Protein-losing enteropathy associated with Henoch-Schönlein purpura

The gastrointestinal manifestations of Henoch-Schönlein purpura include abdominal pain, gastrointestinal bleeding, intussusception, and perforation. Protein-losing enteropathy is rarely associated with Henoch-Schönlein purpura. Two pediatric patients with Henoch-Schönlein purpura who developed protein-losing enteropathy are reported. Tc-99m human serum albumin scintigraphy is useful in the detection of protein-losing enteropathy

The Culture of Prison Management: Measurement of Risk Control Culture in the English and Japanese Prison Services using the Grid and Group Cultural Theory

Comparative analysis is crucial to academic studies of public administration because it provides understanding of the nature of different types of public service institution: in particular, it helps to show what they do and don’t have in common, what kinds of institution they are, and what kinds of problems they face. However, in order to effectively conduct comparative research of public service institutions it is important that some thought is given to how they can best be compared. Accordingly, it is argued in this study that the differences between public service institutions can be appropriately analysed by examining their respective risk control cultures. This study makes use of the grid and group cultural theory, as developed by Mary Douglas, Aaron Wildavsky and Christopher Hood, to analyse the risk control cultures of the English and Japanese prison services in regard to two specific types of risk, namely suicide and violence. The results show that particular patterns of organizational behaviour within the English and Japanese prison services can be identified with their respective risk control cultures. More specifically, the English prison service tends to try to control risk by using formal rules and granting strong leadership roles to governors. By contrast, the Japanese prison service tends to use informal rules and group pressures to control risk. Furthermore, the peculiar organizational patterns of risk control within both organizations are often not recognised by their members. As a result, the strengths and weaknesses of organizations can be identified by analysing the patterns of risk control behaviour within them

Clinical Teaching Behavior Factors

Aims：Challenges of novice nursing educators are initiated when they begin to engage in clinical teaching, often due to lack of support from experienced colleagues. This study was aimed to identify the factors associated with clinical teaching behaviors of novice nurse educators of Diploma Nursing schools in western Japan. Method：Of ２３１ Diploma Nursing schools in Western Japan,９２ institutions（３９．８３％）agreed to participate. The study participants were １４４ novice nursing educators with less than five years of teaching experience. Anonymized self-administered questionnaires including the Scale of Other Educators’ Support（SOES）and organizational education, associated with the Scale of Clinical Teaching Behaviors（SCTB）were mailed to participants. The SOES factors of work and reflection supports, organizational education factors of information-sharing opportunity and mini-workshops were used to determine association with SCTB. The multiple regression analysis with stepwise method was used for SCTB. Results：Conducting to multivariate analysis, age（p =０．０１）, information-sharing among nursing educators（p =０．０４）, participation in mini-workshops on clinical practice（p =０．０４）, and work support（p =０．０３）were significantly associated with the improvement of SCTB. Then, reflection support was significantly associated with the deterioration of SCTB（p =０．０２）. Discussion：The work support meaning direct advice and guidance from other nursing educators can enhance the effectiveness for SCTB. The reflection support encouraged the novice nurses to reflect on their teaching behaviors, but only made them aware of problems to be solved, which lowered the SCTB. The information-sharing opportunity and mini-workshops might be effective opportunities to learn about teaching behaviors to increase the SCTB. Conclusion：The SOES and organizational education factors enhance teaching behaviors measured by SCTB among novice nursing educators. Therefore, in developing novice nursing educators, it is necessary to create opportunities indicating these factors for novice nursing educators to learn about practical training and to collaborate with other nursing educators

Genome-wide screening of the genes required for tolerance to vanillin, which is a potential inhibitor of bioethanol fermentation, in Saccharomyces cerevisiae

<p>Abstract</p> <p>Background</p> <p>Lignocellulosic materials are abundant and among the most important potential sources for bioethanol production. Although the pretreatment of lignocellulose is necessary for efficient saccharification and fermentation, numerous by-products, including furan derivatives, weak acids, and phenolic compounds, are generated in the pretreatment step. Many of these components inhibit the growth and fermentation of yeast. In particular, vanillin is one of the most effective inhibitors in lignocellulose hydrolysates because it inhibits fermentation at very low concentrations. To identify the genes required for tolerance to vanillin, we screened a set of diploid yeast deletion mutants, which are powerful tools for clarifying the function of particular genes.</p> <p>Results</p> <p>Seventy-six deletion mutants were identified as vanillin-sensitive mutants. The numerous deleted genes in the vanillin-sensitive mutants were classified under the functional categories for 'chromatin remodeling' and 'vesicle transport', suggesting that these functions are important for vanillin tolerance. The cross-sensitivity of the vanillin-sensitive mutants to furan derivatives, weak acids, and phenolic compounds was also examined. Genes for ergosterol biosynthesis were required for tolerance to all inhibitory compounds tested, suggesting that ergosterol is a key component of tolerance to various inhibitors.</p> <p>Conclusion</p> <p>Our analysis predicts that vanillin tolerance in <it>Saccharomyces cerevisiae </it>is affected by various complicated processes that take place on both the molecular and the cellular level. In addition, the ergosterol biosynthetic process is important for achieving a tolerance to various inhibitors. Our findings provide a biotechnological basis for the molecular engineering as well as for screening of more robust yeast strains that may potentially be useful in bioethanol fermentation.</p

Analysis of Developmental Changes in Avian DNA Methylation Using a Novel Method for Quantifying Genome-wide DNA Methylation

Individual differentiated somatic cells and undifferentiated stem cells have common genome, although their functions or morphological characters are very different. These differences are derived from difference of gene expression pattern. DNA methylation is generally key factor of Suppression of gene and its level is globally change during mammalian early development. But, in birds, whether genome-wide changes in DNA methylation occur during embryonic development is still unknown. Here, we show that genome-wide DNA methylation to assess occurrence during early chick embryonic development. We found that the methylation status at stage 1 was approximately 57%, after which it gradually decreases, reaching a minimum at stage 10 (33%). After stage 10, DNA methylation gradually increased. These results should contribute to clarify the epigenetic mechanisms in birds.ArticleJOURNAL OF POULTRY SCIENCE. 46(4): 286-290(2009)journal articl