25 research outputs found

    Automação Domótica Simulada Utilizando Algoritmo Genético Especializado na Redução do Consumo de Energia

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    Este trabalho apresenta o desenvolvimento de um sistema para redução do consumo de energia elétrica residencial utilizando a técnica de algoritmos genéticos. A metodologia consistiu na criação de cenários de teste, obtenção de dados relevantes, para atingir os objetivos de otimização, e a utilização de um modelo matemático para o cálculo do consumo de energia. As simulações termo energéticas realizadas sob os cenários-teste, sugeriram aos usuários do sistema melhorias para a redução do consumo de energia domótica, demonstrando a viabilidade prática da solução proposta

    Assessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle

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    Introduction During the menstrual cycle, the mammary gland goes through sequential waves of proliferation and apoptosis. in mammary epithelial cells, hormonal and non-hormonal factors regulate apoptosis. To determine the cyclical effects of gonadal steroids on breast homeostasis, we evaluated the apoptotic index ( AI) determined by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling ( TUNEL) staining in human mammary epithelial cells during the spontaneous menstrual cycle and correlated it with cellular proliferation as determined by the expression of Ki-67 during the same period.Methods Normal breast tissue samples were obtained from 42 randomly selected patients in the proliferative ( n = 21) and luteal ( n = 21) phases. Menstrual cycle phase characterization was based on the date of the last and subsequent menses, and on progesterone serum levels obtained at the time of biopsy.Results the proliferation index ( PI), defined as the number of Ki-67-positive nuclei per 1,000 epithelial cells, was significantly larger in the luteal phase (30.46) than in the follicular phase (13.45; P = 0.0033). the AI was defined as the number of TUNEL-positive cells per 1,000 epithelial cells. the average AI values in both phases of the menstrual cycle were not statistically significant ( P = 0.21). However, the cell renewal index ( CRI = PI/AI) was significantly higher in the luteal phase ( P = 0.033). A significant cyclical variation of PI, AI and CRI was observed. PI and AI peaks occurred on about the 24th day of the menstrual cycle, whereas the CRI reached higher values on the 28th day.Conclusions We conclude that proliferative activity is dependent mainly on hormonal fluctuations, whereas apoptotic activity is probably regulated by hormonal and non-hormonal factors.Universidade Federal de São Paulo, Dept Gyneol, Mastol Div, São Paulo, BrazilStanford Univ, Sch Med, Dept Neurosurg, Stanford, CA 94305 USAAPC Pathol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Gyneol, Mastol Div, São Paulo, BrazilWeb of Scienc

    Characterization of buriti (Mauritia flexuosa) pulp oil and the effect of its supplementation in an In vivo experimental model.

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    Mauritia flexuosa (buriti) pulp oil contains bioactive substances and lipids that are protective against cardiovascular and inflammatory diseases. We performed physical and chemical analyses to verify its quality and stability. buriti oil was stable according to the Rancimat test, presenting an induction period of 6.6 h. We evaluated the effect of supplementation with crude buriti oil and olive oil on metabolic parameters in 108 Swiss mice for 90 days. We investigated six groups: extra virgin olive oil (EVOO) 1 and 2 (1000 and 2000 mg/kg), buriti oil (BO) 1 and 2 (1000 and 2000 mg/kg), synergic (S) (BO1 + EVOO1), and control (water dose 1000 mg/kg). The animals were euthanized to examine their blood, livers, and fats. The supplementation did not interfere with food consumption, weight gain, and histological alterations in the liver. Group S showed the strongest relationship with the fractions HDL-c and non-HDL-c, indicating a possible cardioprotective effect. Moreover, we observed significantly higher IL-6 levels in the control, EVOO2, and BO1 groups than in the EVOO1 group. Resistin was also significantly higher for the synergic treatment than for the control. We conclude that BO combined with EVOO could be an excellent food supplement for human consumption

    Modelização de agroecossistemas, instrumento revelador das relações sócio-econômico-ecológicas de experiências.

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    A agricultura consiste no processo de conversão de insumos e recursos ecológicos em pro-dutos que se processam na unidade ecológica denominada de agroecossitemas. Diferentes lógicas de gestão podem ser empregadas entre os agroecossistemas de modo que essas dinâmicas podem variar de processos mais complexos, ou simplificados. Nesse sentido, ado-tou-se um recorte da Metodologia de Avaliação Econômica-Ecológica de Agroecossitemas da AS-PTA para realizar um diagnóstico e levantar informações visando estruturar a rede de fluxos de agroecossistemas (A1 e A2) e compará-los entre si. As experiências mantém relações contrastantes devido as diferentes orientações e estratégias técnicas e de gestão empregadas pelo Núcleo Social Gestor dos Agroecossistemas (NSGA). A análise refletida é fundamental para que seus atores sociais possam orientar ou reorientar a gestão de seus agroecossistemas a partir de processos adaptativos.Anais do VI Congresso Latino-americano de Agroecologia; X Congresso Brasileiro de Agroecologia; V Seminário de Agroecologia do Distrito Federal e Entorno; 12 a 15 de setembro de 2017, Brasília/D
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