54 research outputs found
Von Bezold assimilation effect reverses in stereoscopic conditions
Lightness contrast and lightness assimilation are opposite phenomena: in contrast,
grey targets appear darker when bordering bright surfaces (inducers) rather than dark ones; in
assimilation, the opposite occurs. The question is: which visual process favours the occurrence
of one phenomenon over the other? Researchers provided three answers to this question. The
first asserts that both phenomena are caused by peripheral processes; the second attributes their
occurrence to central processes; and the third claims that contrast involves central processes,
whilst assimilation involves peripheral ones. To test these hypotheses, an experiment on an IT
system equipped with goggles for stereo vision was run. Observers were asked to evaluate the
lightness of a grey target, and two variables were systematically manipulated: (i) the apparent
distance of the inducers; and (ii) brightness of the inducers. The retinal stimulation was kept
constant throughout, so that the peripheral processes remained the same. The results show that
the lightness of the target depends on both variables. As the retinal stimulation was kept constant, we
conclude that central mechanisms are involved in both lightness contrast and lightness assimilation
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The acute effects of cocoa flavanols on temporal and spatial attention
In this study, we investigated how the acute physiological effects of cocoa flavanols might result in specific cognitive changes, in particular in temporal and spatial attention. To this end, we pre-registered and implemented a randomized, double-blind, placebo- and baseline-controlled crossover design. A sample of 48 university students participated in the study and each of them completed the experimental tasks in four conditions (baseline, placebo, low dose, and high-dose flavanol), administered in separate sessions with a 1-week washout interval. A rapid serial visual presentation task was used to test flavanol effects on temporal attention and integration, and a visual search task was similarly employed to investigate spatial attention. Results indicated that cocoa flavanols improved visual search efficiency, reflected by reduced reaction time. However, cocoa flavanols did not facilitate temporal attention nor integration, suggesting Potential underlying mechanisms are discussed
Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia
Obstetric complications play a role in the pathophysiology of schizophrenia. However, the biological consequences during neurodevelopment until adulthood are unknown. Microarrays have been used for expression profiling in four brain regions of a rat model of neonatal hypoxia as a common factor of obstetric complications. Animals were repeatedly exposed to chronic hypoxia from postnatal (PD) day 4 through day 8 and killed at the age of 150 days. Additional groups of rats were treated with clozapine from PD 120–150. Self-spotted chips containing 340 cDNAs related to the glutamate system (“glutamate chips”) were used. The data show differential (up and down) regulations of numerous genes in frontal (FR), temporal (TE) and parietal cortex (PAR), and in caudate putamen (CPU), but evidently many more genes are upregulated in frontal and temporal cortex, whereas in parietal cortex the majority of genes are downregulated. Because of their primary presynaptic occurrence, five differentially expressed genes (CPX1, NPY, NRXN1, SNAP-25, and STX1A) have been selected for comparisons with clozapine-treated animals by qRT-PCR. Complexin 1 is upregulated in FR and TE cortex but unchanged in PAR by hypoxic treatment. Clozapine downregulates it in FR but upregulates it in PAR cortex. Similarly, syntaxin 1A was upregulated in FR, but downregulated in TE and unchanged in PAR cortex, whereas clozapine downregulated it in FR but upregulated it in PAR cortex. Hence, hypoxia alters gene expression regionally specific, which is in agreement with reports on differentially expressed presynaptic genes in schizophrenia. Chronic clozapine treatment may contribute to normalize synaptic connectivity
Noninertial effects on a Dirac neutral particle inducing an analogue of the Landau quantization in the cosmic string spacetime
We discuss the behaviour of external fields that interact with a Dirac
neutral particle with a permanent electric dipole moment in order to achieve
relativistic bound states solutions in a noninertial frame and in the presence
of a topological defect spacetime. We show that the noninertial effects of the
Fermi-Walker reference frame induce a radial magnetic field even in the absence
of magnetic charges, which is influenced by the topology of the cosmic string
spacetime. We then discuss the conditions that the induced fields must satisfy
to yield the relativistic bound states corresponding to the
Landau-He-McKellar-Wilkens quantization in the cosmic string spacetime. Finally
we obtain the Dirac spinors for positive-energy solutions and the Gordon
decomposition of the Dirac probability current.Comment: 15 pages, no figure, this paper will be published in volume 42 of the
Brazilian Journal of Physic
Consensus Paper: Cerebellum and Social Cognition.
The traditional view on the cerebellum is that it controls motor behavior. Although recent work has revealed that the cerebellum supports also nonmotor functions such as cognition and affect, only during the last 5 years it has become evident that the cerebellum also plays an important social role. This role is evident in social cognition based on interpreting goal-directed actions through the movements of individuals (social "mirroring") which is very close to its original role in motor learning, as well as in social understanding of other individuals' mental state, such as their intentions, beliefs, past behaviors, future aspirations, and personality traits (social "mentalizing"). Most of this mentalizing role is supported by the posterior cerebellum (e.g., Crus I and II). The most dominant hypothesis is that the cerebellum assists in learning and understanding social action sequences, and so facilitates social cognition by supporting optimal predictions about imminent or future social interaction and cooperation. This consensus paper brings together experts from different fields to discuss recent efforts in understanding the role of the cerebellum in social cognition, and the understanding of social behaviors and mental states by others, its effect on clinical impairments such as cerebellar ataxia and autism spectrum disorder, and how the cerebellum can become a potential target for noninvasive brain stimulation as a therapeutic intervention. We report on the most recent empirical findings and techniques for understanding and manipulating cerebellar circuits in humans. Cerebellar circuitry appears now as a key structure to elucidate social interactions
Entanglement entropy of black holes
The entanglement entropy is a fundamental quantity which characterizes the
correlations between sub-systems in a larger quantum-mechanical system. For two
sub-systems separated by a surface the entanglement entropy is proportional to
the area of the surface and depends on the UV cutoff which regulates the
short-distance correlations. The geometrical nature of the entanglement entropy
calculation is particularly intriguing when applied to black holes when the
entangling surface is the black hole horizon. I review a variety of aspects of
this calculation: the useful mathematical tools such as the geometry of spaces
with conical singularities and the heat kernel method, the UV divergences in
the entropy and their renormalization, the logarithmic terms in the
entanglement entropy in 4 and 6 dimensions and their relation to the conformal
anomalies. The focus in the review is on the systematic use of the conical
singularity method. The relations to other known approaches such as 't Hooft's
brick wall model and the Euclidean path integral in the optical metric are
discussed in detail. The puzzling behavior of the entanglement entropy due to
fields which non-minimally couple to gravity is emphasized. The holographic
description of the entanglement entropy of the black hole horizon is
illustrated on the two- and four-dimensional examples. Finally, I examine the
possibility to interpret the Bekenstein-Hawking entropy entirely as the
entanglement entropy.Comment: 89 pages; an invited review to be published in Living Reviews in
Relativit
Beyond equilibrium climate sensitivity
ISSN:1752-0908ISSN:1752-089
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Non-standard errors
In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence generating process (EGP). We claim that EGP variation across researchers adds uncertainty: Non-standard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for better reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants
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