67 research outputs found

    Tree Stands and Their Productivity Dynamics at the Upper Growing Limit in Khibiny on the Background of Modern Climate Changes

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    Within the ecotone of the upper limit of woody vegetation on the southeastern macroslope of the Khibiny Mountain ridge (Kola Peninsula), the spatial and age structure, as well as features of the phytomass accumulation of spruce–birch stands, were studied. Analysis revealed that there was a manifold increase in the density and productivity of forest stands in the last century, and the upper border of the woodlands and dense forests has moved considerably higher into the mountains. All of this happened against the background of an increase in early summer temperatures and a longer growing season in the area in the 20th century. Our data will help simulate the response of mountain ecosystems in the region to future climate change. Β© 2019, Pleiades Publishing, Ltd

    Structure and Dynamics of Tree Stands at the Upper Timberline in the Western Part of the Putorana Plateau

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    Analysis of the age structure of Dahurian larch (Larix gmelinii Rupr.) forests in the western part of the Putorana Plateau (Sukhie Gory Range) and comparison of diachronous topographic maps and satellite images have revealed changes in the altitudinal position of the upper boundary of tree vegetation. the most significant changes occurred on south- and southwest-facing slopes. Correlations of trunk diameters with the phytomass of trees and its fractions have been found. the course of changes in the structure and phytomass of tree stands in the upper timberline over the past centuries has been reconstructed. Forest expansion has been facilitated by the general change in climate conditions (warming) in the study area.This study was supported by the Russian Science Foundation, project no. 17-14-01112

    Effect of propolis bioflavonoids on the antioxidant potential of ejaculate and on oxidative sperm DNA damage

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    The investigation was undertaken to assess the molecular mechanisms of antioxidant action of propolis bioflavonoids in pathospermia. It included the data of examining 75 infertile males and 36 fertile ones. The 3-month administration of the agent in a daily dose of 40 mg resulted in normalization of ejaculate parameters, a reduction in the levels of biomarkers for oxidative protein and sperm DNA damage, and recovery of the antioxidant status of seminal plasma.</em

    ΠžΡ†Π΅Π½ΠΊΠ° эффСктивности ΠΊΠ°Ρ‚ΠΈΠΎΠ½ΠΈΡ‚Π° КУ-2-8 ΠΏΡ€ΠΈ ΠΈΠ·Π²Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ ΠΈΠ· Π²ΠΎΠ΄Ρ‹ Π² присутствии ΠΈΠΎΠ½ΠΎΠ² ТСсткости

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    НавСдСно Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈ Π΄ΠΎΡΠ»Ρ–Π΄ΠΆΠ΅Π½ΡŒ Π· визначСння СфСктивності ΠΊΠ°Ρ‚Ρ–ΠΎΠ½Ρ–Ρ‚Ρƒ КУ-2-8 ΠΏΡ–Π΄ час вилучСння ΠΉΠΎΠ½Ρ–Π² ΠΌΡ–Π΄Ρ– Π· Π²ΠΎΠ΄ΠΈ Π² присутності ΠΉΠΎΠ½Ρ–Π² Торсткості Π·Π° Π½ΠΈΠ·ΡŒΠΊΠΈΡ… ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ†Ρ–ΠΉ ΠΉΠΎΠ½Ρ–Π² ΠΌΡ–Π΄Ρ–. Показано, Ρ‰ΠΎ Π² статичних ΡƒΠΌΠΎΠ²Π°Ρ… ΠΏΡ€ΠΈ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ†Ρ–Ρ— ΠΌΡ–Π΄Ρ– Π²Ρ–Π΄ 1 Π΄ΠΎ 30 ΠΌΠ³/Π΄ΠΌ3 вилучСння ΠΌΡ–Π΄Ρ– ΠΏΡ€ΠΎΡ…ΠΎΠ΄ΠΈΡ‚ΡŒ Π½Π΅Π΅Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎ як Π· Π΄ΠΈΡΡ‚ΠΈΠ»ΡŒΠΎΠ²Π°Π½ΠΎΡ—, Ρ‚Π°ΠΊ Ρ– Π· Π²ΠΎΠ΄ΠΎΠΏΡ€ΠΎΠ²Ρ–Π΄Π½ΠΎΡ— Π²ΠΎΠ΄ΠΈ Π½Π΅Π·Π°Π»Π΅ΠΆΠ½ΠΎ Π²Ρ–Π΄ Ρ„ΠΎΡ€ΠΌΠΈ ΠΉΠΎΠ½Ρ–Ρ‚Ρƒ. Π”Π°Π½ΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊ Π·Π½ΠΈΠΆΡƒΡ”Ρ‚ΡŒΡΡ ΠΏΡ–Π΄ час Π·Π±Ρ–Π»ΡŒΡˆΠ΅Π½Π½Ρ об’єму Ρ€ΠΎΠ·Ρ‡ΠΈΠ½Ρƒ ΠΏΡ€ΠΈ фіксованому об’ємі ΠΉΠΎΠ½Ρ–Ρ‚Ρƒ. Π‘ΡƒΡ‚Ρ‚Ρ”Π²ΠΎΠ³ΠΎ підвищСння СфСктивності вилучСння ΠΉΠΎΠ½Ρ–Π² ΠΌΡ–Π΄Ρ– Π½Π° Π΄Π°Π½ΠΎΠΌΡƒ ΠΊΠ°Ρ‚Ρ–ΠΎΠ½Ρ–Ρ‚Ρ– досягнуто Π² Π΄ΠΈΠ½Π°ΠΌΡ–Ρ‡Π½ΠΈΡ… ΡƒΠΌΠΎΠ²Π°Ρ… ΠΏΡ€ΠΈ використанні ΠΉΠΎΠ½Ρ–Ρ‚Ρƒ Π² кислій Ρ‚Π° ΡΠΎΠ»ΡŒΠΎΠ²Ρ–ΠΉ Ρ„ΠΎΡ€ΠΌΡ– Ρ– наявності Π² Ρ€ΠΎΠ·Ρ‡ΠΈΠ½Ρ– ΠΉΠΎΠ½Ρ–Π² Торсткості. ВстановлСно, Ρ‰ΠΎ Π΅Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½Ρ–ΡΡ‚ΡŒ дСсорбції ΠΉΠΎΠ½Ρ–Π² ΠΌΡ–Π΄Ρ– Ρ€ΠΎΠ·Ρ‡ΠΈΠ½Π°ΠΌΠΈ Ρ…Π»ΠΎΡ€ΠΈΠ΄Π½ΠΎΡ— кислоти Π² статичних ΡƒΠΌΠΎΠ²Π°Ρ… Π±ΡƒΠ»Π° низькою. Π’ Π΄ΠΈΠ½Π°ΠΌΡ–Ρ‡Π½ΠΈΡ… ΡƒΠΌΠΎΠ²Π°Ρ… досягнуто ΠΏΡ€Π°ΠΊΡ‚ΠΈΡ‡Π½ΠΎ ΠΏΠΎΠ²Π½ΠΎΠ³ΠΎ вилучСння ΠΉΠΎΠ½Ρ–Π² ΠΌΡ–Π΄Ρ– Ρ€ΠΎΠ·Ρ‡ΠΈΠ½Π°ΠΌΠΈ Ρ…Π»ΠΎΡ€ΠΈΠ΄Π½ΠΎΡ— кислоти.The results of studies to determine the effectiveness of KU-2-8 cation extracting copper ions from water hardness ions in the presence of low concentrations of copper ions. It is shown that at concentration of copper from 1 to 30 mg/dm3 extraction of copper takes place in static conditions inefficiently both from distilled and from tap water irrespective of an ionite form. This indicator decreases at increase in volume of solution at the fixed ionite volume. Significant efficiency removal of copper ions in this cation achieved in dynamic conditions using resin in acid and salt form in the presence of ions in solution stiffness. It was established that the efficiency of desorption of copper ions hydrochloric acid solutions in static conditions was low. In dynamic conditions reached almost complete desorption of copper ions by solutions of hydrochloric acid.ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ исслСдований ΠΏΠΎ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΡŽ эффСктивности ΠΊΠ°Ρ‚ΠΈΠΎΠ½ΠΈΡ‚Π° КУ-2-8 ΠΏΡ€ΠΈ ΠΈΠ·Π²Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ ΠΈΠ· Π²ΠΎΠ΄Ρ‹ Π² присутствии ΠΈΠΎΠ½ΠΎΠ² ТСсткости ΠΏΡ€ΠΈ Π½ΠΈΠ·ΠΊΠΈΡ… концСнтрациях ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ. Показано, Ρ‡Ρ‚ΠΎ Π² статичСских условиях ΠΏΡ€ΠΈ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ†ΠΈΠΈ ΠΌΠ΅Π΄ΠΈ ΠΎΡ‚ 1 Π΄ΠΎ 30 ΠΌΠ³/Π΄ΠΌ3 ΠΈΠ·Π²Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ ΠΌΠ΅Π΄ΠΈ ΠΏΡ€ΠΎΡ…ΠΎΠ΄ΠΈΡ‚ нСэффСктивно ΠΊΠ°ΠΊ ΠΈΠ· дистиллированной, Ρ‚Π°ΠΊ ΠΈ ΠΈΠ· Π²ΠΎΠ΄ΠΎΠΏΡ€ΠΎΠ²ΠΎΠ΄Π½ΠΎΠΉ Π²ΠΎΠ΄Ρ‹ нСзависимо ΠΎΡ‚ Ρ„ΠΎΡ€ΠΌΡ‹ ΠΈΠΎΠ½ΠΈΡ‚Π°. Π”Π°Π½Π½Ρ‹ΠΉ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΡŒ сниТаСтся ΠΏΡ€ΠΈ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠΈ объСма раствора ΠΏΡ€ΠΈ фиксированном объСмС ΠΈΠΎΠ½ΠΈΡ‚Π°. БущСствСнного ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΡ эффСктивности извлСчСния ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ Π½Π° Π΄Π°Π½Π½ΠΎΠΌ ΠΊΠ°Ρ‚ΠΈΠΎΠ½ΠΈΡ‚Π΅ достигнуто Π² динамичСских условиях ΠΏΡ€ΠΈ использовании ΠΈΠΎΠ½ΠΈΡ‚Π° Π² кислой ΠΈ солСвой Ρ„ΠΎΡ€ΠΌΠ΅ ΠΏΡ€ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠΈ Π² растворС ΠΈΠΎΠ½ΠΎΠ² ТСсткости. УстановлСно, Ρ‡Ρ‚ΠΎ ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ дСсорбции ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ растворами соляной кислоты Π² статичСских условиях Π±Ρ‹Π»Π° Π½ΠΈΠ·ΠΊΠΎΠΉ. Π’ динамичСских условиях достигнуто практичСски ΠΏΠΎΠ»Π½ΠΎΠΉ дСсорбции ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ растворами соляной кислоты

    On psychosemantics of notions "opinion", "knowledge", "belief"

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    Β© IAEME Publication. Currently the studies of particular relevance in which the ways of representation in the language of the subject's consciousness cognitive content, the characteristic properties of thinking verbal objectification and the basic thought features are analyzed. This article deals with the universal categories of knowledge, opinion and belief, largely structuring the cognitive, mental activity of a person, serving as the basic constructs in the subject's cognitive-evaluative activity. The paper presents the results of a series of our psychosemantic experiments, which made it possible to identify stable signs, cultural representations, associations that arise in the minds of native speakers in the actualization of categories of knowledge, opinion and belief and compare their content. Such experimental studies allow us to explicate the "hidden" mechanisms of verbalization of thought structures in the process of cognition of the world, to see what stands behind the word as a unit of the speech (linguistic) ability of the individual. The submitted data reflect the complex networks of relationships formed in conceptualization and categorization processes of the world

    Heart myxoma under the mask of interstitial lung lesion: a difficult case from practice

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    The aim of the investigation was to describe a clinical case of the development of interstitial lung lesions in a 57-year-old man with a large left atrial myxoma, which had a reverse development after myxomectomy.Materials and methods. Patient V., 57 years old, was hospitalized in the therapeutic department of the City Clinical Hospital No. 1 named after N. I. Pirogov in connection with bilateral polysegmental pneumonia. A month before hospitalization, he underwent an outpatient examination for progressive dyspnea. Myxoma of the heart was diagnosed. Due to the progression of respiratory failure and the appearance of fever, he was hospitalized. Amidst the multistage antibiotic therapy, there was a torpid course of lung pathology with syndromes of bilateral dissemination and β€œground glass”, bilateral lymphadenopathy of the mediastinum, high pulmonary hypertension, and systemic inflammatory reaction syndrome. Thromboembolism of the branches of the pulmonary artery, tuberculosis, sepsis, infective endocarditis, neoplastic processes of pulmonary and other localization were excluded.Results. The clinical picture corresponded to interstitial lung lesions within the framework of paraneoplastic syndrome in heart myxoma. It was decided to urgently carry out myxomectomy.Conclusion. The clinical case demonstrates the development of a rare variant of paraneoplastic syndrome in left atrial myxoma, which was suspected during the patient’s treatment for bilateral polysegmental pneumonia. The progression of the pulmonary lesion was explained by active interstitial inflammation and was supported by the immunological activity of the heart tumor.The performed myxomectomy, despite the persisting syndrome of systemic inflammatory reaction and infiltration of the lung tissue, led in 2 weeks to complete resolution of interstitial lung lesions and pulmonary hypertension, which confirmed the causal relationship between myxoma of the heart and involvement in the pathological process of the lungs

    Production technology of heat-resistant high-strength syntactic carbon foams for operation in extreme conditions

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    Β© Published under licence by IOP Publishing Ltd. Production technology of products based on the syntactic carbon foams designed to operate in extreme conditions is proposed. The components and regime parameters for the production of foams of an open-pore cellular structure with specified thermophysical and strength characteristics for manufacturing the large-sized products of complex shape are determined

    Impact of Honeybee Venom Melittin on Cell Viability of Different Prostate Cancer Lineages

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    Background. Melittin is a major constituent of honeybee venom and comprises a water-soluble surfactant peptide with cytolytic effects potentially applicable in anticancer therapy. We evaluated the impact of melittin from Bashkir honeybee (Apis mellifera mellifera L.) venom on cell viability of various prostate cancer lineages.Materials and methods. MTT assays with cell viability index estimation were used to evaluate the effect of melittin on cell proliferation in various-grade malignancy prostate cancer (PC) lineages, LNCaP, PC-3 and DU145.Results and discussion. Lineage DU145 revealed a low sensitivity to melittin, because a relatively high peptide concentration of 10 ΞΌg/mL had a suppressive effect on its proliferation. With PC-3 cells, a 0.1 ΞΌg/mL concentration suppressed proliferation significantly to 46.15 %, while melittin at a 10 ΞΌg/mL dose had a cytolytic effect on most cells (4.27 % viability). LNCaP cells experienced the lowest toxicity at 10 ΞΌg/mL melittin compared to PC-3 and DU145 lineages. The LNCaP, PC-3 and DU145 PC lineages demonstrated suppressed proliferation at melittin levels 0.01–100 ΞΌg/mL.Conclusion. The study reveals a significant reduction of the PC lineages viability at a minimal melittin concentration of 0.01 ΞΌg/mL, which indicates a high cytolytic activity of this peptide and renders it a candidate agent in antitumour therapy

    The estimation of subjective sensations in the oral cavity in children with chronic renal insufficiency under hemodialysis

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    The estimation of subjective sensations in the oral cavity in children with chronic renal insufficiency under hemodialysis has been carried out that revealed the efficacy of application after hemodialysis of chewing phytosubstrate based on Archangelica Officinalis Hoffm radix and bee wax in prevention and treatment of dental diseases in children with chronic renal insufficiency under hemodialysis has been estimated. Reduction in the dryness of mucous membrane of the lips and oral cavity, gingival bleeding and burning sensation have been clinically revealed. The supposed method of prevention and treatment of dental diseases in children with chronic renal insufficiency under hemodialysis can be applied in the complex treatment of the present group of patients.ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π° ΠΎΡ†Π΅Π½ΠΊΠ° ΡΡƒΠ±ΡŠΠ΅ΠΊΡ‚ΠΈΠ²Π½Ρ‹Ρ… ΠΎΡ‰ΡƒΡ‰Π΅Π½ΠΈΠΉ Π² полости Ρ€Ρ‚Π°, которая ΠΏΠΎΠΊΠ°Π·Π°Π»Π° ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ примСнСния послС Π³Π΅ΠΌΠΎΠ΄ΠΈΠ°Π»ΠΈΠ·Π°, ΠΆΠ΅Π²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ Ρ„ΠΈΡ‚ΠΎ-субстрата Π½Π° основС экстракта корня дягиля лСкарствСнного (Archangelica officinalis Hoffm) ΠΈ ΠΏΡ‡Π΅Π»ΠΈΠ½ΠΎΠ³ΠΎ воска Π² комплСксной ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΠΊΠ΅ ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ стоматологичСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ Ρƒ Π΄Π΅Ρ‚Π΅ΠΉ с хроничСской ΠΏΠΎΡ‡Π΅Ρ‡Π½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡ‚Π°Ρ‚ΠΎΡ‡Π½ΠΎΡΡ‚ΡŒΡŽ, находящихся Π½Π° Π³Π΅ΠΌΠΎΠ΄ΠΈΠ°Π»ΠΈΠ·Π΅. ΠšΠ»ΠΈΠ½ΠΈΡ‡Π΅ΡΠΊΠΈ ΠΎΡ‚ΠΌΠ΅Ρ‡Π΅Π½ΠΎ ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ сухости слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ красной ΠΊΠ°ΠΉΠΌΡ‹ Π³ΡƒΠ± ΠΈ слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ полости Ρ€Ρ‚Π°, кровоточивости дСсСн ΠΈ чувства ТТСния Π² полости Ρ€Ρ‚Π°. ΠŸΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Π½Ρ‹ΠΉ ΠΌΠ΅Ρ‚ΠΎΠ΄ ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΠΊΠΈ ΠΈ лСчСния стоматологичСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ Ρƒ Π΄Π΅Ρ‚Π΅ΠΉ с Π₯ПН, находящихся Π½Π° Π³Π΅ΠΌΠΎΠ΄ΠΈΠ°Π»ΠΈΠ·Π΅ ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ использован Π² комплСксС Π»Π΅Ρ‡Π΅Π±Π½Ρ‹Ρ… мСроприятий Ρƒ Π΄Π°Π½Π½ΠΎΠΉ Π³Ρ€ΡƒΠΏΠΏΡ‹ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…

    Бвязь курСния с ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠΉ болСзнью сСрдца Π² зависимости ΠΎΡ‚ Π΄Ρ€ΡƒΠ³ΠΈΡ… Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² сСрдСчно-сосудистого риска

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    Β Aim. To study the possibility of the presence of coronary artery disease (CAD) depending on the smoking status, as well as to estimate the association of smoking with other traditional risk factors in residents of Kemerovo region aged 25–64 years.Materials and methods. We analyzed the results of the multicenter epidemiological study β€œEpidemiology of cardiovascular diseases and their risk factors in the Russian Federation” in Kemerovo region obtained from a random sample of 1,599 subjects aged 25–64 years. Besides the smoking status, the following parameters were analyzed: gender, age, education, diabetes mellitus (DM) and arterial hypertension (AH) history, hypercholesterolemia, hypertriglyceridemia, high level of low-density lipoproteins, low level of high-density lipoproteins (HDL), hyperglycemia, obesity, alcohol abuse, and depression.Results. Three groups were formed depending on the smoking status: group 1 included 484 (30.3%) current smokers, group 2 had 317 (19.8%) former smokers and group 3 had 798 (49.9%) individuals who had never smoked. The groups did not differ in the prevalence of CAD. When determining the rank significance of the impact of risk factors on the possibility of CAD development in the overall population, it was revealed that the age affected the risk of CAD the most, while smoking and low HDL had minimal impact.Β  The impact of the smoking factor on CAD was higher in the representatives of the older age group; however, even in the subjects aged β‰₯ 50 years,the smoking factor was not the leading one and followed DM,Β  hypertriglyceridemia, depression, and obesity. The possibility of CAD development in smokers, as opposed to individuals who had never smoked, increased when smoking was accompanied by hypercholesterolemia, hypertriglyceridemia, male sex, lack of higher education, depression, and age of β‰₯ 50 years. The possibility of CAD development in former smokers as opposed to nonsmokers increased when smoking was accompanied by hyperglycemia.Conclusion. Smoking is not the primary risk factor in CAD detection in the studied sample. In the presence of additional risk factors, the impact of smoking on the possibility of CAD detection increases.   ЦСль. Π˜Π·ΡƒΡ‡Π΅Π½ΠΈΠ΅ вСроятности наличия ΠΈΡˆΠ΅ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΠΈ сСрдца (Π˜Π‘Π‘) Π² зависимости ΠΎΡ‚ статуса курСния, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΎΡ†Π΅Π½ΠΊΠ° связи курСния с Π΄Ρ€ΡƒΠ³ΠΈΠΌΠΈ Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½Ρ‹ΠΌΠΈ Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌΠΈ риска Ρƒ ΠΆΠΈΡ‚Π΅Π»Π΅ΠΉ ΠšΡƒΠ·Π±Π°ΡΡΠΊΠΎΠ³ΠΎ Ρ€Π΅Π³ΠΈΠΎΠ½Π° Π² возрастС 25–64 Π»Π΅Ρ‚.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠ²Β  ΠΌΠ½ΠΎΠ³ΠΎΡ†Π΅Π½Ρ‚Ρ€ΠΎΠ²ΠΎΠ³ΠΎ эпидСмиологичСского исслСдования «ЭпидСмиология сСрдСчно-сосудистых Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΈΡ…Β  Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² риска Π² Российской Π€Π΅Π΄Π΅Ρ€Π°Ρ†ΠΈΠΈΒ» Π² ΠšΠ΅ΠΌΠ΅Ρ€ΠΎΠ²ΡΠΊΠΎΠΉ области, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Ρ… Π½Π° случайной Π²Ρ‹Π±ΠΎΡ€ΠΊΠ΅ 1 599 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ Π² возрастС 25–64 Π»Π΅Ρ‚. Помимо статуса курСния Π°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π»ΠΈΡΡŒ ΠΏΠΎΠ», возраст, ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Π½ΠΈΠ΅, Π½Π°Π»ΠΈΡ‡ΠΈΠ΅Β  сахарного Π΄ΠΈΠ°Π±Π΅Ρ‚Π° (Π‘Π”) ΠΈ Π°Ρ€Ρ‚Π΅Ρ€ΠΈΠ°Π»ΡŒΠ½Π°Ρ гипСртСнзия,Β  гипСрхолСстСринСмия, гипСртриглицСридСмия, высокий  ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π»ΠΈΠΏΠΎΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ΄ΠΎΠ² Π½ΠΈΠ·ΠΊΠΎΠΉ плотности, Π½ΠΈΠ·ΠΊΠΈΠΉ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒΒ  Π»ΠΈΠΏΠΎΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ΄ΠΎΠ² высокой плотности (Π›ΠŸΠ’ΠŸ), гипСргликСмия,Β  ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΠ΅, Π·Π»ΠΎΡƒΠΏΠΎΡ‚Ρ€Π΅Π±Π»Π΅Π½ΠΈΠ΅ Π°Π»ΠΊΠΎΠ³ΠΎΠ»Π΅ΠΌ ΠΈ дСпрСссия.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Π’ зависимости ΠΎΡ‚ статуса курСния  сформированы Ρ‚Ρ€ΠΈ Π³Ρ€ΡƒΠΏΠΏΡ‹. ΠŸΠ΅Ρ€Π²Π°Ρ Π³Ρ€ΡƒΠΏΠΏΠ° – курящиС Π²Β  настоящСС врСмя, 484 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊΠ° (30,3%), вторая – ΠΊΡƒΡ€ΠΈΠ²ΡˆΠΈΠ΅ Π²Β  ΠΏΡ€ΠΎΡˆΠ»ΠΎΠΌ, 317 (19,8%), ΠΈ Ρ‚Ρ€Π΅Ρ‚ΡŒΡ Π³Ρ€ΡƒΠΏΠΏΠ° – Π½ΠΈΠΊΠΎΠ³Π΄Π° Π½Π΅ ΠΊΡƒΡ€ΠΈΠ²ΡˆΠΈΠ΅, 798 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ (49,9%). Π“Ρ€ΡƒΠΏΠΏΡ‹ Π½Π΅ ΠΈΠΌΠ΅Π»ΠΈ Ρ€Π°Π·Π»ΠΈΡ‡ΠΈΠΉΒ  ΠΏΠΎ распространСнности Π˜Π‘Π‘. ΠŸΡ€ΠΈ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠΈ Ρ€Π°Π½Π³ΠΎΠ²ΠΎΠΉΒ  значимости влияния Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² риска Π½Π° Π²Π΅Ρ€ΠΎΡΡ‚Π½ΠΎΡΡ‚ΡŒ Π˜Π‘Π‘ Π²Β  ΠΎΠ±Ρ‰Π΅ΠΉ популяции выявлСно, Ρ‡Ρ‚ΠΎ возраст являСтся самым ΡΠΈΠ»ΡŒΠ½Ρ‹ΠΌ Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠΌ, Π° ΠΊΡƒΡ€Π΅Π½ΠΈΠ΅ ΠΈ Π½ΠΈΠ·ΠΊΠΈΠΉ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π›ΠŸΠ’ΠŸ –  ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡŒΠ½Ρ‹ΠΌΠΈ. Π‘Ρ‚Π΅ΠΏΠ΅Π½ΡŒ влияния Π½Π° Π˜Π‘Π‘ Ρ„Π°ΠΊΡ‚ΠΎΡ€Π° курСния Π²Ρ‹ΡˆΠ΅ Ρƒ прСдставитСлСй ΡΡ‚Π°Ρ€ΡˆΠ΅ΠΉ возрастной Π³Ρ€ΡƒΠΏΠΏΡ‹, ΠΎΠ΄Π½Π°ΠΊΠΎΠ΄Π°ΠΆΠ΅ Ρƒ Π»ΠΈΡ† Π² возрастС 50 Π»Π΅Ρ‚ ΠΈ ΡΡ‚Π°Ρ€ΡˆΠ΅ Ρ„Π°ΠΊΡ‚ курСния Π½Π΅ занял  Π»ΠΈΠ΄ΠΈΡ€ΡƒΡŽΡ‰ΠΈΠ΅ ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΈ ΠΈ слСдовал Π·Π° Π‘Π”, Π³ΠΈΠΏΠ΅Ρ€Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄Π΅ΠΌΠΈΠ΅ΠΉ, дСпрСссиСй ΠΈ ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΠ΅ΠΌ. Π’Π΅Ρ€ΠΎΡΡ‚Π½ΠΎΡΡ‚ΡŒ Π˜Π‘Π‘ Ρƒ курящих Π² сравнСнии с Π½ΠΈΠΊΠΎΠ³Π΄Π° Π½Π΅ ΠΊΡƒΡ€ΠΈΠ²ΡˆΠΈΠΌΠΈ усиливаСтся ΠΏΡ€ΠΈ сочСтании курСния с  гипСрхолСстСринСмиСй, Π³ΠΈΠΏΠ΅Ρ€Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄Π΅ΠΌΠΈΠ΅ΠΉ, муТским ΠΏΠΎΠ»ΠΎΠΌ, отсутствиСм Π²Ρ‹ΡΡˆΠ΅Π³ΠΎ образования, Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ΠΌΒ  дСпрСссии ΠΈ возрастом 50 Π»Π΅Ρ‚ ΠΈ ΡΡ‚Π°Ρ€ΡˆΠ΅. Π£ ΠΊΡƒΡ€ΠΈΠ²ΡˆΠΈΡ… Π² ΠΏΡ€ΠΎΡˆΠ»ΠΎΠΌ ΠΊ Π½Π΅ курящим – ΠΏΡ€ΠΈ сочСтании с Π³ΠΈΠΏΠ΅Ρ€Π³Π»ΠΈΠΊΠ΅ΠΌΠΈΠ΅ΠΉ.Β Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. ΠšΡƒΡ€Π΅Π½ΠΈΠ΅ являСтся Π½Π΅ пСрвостСпСнным  Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠΌ риска ΠΏΡ€ΠΈ выявлСнии Π˜Π‘Π‘ Π² исслСдуСмой Π²Ρ‹Π±ΠΎΡ€ΠΊΠ΅, Π° ΠΏΡ€ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠΈ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² риска  влияниС курСния Π½Π° Π²Π΅Ρ€ΠΎΡΡ‚Π½ΠΎΡΡ‚ΡŒ выявлСния Π˜Π‘Π‘ усиливаСтся.
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