the first elements of an organization. This study aims to find out and analyze the efforts made by the Human Resouces department in improving the employees performance of JW Marriott Surabaya. Research methods: Data collection techniques by using of observation, interviews, documentation, and studies literature. Data analysis in this study using qualitative method with technical tringulation analysis. Findings: The results showed that performance improvement efforts began with employee selection, employee placement, training and development, discipline in employee attendance, and the provision of salaries and compensation to employees but the need for supervision, multiplying variants of methods in training, and acting decisively to employees who are less disciplined to existing regulations. Implications: This research was conducted to Human Resources which is considered to know the efforts to improv-ing employees performance

Analysis of Work Skills and Work Discipline in Improving Hotel Employee Performance

Purpose: This study aims to determine the influence of work skills and work disciplines both partially and simultane-ously on the performance of employees of Kayumanis Jimbaran Private Estate & Spa and to find out the most dominant variables between work skills and work disciplines in affecting employee performance at Kayumanis Jimbaran Private Estate & Spa. Research methods: The population of this study is the entire employees of Kayumanis Jimbaran Private Estate & Spa which amounts to 83 people.  Data collection techniques in this study are through interviews, observations, ques-tionnaires and literature studies. Data analysis using quantitative analysis of primary data processed using multiple regression analysis using SPSS 25.0 program. Findings: The results of this study show that there is a partial and simultaneous influence of variable work skills and work disciplines on employee performance. The coefficient of determination shows a value of 0.754 which means that Work Skills and Disciplines contributed in influencing Employee Performance by 75.4% and the remaining 24.6% was influenced by other factors not studied. Implications: While the effective contribution shows the variable Work Skills have a greater influence on Employee Perfor-mance compared to Work Discipline of 45.44%

Review xanthan gum: produksi dari substrat biomassa, variabel efektif, karakteristik dan regulasi serta aplikasi dan potensi pasar

Xanthan gum is an extracellular polysaccharide produced by a pure culture of Xanthomonas campestris through the fermentation process of carbohydrate sources in controlled conditions. These conditions must be carefully evaluated to obtain an optimal combination between yield and quality of the gum, and also production costs. The issue of this review is to provide a consolidated source of information on studies about xanthan gum production, alternative carbon sources from biomass substrates, effective variables on optimization production, characteristics, applications, and regulations status of xanthan gum. Lastly, the market potential is also discussed in this review

Newly diagnosed rheumatic heart disease among indigenous populations in the Pacific

Objectives Rheumatic heart disease (RHD) remains the leading acquired heart disease in the young worldwide. We aimed at assessing outcomes and influencing factors in the contemporary era. Methods Hospital-based cohort in a high-income island nation where RHD remains endemic and the population is captive. All patients admitted with newly diagnosed RHD according to World Heart Federation echocardiographic criteria were enrolled (2005–2013). The incidence of major cardiovascular events (MACEs) including heart failure, peripheral embolism, stroke, heart valve intervention and cardiovascular death was calculated, and their determinants identified. Results Of the 396 patients, 43.9% were male with median age 18 years (IQR 10–40)). 127 (32.1%) patients presented with mild, 131 (33.1%) with moderate and 138 (34.8%) with severe heart valve disease. 205 (51.8%) had features of acute rheumatic fever. 106 (26.8%) presented with at least one MACE. Among the remaining 290 patients, after a median follow-up period of 4.08 (95% CI 1.84 to 6.84) years, 7 patients (2.4%) died and 62 (21.4%) had a first MACE. The annual incidence of first MACE and of heart failure were 59.05‰ (95% CI 44.35 to 73.75) and 29.06‰ (95% CI 19.29 to 38.82), respectively. The severity of RHD at diagnosis (moderate vs mild HR 3.39 (0.95 to 12.12); severe vs mild RHD HR 10.81 (3.11 to 37.62), p<0.001) and ongoing secondary prophylaxis at follow-up (HR 0.27 (0.12 to 0.63), p=0.01) were the two most influential factors associated with MACE. Conclusions Newly diagnosed RHD is associated with poor outcomes, mainly in patients with moderate or severe valve disease and no secondary prophylaxis

Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: implications for calcification-related chronic inflammatory diseases

Calcification-related chronic inflammatory diseases are multifactorial pathological processes, involving a complex interplay between inflammation and calcification events in a positive feed-back loop driving disease progression. Gla-rich protein (GRP) is a vitamin K dependent protein (VKDP) shown to function as a calcification inhibitor in cardiovascular and articular tissues, and proposed as an anti-inflammatory agent in chondrocytes and synoviocytes, acting as a new crosstalk factor between these two interconnected events in osteoarthritis. However, a possible function of GRP in the immune system has never been studied. Here we focused our investigation in the involvement of GRP in the cell inflammatory response mechanisms, using a combination of freshly isolated human leucocytes and undifferentiated/differentiated THP-1 cell line. Our results demonstrate that VKDPs such as GRP and matrix gla protein (MGP) are synthesized and gamma-carboxylated in the majority of human immune system cells either involved in innate or adaptive immune responses. Stimulation of THP-1 monocytes/macrophages with LPS or hydroxyapatite (HA) up-regulated GRP expression, and treatments with GRP or GRP-coated basic calcium phosphate crystals resulted in the down-regulation of mediators of inflammation and inflammatory cytokines, independently of the protein gamma-carboxylation status. Moreover, overexpression of GRP in THP-1 cells rescued the inflammation induced by LPS and HA, by down-regulation of the proinflammatory cytokines TNF alpha, IL-1 beta and NFkB. Interestingly, GRP was detected at protein and mRNA levels in extracellular vesicles released by macrophages, which may act as vehicles for extracellular trafficking and release. Our data indicate GRP as an endogenous mediator of inflammatory responses acting as an anti-inflammatory agent in monocytes/macrophages. We propose that in a context of chronic inflammation and calcification-related pathologies, GRP might act as a novel molecular mediator linking inflammation and calcification events, with potential therapeutic application.Portuguese Science and Technology Foundation (FCT) [PTDC/SAU-ORG/117266/2010, PTDC/BIM-MEC/1168/2012, UID/Multi/ 04326/2013]; FCT fellowships [SFRH/BPD/70277/2010, SFRH/BD/111824/2015