Feasibility of abdominoplasty with Cesarean section

Abdominoplasty is an esthetic surgical procedure that restores abdominal contouring. Repeated pregnancies combined with advancing maternal age usually lead to lower abdominal skin redundancy and excess fat accumulation. Delivery via Cesarean section adds weakness to the lower abdominal wall muscles and yields a lower transverse Cesarean scar. Some patients request whether abdominoplasty can be performed with Cesarean section in the same setting, to avoid a future surgery. This study was designed to evaluate the outcome of combined abdominoplasty with Cesarean section. The study included 50 pregnant women from September 2009 to June 2010 with an average follow-up period of 9 months. Nine patients (18%) developed wound infection; three of them (6%) developed wound dehiscence. Six patients (12%) developed lower abdominal skin necrosis; three of them (6%) were treated conservatively and healed by secondary intention, while surgical debridement and secondary sutures were needed in the other three patients (6%). Residual abdominal skin redundancy in nine patients (18%), outward bulging of the abdomen and lack of waist definition in 16 patients (32%), and outward bulging of the umbilicus in twelve patients (24%) were the reported unesthetic results. The results were compared with results of 80 abdominoplasties in nonpregnant women

A Comparative Study of Social Enterprises: North vs. South Perspectives

Social entrepreneurship as a practice that integrates economic and social value creation has a strong global presence. This chapter capitalizes on the evolution of the concept of social enterprise in the Western literature to analyze its manifestation in the Middle East and North Africa (MENA) region. Specifically, using empirical evidence from seven Arab countries, this chapter documents the understanding and application of social enterprises in the MENA region. Through the voices of social entrepreneurs who are working across the MENA countries, we document how social enterprise is displayed in practice along with both the constraints and the opportunities facing social entrepreneurs across this region. This new context-specific approach is then used to shed light on the similarities and differences of social enterprise practices across the international scene and the MENA region. The findings presented highlight the uniqueness of social enterprise in the MENA context, combining elements of both European and American approaches, in addition to some context-specific features

Genome wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability

International audienceGenomic copy number variants (CNVs) are routinely identified and reported back to patients with neuropsychiatric disorders, but their quantitative effects on essential traits such as cognitive ability are poorly documented. We have recently shown that the effect size of deletions on cognitive ability can be statistically predicted using measures of intolerance to haploinsufficiency. However, the effect sizes of duplications remain unknown. It is also unknown if the effect of multigenic CNVs are driven by a few genes intolerant to haploinsufficiency or distributed across tolerant genes as well. Here, we identified all CNVs > 50 kilobases in 24,092 individuals from unselected and autism cohorts with assessments of general intelligence. Statistical models used measures of intolerance to haploinsufficiency of genes included in CNVs to predict their effect size on intelligence. Intolerant genes decrease general intelligence by 0.8 and 2.6 points of intelligence quotient when duplicated or deleted, respectively. Effect sizes showed no heterogeneity across cohorts. Validation analyses demonstrated that models could predict CNV effect sizes with 78% accuracy. Data on the inheritance of 27,766 CNVs showed that deletions and duplications with the same effect size on intelligence occur de novo at the same frequency. We estimated that around 10,000 intolerant and tolerant genes negatively affect intelligence when deleted, and less than 2% have large effect sizes. Genes encompassed in CNVs were not enriched in any GOterms but gene regulation and brain expression were GOterms overrepresented in the intolerant subgroup. Such pervasive effects on cognition may be related to emergent properties of the genome not restricted to a limited number of biological pathways

Measurement of the CP-violating phase ϕs in B0s→J/ψϕ decays in ATLAS at 13 TeV

A measurement of the B0s→J/ψϕ decay parameters using 80.5fb−1 of integrated luminosity collected with the ATLAS detector from 13 TeV proton–proton collisions at the LHC is presented. The measured parameters include the CP-violating phase ϕs, the width difference ΔΓs between the B0s meson mass eigenstates and the average decay width Γs. The values measured for the physical parameters are combined with those from 19.2fb−1 of 7 and 8 TeV data, leading to the following: ϕs=−0.087±0.036 (stat.)±0.021 (syst.) rad ΔΓs=0.0657±0.0043 (stat.)±0.0037 (syst.) ps−1 Γs=0.6703±0.0014 (stat.)±0.0018 (syst.) ps−1 Results for ϕs and ΔΓs are also presented as 68% confidence level contours in the ϕs–ΔΓs plane. Furthermore the transversity amplitudes and corresponding strong phases are measured. ϕs and ΔΓs measurements are in agreement with the Standard Model predictions.publishedVersio

Search for new phenomena with top quark pairs in final states with one lepton, jets, and missing transverse momentum in pp collisions at √s = 13 TeV with the ATLAS detector

A search for new phenomena with top quark pairs in final states with one isolated electron or muon, multiple jets, and large missing transverse momentum is performed. Signal regions are designed to search for two-, three-, and four-body decays of the directly pair-produced supersymmetric partner of the top quark (stop). Additional signal regions are designed specifically to search for spin-0 mediators that are produced in association with a pair of top quarks and decay into a pair of dark-matter particles. The search is performed using the Large Hadron Collider proton-proton collision dataset at a centre-of-mass energy of √s = 13 TeV recorded by the ATLAS detector from 2015 to 2018, corresponding to an integrated luminosity of 139 fb−1. No significant excess above the Standard Model background is observed, and limits at 95% confidence level are set in the stop-neutralino mass plane and as a function of the mediator mass or the dark-matter particle mass. Stops are excluded up to 1200 GeV (710 GeV) in the two-body (three-body) decay scenario. In the four-body scenario stops up to 640 GeV are excluded for a stop-neutralino mass difference of 60 GeV. Scalar and pseudoscalar dark-matter mediators are excluded up to 200 GeV when the coupling strengths of the mediator to Standard Model and dark-matter particles are both equal to one and when the mass of the dark-matter particle is 1 GeV.publishedVersio

Search for supersymmetry in events with four or more charged leptons in 139 fb−1 of √s= 13 TeV pp collisions with the ATLAS detector

A search for supersymmetry in events with four or more charged leptons (electrons, muons and τ-leptons) is presented. The analysis uses a data sample corresponding to 139 fb−1 of proton-proton collisions delivered by the Large Hadron Collider at √s = 13 TeV and recorded by the ATLAS detector. Four-lepton signal regions with up to two hadronically decaying τ-leptons are designed to target several supersymmetric models, while a general five-lepton signal region targets any new physics phenomena leading to a final state with five charged leptons. Data yields are consistent with Standard Model expectations and results are used to set upper limits on contributions from processes beyond the Standard Model. Exclusion limits are set at the 95% confidence level in simplified models of general gauge-mediated supersymmetry, excluding higgsino masses up to 540 GeV. In R-parity-violating simplified models with decays of the lightest supersymmetric particle to charged leptons, lower limits of 1.6 TeV, 1.2 TeV, and 2.5 TeV are placed on wino, slepton and gluino masses, respectively.publishedVersio

Measurement of light-by-light scattering and search for axion-like particles with 2.2 nb^−1 of Pb+Pb data with the ATLAS detector

This paper describes a measurement of light-by-light scattering based on Pb+Pb collision data recorded by the ATLAS experiment during Run 2 of the LHC. The study uses 2.2 nb−1 of integrated luminosity collected in 2015 and 2018 at √sNN = 5.02 TeV. Light-by-light scattering candidates are selected in events with two photons produced exclusively, each with transverse energy EγT > 2.5 GeV, pseudorapidity |ηγ| 5 GeV, and with small diphoton transverse momentum and diphoton acoplanarity. The integrated and differential fiducial cross sections are measured and compared with theoretical predictions. The diphoton invariant mass distribution is used to set limits on the production of axion-like particles. This result provides the most stringent limits to date on axion-like particle production for masses in the range 6–100 GeV. Cross sections above 2 to 70 nb are excluded at the 95% CL in that mass interval.publishedVersio

Search for pair production of third-generation scalar leptoquarks decaying into a top quark and a τ-lepton in pp collisions at √s = 13 TeV with the ATLAS detector

A search for pair production of third-generation scalar leptoquarks decaying into a top quark and a τ-lepton is presented. The search is based on a dataset of pp collisions at √s = 13 TeV recorded with the ATLAS detector during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 139 fb−1. Events are selected if they have one light lepton (electron or muon) and at least one hadronically decaying τ -lepton, or at least two light leptons. In addition, two or more jets, at least one of which must be identified as containing b-hadrons, are required. Six final states, defined by the multiplicity and flavour of lepton candidates, are considered in the analysis. Each of them is split into multiple event categories to simultaneously search for the signal and constrain several leading backgrounds. The signal-rich event categories require at least one hadronically decaying τ-lepton candidate and exploit the presence of energetic final-state objects, which is characteristic of signal events. No significant excess above the Standard Model expectation is observed in any of the considered event categories, and 95% CL upper limits are set on the production cross section as a function of the leptoquark mass, for different assumptions about the branching fractions into tτ and bν. Scalar leptoquarks decaying exclusively into tτ are excluded up to masses of 1.43 TeV while, for a branching fraction of 50% into tτ, the lower mass limit is 1.22 TeV.publishedVersio

A search for the decays of stopped long-lived particles at √s = 13 TeV with the ATLAS detector

A search for long-lived particles, which have come to rest within the ATLAS detector, is presented. The subsequent decays of these particles can produce high-momentum jets, resulting in large out-of-time energy deposits in the ATLAS calorimeters. These de- cays are detected using data collected during periods in the LHC bunch structure when collisions are absent. The analysed dataset is composed of events from proton-proton collisions produced by the Large Hadron Collider at a centre-of-mass energy of s√ = 13 TeV and recorded by the ATLAS experiment during 2017 and 2018. The dataset used for this search corresponds to a total live time of 579 hours. The results of this search are used to derive lower limits on the mass of gluino R-hadrons, assuming a branching fraction B(g∼→qq¯¯χ01) = 100%, with masses of up to 1.4 TeV excluded for gluino lifetimes of 10−5 to 103 s.publishedVersio