Comparative anatomical and morphological characteristics of two subspecies of Melissa officinalis L. (Lamiaceae)

Received: February 23rd, 2022 ; Accepted: May 22nd, 2022 ; Published: July 30th, 2022 ; Correspondence: [email protected] aim of the research is to comprehensively compare the anatomical and morphological structures of plants of Melissa officinalis subsp. officinalis (‘Krymchanka’ and ‘Lada’ varieties) and of M. officinalis subsp. аltissima (Sm.) Arcang. These plants have pronounced differences in morphological features and production indexes. They are grown in the collection of aromatic plants of the Research Institute of Agriculture of the Crimea (Krymskaya Roza village, Belogorsky district of Crimea). These studies will allow us to supplement the botanical characteristics of both subspecies of M. officinalis, and also to evaluate their plasticity and possibilities of adaptation to growing conditions. For examination we collected plants in the flowering phase. Anatomical study was carried out using a fixed (alcohol: glycerin : water in a ratio of 1: 1: 1) and native preparation. A complex of mesomorphic and xeromorphic characters is established, that confirms the high plasticity and determines the adaptive capabilities of the species when introduced into various soil and climatic conditions. A variety of epidermal structures was revealed, which are represented by single and multicellular non-glandular trichomes and various types of glandular structures. Among them, trichomes with a multicellular pedicle and a unicellular head, which we found only in M. officinalis subsp. officinalis

ПАТОФИЗИОЛОГИЧЕСКИЕ АСПЕКТЫ ПРОЦЕССА ЗАЖИВЛЕНИЯ РАН В НОРМЕ И ПРИ СИНДРОМЕ ДИАБЕТИЧЕСКОЙ СТОПЫ

The main cause of long-term healing of ulcers in patients with diabetic foot is considered to be direct mechanical damage when walking due to reduced sensitivity to due to neuropathy, hyperglycemia, infection and peripheral artery disease. These factors determine the standard approaches to the treatment of diabetic foot, which include: offloading, glycemic control, debridement of ulcers, antibiotic therapy and revascularization. Recently, however, disturbances in the healing process of the skin in diabetes recognized an additional factor affecting the timing of healing patients with diabetic foot. Improved understanding and correction of cellular, molecular and biochemical abnormalities in chronic wound in combination with standard of care for diabetic foot gives new hope to solve the problem of ulcer healing in diabetes. Традиционно причинами длительного заживления язв при синдроме диабетической стопы (СДС) считаются прямое механическое повреждение при ходьбе в связи со снижением болевой чувствительности на фоне нейропатии, гипергликемия, инфицирование и нарушение кровоснабжения. Данные факторы определяют стандартные подходы к лечению СДС, включающие в себя: разгрузку пораженной конечности, гликемический контроль, хирургическую обработку язв, антибактериальную терапию и реваскуляризацию. Однако в последнее время нарушения непосредственно в процессе заживления кожных покровов при сахарном диабете (СД) признаются отдельным фактором определяющим вероятность и сроки излечения пациента с СДС. Улучшение понимания и коррекция клеточных, молекулярных и биохимических нарушений в хронической ране в сочетании с соблюдением стандартов лечения СДС дает новую надежду в решении проблемы заживления язв при СД.

Preparation of iron molybdate catalysts for methanol to formaldehyde oxidation based on ammonium molybdoferrate(II) precursor

It was demonstrated that iron molybdate catalysts for methanol oxidation can be prepared using Fe(II) as a precursor instead of Fe(III). This would allow for reduction of acidity of preparation solutions as well as elimination of Fe(III) oxide impurities which are detrimental for the process selectivity. The system containing Fe(II) and Mo(VI) species in aqueous solution was investigated using UV–Vis spectroscopy. It was demonstrated that three types of chemical reactions occur in the Fe(II)–Mo(VI) system: (i) formation of complexes between Fe(II) and molybdate(VI) ions, (ii) inner sphere oxidation of coordinated Fe(II) by Mo(VI) and (iii) decomposition of the Fe–Mo complexes to form scarcely soluble Fe(III) molybdate, Mo(VI) hydrous trioxide and molybdenum blue. Solid molybdoferrate(II) prepared by interaction of Fe(II) and Mo(VI) in solution was characterized by EDXA, TGA, DTA and XRD and a scheme of its thermal evolution proposed. The iron molybdate catalyst prepared from Fe(II) precursor was tested in methanol-toformaldehyde oxidation in a continuous flow fixed-bed reactor to show similar activity and selectivity to the conventional catalyst prepared with the use of Fe(III)

Peroxide-based route for the synthesis of zinc titanate powder

In this work the thermodynamical solubility diagrams of zinc and titanium hydroxides were reviewed in order to determine the conditions for maximum degree of phase composition homogenization of precipitates. Experimental investigation of dependency of titanium peroxohydroxide solubility on solution acidity has been carried out and coprecipitation of zinc ions has been studied. It was concluded that precipitation by constant addition of mixed salts and base solutions into the mother liquor with constant acidity of pH 8.5 allows maximizing homogenization of precipitate composition. Thermal treatment process of mixed zinc and titanium hydroxides coprecipitated with hydrogen peroxide was studied using thermogravimetric analysis, differential thermal analysis and X-ray diffraction methods. It was found that precipitates of co-precipitated mixtures of zinc and titanium hydroxides contained impurities of salts precursors of the Zn (NO3)2 and TiOCl2 at a level of 1%. The experimental data demonstrate the influence of hydrogen peroxide on crystal growth rate of the zinc titanate during thermal treatment. The temperature ranges and kinetic parameters of hydroxide mixture dehydration, decomposition of the titanium peroxohydroxide and precursor impurities were determined

Surface Properties of Synthetic Calcium Hydroxyapatite

The composition of the adsorption centres of hydrated calcium hydroxyapatite was studied. It was found that the adsorption of organic bases was due to the formation of surface hydrogen bonds between their nitrogen atoms and the ≡POH groups of hydroxyapatite. Aromatic acids and alcohols were adsorbed in an ionic form due to the formation of intraspheric complexes with surface Ca 2+ cations. It was concluded that the adsorbability of organic compounds depends on the relationship between the greatest effective charges on their atoms and the atoms of water molecules

Antioxidant therapy in the treatment of dental diseases in children with neuropsychiatric disorders

The objective. Assessment of the dynamics of oxidative stress markers in the oral cavity in children with neuropsychiatric pathology after oral antioxidant therapy with vitamins С and Е. Patients and methods. The study included 72 patients with neuropsychiatric diseases (aged 7–17 years) and 56 somatically healthy children of the same age. In all children with neuropsychiatric diseases (mental retardation, Down’s syndrome, autism with mental retardation, infantile cerebral palsy with mental retardation, and schizophrenia) the signs of oxidative stress of varied degree were found in the oral cavity. The dynamics of the parameters of oxidative stress in the oral cavity was studied against the background of daily treatment with antioxidants (vitamins Е and С) for 4 months. Результаты. Before treatment, in the oral fluid of children with neuropsychiatric disorders a growth of the key markers of oxidative stress was found: catalase 40.6 ± 5.4 μmol min–1 g(protein)–1 (in controls 28.75 ± 4.5 μmol min–1 g(protein)–1), superoxide dismutase 29.9 ± 3.7 act. g(protein)–1 (in controls 16.55 ± 2.4 act. g(protein)–1), maximum chemiluminescence flash 0.146 ± 0.029 c.u. (in controls 0.035 ± 0.016 c.u.), chemiluminescent area 0.284 ± 0.023 c.u. (0.135 ± 0.013 c.u. in controls) and a decrease of the integral parameter of the functioning of anti-radical defence enzymes to 27.7 ± 12.1 cond. units. CAT/SOD compared with the similar parameter in the control group 101.9 ± 19.9 cond.units CAT/SOD (p < 0.05). After antioxidant therapy, the activity of antioxidant defence enzymes and the parameters of the state of low-molecular antioxidants significantly, maximally approaching the control values (p < 0.05). The value of the integral parameter of the functioning of anti-radical defence enzymes in children with psychoneurological diseases increased after antioxidant therapy by 73.6% (p < 0.05). Conclusion. We have established a restoration of the activity of low-molecular antioxidants and enzymes of antioxidant defence of oral fluids in children with neuropsychiatric disorders after antioxidant treatment. © 2019, Dynasty Publishing House. All rights reserved