Esophagogastric Ulcer in Pigs on Commercial Farms

Intensive swine production in modern conditions of breeding and use of technological processes has influenced the occurrence of wide range of breeding and technopathy diseases. One of the most abundant breeding diseases declared in literature as an independent disease is esophagogastric ulcer characterized by erosions and ulcers in mostly esophagogastric part and rarely in mucous part of stomach. Esophagogastric ulcer is a disease of multifactorial etiology caused by genetic predisposition, diet, and presence of certain pathogenic microorganisms (for example Helicobacter pylori). The goal of our research was to examine the frequency of esophagogastric ulcer in pigs on commercial farms. One commercial farm has its own slaughterhouse for producing meat of fattened pigs. In our experiment we used 103 pigs in fattening with body weight between 100 and 107 kg and aged from 6 to 7 months. In the process line of slaughterhouse we established thickening of esophageal surface, hyperkeratosis, nonstructural yellow surface in 37 of total of 103 animals, while erosion of esophageal part of stomach, surface damage which does not include damage of muscular layer of mucous membrane, was present in 29 of 103 animals. Ulcers of esophageal part of stomach which affect total thickness of mucosal membrane were present in 4 of 103 examined animals

VARIATIONS OF CLIMATE PARAMETERS AND THEIR IMPACT ON CABERNET SAUVIGNON AND SAUVIGNON BLANC PHENOLOGY IN CONDITIONS OF CENTRAL SERBIA

Research carried out in vineyard of King Peter I Karadjordjevic-Royal Winery at Oplenac-Topola municipality, on Sauvignon blanc and Cabernet sauvignon. Vineyard planted with Sauvignon blanc is geographically positioned at GPS coordinates N 44° 14' 4" and E 20° 41' 15" and Cabernet sauvignon is geographically positioned at GPS coordinates N 44° 14' 35" and E 20° 41' 22". Climat parameters (series from 1982-2011 year) included following parameters: mean monthly, vegetation (april-october) and annual temperature, active and effective temperature, precipitation distribution (annual and vegetation) and wind direction. Phenological observation included beginning and end of following phenophases: bleeding, budbreakt, shoot growing, flowering, berry development and ripening. The greatest variation Sauvignon blanc manifested in duration of grape ripening which is in 2010. lasted 46 days while in 2011. lasted 34 days. Cabernet sauvignon in 2011. had a lower number of days that have passed from bleeding to full maturity (209 days) compared to 2010., when it passed 217 days

The pragmatics of articles in Dutch children with specific language impairment

Previous studies have found that the morpho-syntactic aspects of grammatical morphemes, including articles, pose problems for Dutch-speaking children with Specific Language Impairment (SLI). In the present study it is demonstrated that article errors in Dutch children with SLI appear to be modulated by the pragmatic context to some extent. This study examines the pragmatic aspects of articles in 19 6- to 8-year-old children with SLI, comparing the results with those of 26 monolingual typically developing age-matched (TD-AM) and 17 language-matched (TD-LM) children. An elicitation task was used to test the specific discourse-new context (definite articles) and non-specific context (indefinite articles). In both contexts, the SLI group omitted articles more often than the TD-AM group, thus behaving similarly to the younger TD-LM group. The SLI group substituted articles more often than children in both control groups. Many children in the SLI group displayed variable behaviour and relatively many children with SLI used definite articles in non-specific contexts. We conclude that processing limitations in SLI may lead to less stable lexical knowledge of articles and hinder the successful integration of lexical, syntactic and pragmatic information that is required for target-like use of articles

Diagnosis and treatment of carotid body paraganglioma: 21 years of experience at a clinical center of Serbia

BACKGROUND: The carotid body paraganglioma (chemodectoma) is a relatively rare neoplasm of obscure origin. These are usually benign and commonly present as asymptomatic cervical mass. PATIENTS AND METHODS: Records of 12 patients (9 female and 3 male) with carotid body tumors treated between 1982 and 2003, treated at our center were retrospectively reviewed. Data on classification, clinical presentation, and surgical treatment were extracted from the case records. Surgical complications and treatment outcome were noted and survival was calculated by actuarial method. The literature on carotid body paraganglioma was reviewed. RESULTS: The average age of the patients was 52 years (range 30–78 years). Eight of these cases presented as a large asymptomatic non-tender neck mass, and two each presented with dysphagia, and hoarseness of voice. As per Shamblin classification seven of tumors were type II and 5 were types III. In 7 cases subadventitial tumor excision was performed, while in 5 associated resection of both external and internal carotid arteries was carried out. The artery was repaired by end-to-end anastomosis in one case, with Dacron graft in one case, and with saphenous vein graft in 3 cases. There was no operative mortality. After a mean follow-up of 6.2 years (range 6 months to 20 years), there were no signs of tumor recurrence in any of the cases. CONCLUSIONS: Surgical excision is the treatment of choice for carotid body paragangliomas although radiation therapy is an option for patients who are not ideal candidates for surgery. For the tumors that are in intimate contact with carotid arteries, the treatment by vascular surgeon is recommended

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception

Adult neural stem cells reside in a specialized niche in the subventricular zone (SVZ). Throughout life they give rise to adult-born neurons in the olfactory bulb (OB), thus contributing to neural plasticity and pattern discrimination. Here, we show that the neurovascular protein EGFL7 is secreted by endothelial cells and neural stem cells (NSCs) of the SVZ to shape the vascular stem-cell niche. Loss of EGFL7 causes an accumulation of activated NSCs, which display enhanced activity and re-entry into the cell cycle. EGFL7 pushes activated NSCs towards quiescence and neuronal progeny towards differentiation. This is achieved by promoting Dll4-induced Notch signalling at the blood vessel-stem cell interface. Fewer inhibitory neurons form in the OB of EGFL7-knockout mice, which increases the absolute signal conducted from the mitral cell layer of the OB but decreases neuronal network synchronicity. Consequently, EGFL7-knockout mice display severe physiological defects in olfactory behaviour and perception

CO2 dissolution and design aspects of a multiorifice oscillatory baffled column

Dissolution of CO2 in water was studied for a batch vertical multiorifice baffled column (MOBC) with varying orifice diameters (d0) of 6.4-30 mm and baffle open area (α) of 15-42%. Bubble size distributions (BSDs) and the overall volumetric CO2 mass transfer coefficient (KLa) were experimentally evaluated for very low superficial gas velocities, UG of 0.12-0.81 mm s-1, using 5% v/v CO2 in the inlet gas stream at a range of fluid oscillations (f = 0-10 Hz and x0 = 0-10 mm). Remarkably, baffles presenting large do = 30 mm and α = 36%, therefore in the range typically found for single-orifice oscillatory baffled columns, were outperformed with respect to BSD control and CO2 dissolution by the other baffle designs or the same aerated column operating without baffles or fluid oscillations. Flow visualization and bubble tracking experiments also presented in this study established that a small do of 10.5 mm combined with a small value of α = 15% generates sufficient, strong eddy mixing capable of generating and trapping an extremely large fraction of microbubbles in the MOBC. This resulted in increased interfacial area yielding KLa values up to 65 ± 12 h-1 in the range of the UG tested, representing up to 3-fold increase in the rate of CO2 dissolution when compared to the unbaffled, steady column. In addition, a modi fied oscillatory Reynolds number, Re′o and Strouhal number, St' were presented to assist on the design and scale-up of gas-liquid systems based on multiorifice oscillatory ba ffled columns. This work is relevant to gas-liquid or multiphase chemical and biological systems relying on efficient dissolution of gaseous compounds into a liquid medium.BBSRC -European Commissio

Typilus: Neural Type Hints

Type inference over partial contexts in dynamically typed languages is challenging. In this work, we present a graph neural network model that predicts types by probabilistically reasoning over a program's structure, names, and patterns. The network uses deep similarity learning to learn a TypeSpace -- a continuous relaxation of the discrete space of types -- and how to embed the type properties of a symbol (i.e. identifier) into it. Importantly, our model can employ one-shot learning to predict an open vocabulary of types, including rare and user-defined ones. We realise our approach in Typilus for Python that combines the TypeSpace with an optional type checker. We show that Typilus accurately predicts types. Typilus confidently predicts types for 70% of all annotatable symbols; when it predicts a type, that type optionally type checks 95% of the time. Typilus can also find incorrect type annotations; two important and popular open source libraries, fairseq and allennlp, accepted our pull requests that fixed the annotation errors Typilus discovered.Comment: Accepted to PLDI 202

Stabilization of mid-sized silicon nanoparticles by functionalization with acrylic acid

We present an enhanced method to form stable dispersions of medium-sized silicon nanoparticles for solar cell applications by thermally induced grafting of acrylic acid to the nanoparticle surface. In order to confirm their covalent attachment on the silicon nanoparticles and to assess the quality of the functionalization, X-ray photoelectron spectroscopy and diffuse reflectance infrared Fourier spectroscopy measurements were carried out. The stability of the dispersion was elucidated by dynamic light scattering and Zeta-potential measurements, showing no sign of degradation for months

High "Normal" blood glucose is associated with decreased brain volume and cognitive performance in the 60s: the PATH through Life Study

Context:Type 2 diabetes is associated with cerebral atrophy, cognitive impairment and dementia. We recently showed higher glucose levels in the normal range not to be free of adverse effects and to be associated with greater hippocampal and amygdalar atrophy in older community-dwelling individuals free of diabetes.Objective:This study aimed to determine whether blood glucose levels in the normal range