The non-Abelian Debye screening length beyond leading order

In quantum electrodynamics, static electric fields are screened at non-zero temperatures by charges in the plasma. The inverse screening length, or Debye mass, may be analyzed in perturbation theory and is of order $eT$ at relativistic temperatures. An analogous situation occurs when non-Abelian gauge theories are studied perturbatively, but the perturbative analysis breaks down when corrections of order $e^2 T$ are considered. At this order, the Debye mass depends on the non-perturbative physics of confinement, and a perturbative ``definition'' of the Debye mass as the pole of a gluon propagator does not even make sense. In this work, we show how the Debye mass can be defined non-perturbatively in a manifestly gauge invariant manner (in vector-like gauge theories with zero chemical potential). In addition, we show how the $O(e^2 T)$ correction could be determined by a fairly simple, three-dimensional, numerical lattice calculation of the perimeter-law behavior of large, adjoint-charge Wilson loops.Comment: 30 pages, revtex format, 9 postscript figures included using epsf.st

Two-point functions for SU(3) Polyakov Loops near T_c

We discuss the behavior of two point functions for Polyakov loops in a SU(3) gauge theory about the critical temperature, T_c. From a Z(3) model, in mean field theory we obtain a prediction for the ratio of masses at T_c, extracted from correlation functions for the imaginary and real parts of the Polyakov loop. This ratio is m_i/m_r = 3 if the potential only includes terms up to quartic order in the Polyakov loop; its value changes as pentic and hexatic interactions become important. The Polyakov Loop Model then predicts how m_i/m_r changes above T_c.Comment: 5 pages, no figures; reference adde

Cytomorphological Studies on Stem of Luffa echinata Roxb

Luffa echinata Roxb., commonly known as Bindal in Hindi is used for its hypoglycemic activity in the indigenous system of medicine. No pharmacognostical study on stem is reported in the literature till date; therefore, it was decided to study macroscopical and cytomorphological characters in detail to bring out salient diagnostic features. The stem pieces available in the market are 1.5–17 cm long and 5–8 mm in diameter, showing yellowish-brown to brownish-black surface with longitudinal furrows, fracture is fibrous, and taste is bitter. Mature stem shows single-layered epidermis, seven layers of collenchyma below five ridges but one to two layers of parenchyma in rest of the region beneath the epidermis, continuous wide wavy layer of pericycle composed of three to eight layers of fiber. There are five conjoint bi-collateral open vascular bundles one below each ridge and additional four medullary vascular bundles in the pith each facing furrows

The future of social is personal: the potential of the personal data store

This chapter argues that technical architectures that facilitate the longitudinal, decentralised and individual-centric personal collection and curation of data will be an important, but partial, response to the pressing problem of the autonomy of the data subject, and the asymmetry of power between the subject and large scale service providers/data consumers. Towards framing the scope and role of such Personal Data Stores (PDSes), the legalistic notion of personal data is examined, and it is argued that a more inclusive, intuitive notion expresses more accurately what individuals require in order to preserve their autonomy in a data-driven world of large aggregators. Six challenges towards realising the PDS vision are set out: the requirement to store data for long periods; the difficulties of managing data for individuals; the need to reconsider the regulatory basis for third-party access to data; the need to comply with international data handling standards; the need to integrate privacy-enhancing technologies; and the need to future-proof data gathering against the evolution of social norms. The open experimental PDS platform INDX is introduced and described, as a means of beginning to address at least some of these six challenges

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4 (62.3 (55.1�70.8) million) to 6.4 (58.3 (47.6�70.7) million), but is predicted to remain above the World Health Organization�s Global Nutrition Target of <5 in over half of LMICs by 2025. Prevalence of overweight increased from 5.2 (30 (22.8�38.5) million) in 2000 to 6.0 (55.5 (44.8�67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic. © 2020, The Author(s)

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)

An amendment to this paper has been published and can be accessed via a link at the top of the paper. © 2020, The Author(s)