Sharp bounds and normalization of Wiener-type indices

10.1371/journal.pone.0078448PLoS ONE811-POLN

Greedy Trees, Caterpillars, and Wiener-type Graph Invariants

NatuurwetenskappeWiskundePlease help us populate SUNScholar with the post print version of this article. It can be e-mailed to: [email protected]

Synthesis and binding properties of guanidinium biscarboxylates

The ammonium ion binding site of the enzyme glutaminase HisF inspired us to design guanidinium biscarboxylates as potential self-organized ionophores in molecular recognition. The syntheses of the title compounds based on aliphatic and aromatic building blocks, along with a general method for the preparation of δ-aminoethoxyacetic acids, are presented in this work. Investigation of the binding properties of the title compounds in dimethyl sulfoxide (DMSO) and methanol solution revealed no ammonium ion affinity, but interaction of the guanidinium moiety with acetate ions