Study of the radiative decay ϕ→ηγ\phi \to \eta \gamma with CMD-2 detector

Using the $1.9 pb^{-1}$ of data collected with the CMD-2 detector at VEPP-2M the decay mode $\phi \to \eta \gamma$, $\eta \to \pi^+\pi^-\pi^0$ has been studied. The obtained branching ratio is B($\phi \to \eta \gamma) = (1.18 \pm 0.03 \pm 0.06)$.Comment: 13 pages, 5 figures, LaTex2e, to be published in Phys. Lett.

Observation of KS0K_S^0 semileptonic decays with CMD-2 detector

The decay $K_S^0 \to \pi e \nu$ has been observed by the CMD-2 detector at the e^+e^- collider VEPP-2M at Novosibirsk. Of 6 million produced $K_L^0K_S^0$ pairs, $75 \pm 13$ events of the $K_S^0 \to \pi e \nu$ decay were selected. The corresponding branching ratio is $B(K_S^0 \to \pi e \nu)=(7.2 \pm 1.4)\times10^{-4}$. This result is consistent with the evaluation of $B(K_S^0 \to \pi e \nu)$ from the $K_L^0$ semileptonic rate and $K_S^0$ lifetime assuming $\Delta S=\Delta Q$ .Comment: 7 pages, 6 figures, LaTex2e. Submitted to Phys.Lett.

Measurement of omega meson parameters in pi^+pi^-pi^0 decay mode with CMD-2

About 11 200 e^+e^- -> omega -> pi^+pi^-pi^0 events selected in the center of mass energy range from 760 to 810 MeV were used for the measurement of the \omega meson parameters. The following results have been obtained: sigma _{0}=(1457 \pm 23 \pm 19)nb, m_{\omega}=(782.71 \pm 0.07 \pm 0.04) MeV/c^{2}, \Gamma_{\omega}=(8.68 \pm 0.23 \pm 0.10) MeV, \Gamma_{e^+e^-}\cdot Br (\omega -> pi^+pi^-pi^0)= (0.528 \pm 0.012 \pm 0.007) \cdot 10^{-3} MeV.Comment: 8 pages, 4 figure

Study of the process e+e- to pi+pi-pi+pi-pi0 with CMD-2 detector

The process e+e- to pi+ pi- pi+ pi- pi0 has been studied in the center of mass energy range 1280 -- 1380 MeV using 3.0 1/pb of data collected with the CMD-2 detector in Novosibirsk. Analysis shows that the cross section of the five pion production is dominated by the contributions of the eta pi+pi- and omega pi+pi- intermediate states.Comment: 8 pages, 3 figure. Submitted to Phys. Lett.

Study of the Process e+e−→KL0KS0e^+e^- \to K^0_L K^0_S in the C.M.Energy Range 1.05-1.38 GeV with CMD-2

The process $e^+e^- \to K^0_L K^0_S$ has been studied with the CMD-2 detector using about 950 events detected in the center-of-mass energy range from 1.05 to 1.38 GeV. The cross section exceeds the expectation based on the contributions of the rho(770), omega(782) and phi(1020) mesons only.Comment: 12 pages, 3 figures, uses elsart.cls, submitted to Physics Letters

High-statistics measurement of the pion form factor in the rho-meson energy range with the CMD-2 detector

We present a measurement of the pion form factor based on e+e- annihilation data from the CMD-2 detector in the energy range 0.6<sqrt(s)<1.0 GeV with a systematic uncertainty of 0.8%. A data sample is five times larger than that used in our previous measurement.Comment: 18 pages, 10 figures. Added comparison with KLOE measurement, minor updates. Accepted by PL

Observation of the conversion decay ϕ→π0e+e−\phi\to\pi^0e^+e^- at CMD-2

Using 15.1^{-1} of data collected by CMD-2 in the $\phi$-meson energy range, the branching ratio of the conversion decay $\phi\to\pi^0e^+e^-$ has been measured for the first time: B(\phi\to\pi^0e^+e^-) = (1.22 \pm 0.34 \pm 0.21) \cdot 10 ^{-5}.Comment: 13 pages, 6 PostScript figures, uses refmerge.sty. To be published in Phys. Lett.

Cross section of the reaction e+e−→π+π−π+π−e^+ e^- \to \pi^+\pi^-\pi^+\pi^- below 1 GeV at CMD-2

Using 3.07 ${pb}^{-1}$ of data collected in the energy range 0.60-0.97 GeV by CMD-2, about 150 events of the process \epm \to \pch have been selected. The energy dependence of the cross section agrees with the assumption of the $a_1(1260) \pi$ intermediate state which is dominant above 1 GeV. For the first time \fourpi events are observed at the $\rho$ meson energy. Under the assumption that all these events come from the $\rho$ meson decay, the value of the cross section at the $\rho$ meson peak corresponds to the following decay width: \Gamma(\rho^0 \to \fourpi) = (2.8 \pm 1.4 \pm 0.5) {keV} or to the branching ratio B(\rho^0 \to \fourpi) = (1.8 \pm 0.9 \pm 0.3) \cdot 10 ^{-5}.Comment: 15 pages, 5 figure

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread highlight the importance of understanding the full molecular details of coronavirus infection and pathogenesis. Here, we compared a variety of replication features of SARS-CoV-2 and SARS-CoV and analysed the cytopathology caused by the two closely related viruses in the commonly used Vero E6 cell line. Compared to SARS-CoV, SARS-CoV-2 generated higher levels of intracellular viral RNA, but strikingly about 50-fold less infectious viral progeny was recovered from the culture medium. lmmunofluorescence microscopy of SARS-CoV-2-infected cells established extensive cross-reactivity of antisera previously raised against a variety of non-structural proteins, membrane and nucleocapsid protein of SARS-CoV. Electron microscopy revealed that the ultrastructural changes induced by the two SARS viruses are very similar and occur within comparable time frames after infection. Furthermore, we determined that the sensitivity of the two viruses to three established inhibitors of coronavirus replication (remdesivir, alisporivir and chloroquine) is very similar, but that SARS-CoV-2 infection was substantially more sensitive to pre-treatment of cells with pegylated interferon alpha. An important difference between the two viruses is the fact that - upon passaging in Vero E6 cells - SARS-CoV-2 apparently is under strong selection pressure to acquire adaptive mutations in its spike protein gene. These mutations change or delete a putative furin-like cleavage site in the region connecting the S1 and S2 domains and result in a very prominent phenotypic change in plaque assays.Microscopic imaging and technolog

Study of the Process e+ e- --> omega pi0 --> pi0 pi0 gamma in c.m. Energy Range 920--1380 MeV at CMD-2

The cross section of the process e+ e- --> omega pi0 --> pi0 pi0 gamma has been measured in the c.m. energy range 920-1380 MeV with the CMD-2 detector. Its energy dependence is well described by the interference of the rho(770) and rho'(1450) mesons decaying to omega pi0. Upper limits for the cross sections of the direct processes e+ e- --> pi0 pi0 gamma, eta pi0 gamma have been set.Comment: Accepted for publication in PL