War and the Reelection Motive: Examining the Effect of Term Limits

This article investigates the relationship between term limits and international conflict. Theories of political survival and diversionary war both imply term limits should play a role in international relations, whereas “permanent referendum theory,” largely motivated by work in American politics, suggests otherwise. Drawing on these theories, we formulate and test competing hypotheses regarding term limits and international crises. Using dyadic militarized interstate disputes data and information on forty-eight democracies with term limits, we uncover strong evidence to support the claim that leaders reaching final terms in office are more likely to initiate conflict than those still subject to reelection. Moreover, we find that the likelihood of conflict initiation is significantly higher during times of recession, but only in the absence of binding term limits. While binding electoral terms and economic downturns are both independently associated with increased levels of conflict initiation, in concert their conditional effects actually counteract each other

Once is an Instance, Twice is a Hobby: Multiple Optical and Near-Infrared Changing-Look Events in NGC 5273

NGC 5273 is a known optical and X-ray variable AGN. We analyze new and archival IR, optical, UV, and X-ray data in order to characterize its long-term variability from 2000 to 2022. At least one changing-look event occurred between 2011 and 2014, when the AGN changed from a Type 1.8/1.9 Seyfert to a Type 1. It then faded considerably at all wavelengths, followed by a dramatic but slow increase in UV/optical brightness between 2021 and 2022. We propose that NGC 5273 underwent multiple changing-look events between 2000 and 2022 -- starting as a Type 1.8/1.9, NGC 5273 changes-look to a Type 1 only temporarily in 2002 and again in 2014, reverting back to a Type 1.8/1.9 by 2005 and 2017, respectively. In 2022, it is again a Type 1 Seyfert with optical and NIR broad emission lines. We characterize the changing-look events and their connection to the dynamic accretion and radiative processes in NGC 5273.Comment: 18 pages, 13 figures, 4 tables, submitting to MNRA

Discovery and Follow-up of ASASSN-19dj: An X-ray and UV Luminous TDE in an Extreme Post-Starburst Galaxy

We present observations of ASASSN-19dj, a nearby tidal disruption event (TDE) discovered in the post-starburst galaxy KUG 0810+227 by the All-Sky Automated Survey for Supernovae (ASAS-SN) at a distance of d $\simeq$ 98 Mpc. We observed ASASSN-19dj from $-$21 to 392 days relative to peak UV/optical emission using high-cadence, multi-wavelength spectroscopy and photometry. From the ASAS-SN $g$-band data, we determine that the TDE began to brighten on 2019 February 6.8 and for the first 25 days the rise was consistent with a flux $\propto$ $t^2$ power-law. ASASSN-19dj peaked in the UV/optical on 2019 March 6.5 (MJD = 58548.5) at a bolometric luminosity of $L = (6.2 \pm 0.2) \times 10^{44} \text{ erg s}^{-1}$. Initially remaining roughly constant in X-rays and slowly fading in the UV/optical, the X-ray flux increased by over an order of magnitude $\sim$225 days after peak, resulting from the expansion of the X-ray emitting surface. The late-time X-ray emission is well-fit by a blackbody with an effective radius of $\sim 1 \times 10^{12} \text{ cm}$ and a temperature of $\sim 6 \times 10^{5} \text{ K}$. Analysis of Catalina Real-Time Transient Survey images reveals a nuclear outburst roughly 14.5 years earlier with a smooth decline and a luminosity of $L_V$ $\geq$ $1.4 \times 10^{43}$ erg s$^{-1}$, although the nature of the flare is unknown. ASASSN-19dj occurred in the most extreme post-starburst galaxy yet to host a TDE, with Lick H$\delta_{A}$ = $7.67 \pm 0.17$ \AA.Comment: 25 pages, 14 figures. Will be submitted to MNRAS. For a short video description please see https://youtu.be/WjTZwO7vcF

Reflections on Pandemic (H1N1) 2009 and the International Response

Gabriel Leung and Angus Nicoll provide their reflections on the international response to the 2009 H1N1 influenza pandemic, including what went well and what changes need to be made in anticipation of future flu pandemics

Second-order necessary conditions in optimal control: Accessory-problem results without normality conditions

An optimal control problem, which includes restrictions on the controls and equality/inequality constraints on the terminal states, is formulated. Second-order necessary conditions of the accessory-problem type are obtained in the absence of normality conditions. It is shown that the necessary conditions generalize and simplify prior results due to Hestenes (Ref. 5) and Warga (Refs. 6 and 7).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45219/1/10957_2004_Article_BF00934437.pd

The Presidency and the Executive Branch in Latin America: What We Know and What We Need to Know

The presidential politics literature depicts presidents either as all- powerful actors or figureheads and seeks to explain outcomes accordingly. Th e president and the executive branch are nonetheless usually treated as black boxes, particularly i n developing countries, even though the presidency has evolved into an extremely complex branch of government. While these developments have been studied in the U nited States, far less i s known in other countries, particularly in Latin America, where presi dential systems have been considered the source of all goods and evils. To help close the knowledge gap and explore differences in policymaking characteristics not only between Latin America and the US but also across Latin American countries, this paper s ummarizes the vast literature on the organization and resources of the Executive Branch in the Americas and sets a research agenda for the study of Latin American presidencies.Fil: Bonvecchi, Alejandro. Universidad Torcuato Di Tella. Departamento de Ciencia Política y Estudios Internacionales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Scartascini, Juan Carlos. Banco Interamericano de Desarrollo; Estados Unido

Adenosine A2A receptors in Parkinson’s disease treatment

Latest results on the action of adenosine A2A receptor antagonists indicate their potential therapeutic usefulness in the treatment of Parkinson’s disease. Basal ganglia possess high levels of adenosine A2A receptors, mainly on the external surfaces of neurons located at the indirect tracts between the striatum, globus pallidus, and substantia nigra. Experiments with animal models of Parkinson’s disease indicate that adenosine A2A receptors are strongly involved in the regulation of the central nervous system. Co-localization of adenosine A2A and dopaminergic D2 receptors in striatum creates a milieu for antagonistic interaction between adenosine and dopamine. The experimental data prove that the best improvement of mobility in patients with Parkinson’s disease could be achieved with simultaneous activation of dopaminergic D2 receptors and inhibition of adenosine A2A receptors. In animal models of Parkinson’s disease, the use of selective antagonists of adenosine A2A receptors, such as istradefylline, led to the reversibility of movement dysfunction. These compounds might improve mobility during both monotherapy and co-administration with L-DOPA and dopamine receptor agonists. The use of adenosine A2A receptor antagonists in combination therapy enables the reduction of the L-DOPA doses, as well as a reduction of side effects. In combination therapy, the adenosine A2A receptor antagonists might be used in both moderate and advanced stages of Parkinson’s disease. The long-lasting administration of adenosine A2A receptor antagonists does not decrease the patient response and does not cause side effects typical of L-DOPA therapy. It was demonstrated in various animal models that inhibition of adenosine A2A receptors not only decreases the movement disturbance, but also reveals a neuroprotective activity, which might impede or stop the progression of the disease. Recently, clinical trials were completed on the use of istradefylline (KW-6002), an inhibitor of adenosine A2A receptors, as an anti-Parkinson drug