67 research outputs found
Tree Stands and Their Productivity Dynamics at the Upper Growing Limit in Khibiny on the Background of Modern Climate Changes
Within the ecotone of the upper limit of woody vegetation on the southeastern macroslope of the Khibiny Mountain ridge (Kola Peninsula), the spatial and age structure, as well as features of the phytomass accumulation of spruceβbirch stands, were studied. Analysis revealed that there was a manifold increase in the density and productivity of forest stands in the last century, and the upper border of the woodlands and dense forests has moved considerably higher into the mountains. All of this happened against the background of an increase in early summer temperatures and a longer growing season in the area in the 20th century. Our data will help simulate the response of mountain ecosystems in the region to future climate change. Β© 2019, Pleiades Publishing, Ltd
Structure and Dynamics of Tree Stands at the Upper Timberline in the Western Part of the Putorana Plateau
Analysis of the age structure of Dahurian larch (Larix gmelinii Rupr.) forests in the western part of the Putorana Plateau (Sukhie Gory Range) and comparison of diachronous topographic maps and satellite images have revealed changes in the altitudinal position of the upper boundary of tree vegetation. the most significant changes occurred on south- and southwest-facing slopes. Correlations of trunk diameters with the phytomass of trees and its fractions have been found. the course of changes in the structure and phytomass of tree stands in the upper timberline over the past centuries has been reconstructed. Forest expansion has been facilitated by the general change in climate conditions (warming) in the study area.This study was supported by the Russian Science Foundation, project no. 17-14-01112
Effect of propolis bioflavonoids on the antioxidant potential of ejaculate and on oxidative sperm DNA damage
The investigation was undertaken to assess the molecular mechanisms of antioxidant action of propolis bioflavonoids in pathospermia. It included the data of examining 75 infertile males and 36 fertile ones. The 3-month administration of the agent in a daily dose of 40 mg resulted in normalization of ejaculate parameters, a reduction in the levels of biomarkers for oxidative protein and sperm DNA damage, and recovery of the antioxidant status of seminal plasma.</em
ΠΡΠ΅Π½ΠΊΠ° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΠ°ΡΠΈΠΎΠ½ΠΈΡΠ° ΠΠ£-2-8 ΠΏΡΠΈ ΠΈΠ·Π²Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ ΠΈΠ· Π²ΠΎΠ΄Ρ Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΆΠ΅ΡΡΠΊΠΎΡΡΠΈ
ΠΠ°Π²Π΅Π΄Π΅Π½ΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΈ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Ρ Π· Π²ΠΈΠ·Π½Π°ΡΠ΅Π½Π½Ρ Π΅ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΠ°ΡΡΠΎΠ½ΡΡΡ ΠΠ£-2-8 ΠΏΡΠ΄ ΡΠ°Ρ Π²ΠΈΠ»ΡΡΠ΅Π½Π½Ρ ΠΉΠΎΠ½ΡΠ² ΠΌΡΠ΄Ρ Π· Π²ΠΎΠ΄ΠΈ Π² ΠΏΡΠΈΡΡΡΠ½ΠΎΡΡΡ ΠΉΠΎΠ½ΡΠ² ΠΆΠΎΡΡΡΠΊΠΎΡΡΡ Π·Π° Π½ΠΈΠ·ΡΠΊΠΈΡ
ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΡΠΉ ΠΉΠΎΠ½ΡΠ² ΠΌΡΠ΄Ρ. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΠΎ Π² ΡΡΠ°ΡΠΈΡΠ½ΠΈΡ
ΡΠΌΠΎΠ²Π°Ρ
ΠΏΡΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΡΡ ΠΌΡΠ΄Ρ Π²ΡΠ΄ 1 Π΄ΠΎ 30 ΠΌΠ³/Π΄ΠΌ3 Π²ΠΈΠ»ΡΡΠ΅Π½Π½Ρ ΠΌΡΠ΄Ρ ΠΏΡΠΎΡ
ΠΎΠ΄ΠΈΡΡ Π½Π΅Π΅ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΡΠΊ Π· Π΄ΠΈΡΡΠΈΠ»ΡΠΎΠ²Π°Π½ΠΎΡ, ΡΠ°ΠΊ Ρ Π· Π²ΠΎΠ΄ΠΎΠΏΡΠΎΠ²ΡΠ΄Π½ΠΎΡ Π²ΠΎΠ΄ΠΈ Π½Π΅Π·Π°Π»Π΅ΠΆΠ½ΠΎ Π²ΡΠ΄ ΡΠΎΡΠΌΠΈ ΠΉΠΎΠ½ΡΡΡ. ΠΠ°Π½ΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊ Π·Π½ΠΈΠΆΡΡΡΡΡΡ ΠΏΡΠ΄ ΡΠ°Ρ Π·Π±ΡΠ»ΡΡΠ΅Π½Π½Ρ ΠΎΠ±βΡΠΌΡ ΡΠΎΠ·ΡΠΈΠ½Ρ ΠΏΡΠΈ ΡΡΠΊΡΠΎΠ²Π°Π½ΠΎΠΌΡ ΠΎΠ±βΡΠΌΡ ΠΉΠΎΠ½ΡΡΡ. Π‘ΡΡΡΡΠ²ΠΎΠ³ΠΎ ΠΏΡΠ΄Π²ΠΈΡΠ΅Π½Π½Ρ Π΅ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π²ΠΈΠ»ΡΡΠ΅Π½Π½Ρ ΠΉΠΎΠ½ΡΠ² ΠΌΡΠ΄Ρ Π½Π° Π΄Π°Π½ΠΎΠΌΡ ΠΊΠ°ΡΡΠΎΠ½ΡΡΡ Π΄ΠΎΡΡΠ³Π½ΡΡΠΎ Π² Π΄ΠΈΠ½Π°ΠΌΡΡΠ½ΠΈΡ
ΡΠΌΠΎΠ²Π°Ρ
ΠΏΡΠΈ Π²ΠΈΠΊΠΎΡΠΈΡΡΠ°Π½Π½Ρ ΠΉΠΎΠ½ΡΡΡ Π² ΠΊΠΈΡΠ»ΡΠΉ ΡΠ° ΡΠΎΠ»ΡΠΎΠ²ΡΠΉ ΡΠΎΡΠΌΡ Ρ Π½Π°ΡΠ²Π½ΠΎΡΡΡ Π² ΡΠΎΠ·ΡΠΈΠ½Ρ ΠΉΠΎΠ½ΡΠ² ΠΆΠΎΡΡΡΠΊΠΎΡΡΡ. ΠΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΠΎ Π΅ΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡΡΡ Π΄Π΅ΡΠΎΡΠ±ΡΡΡ ΠΉΠΎΠ½ΡΠ² ΠΌΡΠ΄Ρ ΡΠΎΠ·ΡΠΈΠ½Π°ΠΌΠΈ Ρ
Π»ΠΎΡΠΈΠ΄Π½ΠΎΡ ΠΊΠΈΡΠ»ΠΎΡΠΈ Π² ΡΡΠ°ΡΠΈΡΠ½ΠΈΡ
ΡΠΌΠΎΠ²Π°Ρ
Π±ΡΠ»Π° Π½ΠΈΠ·ΡΠΊΠΎΡ. Π Π΄ΠΈΠ½Π°ΠΌΡΡΠ½ΠΈΡ
ΡΠΌΠΎΠ²Π°Ρ
Π΄ΠΎΡΡΠ³Π½ΡΡΠΎ ΠΏΡΠ°ΠΊΡΠΈΡΠ½ΠΎ ΠΏΠΎΠ²Π½ΠΎΠ³ΠΎ Π²ΠΈΠ»ΡΡΠ΅Π½Π½Ρ ΠΉΠΎΠ½ΡΠ² ΠΌΡΠ΄Ρ ΡΠΎΠ·ΡΠΈΠ½Π°ΠΌΠΈ Ρ
Π»ΠΎΡΠΈΠ΄Π½ΠΎΡ ΠΊΠΈΡΠ»ΠΎΡΠΈ.The results of studies to determine the effectiveness of KU-2-8 cation extracting copper ions from water hardness ions in the presence of low concentrations of copper ions. It is shown that at concentration of copper from 1 to 30 mg/dm3 extraction of copper takes place in static conditions inefficiently both from distilled and from tap water irrespective of an ionite form. This indicator decreases at increase in volume of solution at the fixed ionite volume. Significant efficiency removal of copper ions in this cation achieved in dynamic conditions using resin in acid and salt form in the presence of ions in solution stiffness. It was established that the efficiency of desorption of copper ions hydrochloric acid solutions in static conditions was low. In dynamic conditions reached almost complete desorption of copper ions by solutions of hydrochloric acid.ΠΡΠΈΠ²Π΅Π΄Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΠΏΠΎ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΠ°ΡΠΈΠΎΠ½ΠΈΡΠ° ΠΠ£-2-8 ΠΏΡΠΈ ΠΈΠ·Π²Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ ΠΈΠ· Π²ΠΎΠ΄Ρ Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΆΠ΅ΡΡΠΊΠΎΡΡΠΈ ΠΏΡΠΈ Π½ΠΈΠ·ΠΊΠΈΡ
ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡΡ
ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π² ΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΠΏΡΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΠΌΠ΅Π΄ΠΈ ΠΎΡ 1 Π΄ΠΎ 30 ΠΌΠ³/Π΄ΠΌ3 ΠΈΠ·Π²Π»Π΅ΡΠ΅Π½ΠΈΠ΅ ΠΌΠ΅Π΄ΠΈ ΠΏΡΠΎΡ
ΠΎΠ΄ΠΈΡ Π½Π΅ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΊΠ°ΠΊ ΠΈΠ· Π΄ΠΈΡΡΠΈΠ»Π»ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ, ΡΠ°ΠΊ ΠΈ ΠΈΠ· Π²ΠΎΠ΄ΠΎΠΏΡΠΎΠ²ΠΎΠ΄Π½ΠΎΠΉ Π²ΠΎΠ΄Ρ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΠΎ ΠΎΡ ΡΠΎΡΠΌΡ ΠΈΠΎΠ½ΠΈΡΠ°. ΠΠ°Π½Π½ΡΠΉ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Ρ ΡΠ½ΠΈΠΆΠ°Π΅ΡΡΡ ΠΏΡΠΈ ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠΈ ΠΎΠ±ΡΠ΅ΠΌΠ° ΡΠ°ΡΡΠ²ΠΎΡΠ° ΠΏΡΠΈ ΡΠΈΠΊΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌ ΠΎΠ±ΡΠ΅ΠΌΠ΅ ΠΈΠΎΠ½ΠΈΡΠ°. Π‘ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈΠ·Π²Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ Π½Π° Π΄Π°Π½Π½ΠΎΠΌ ΠΊΠ°ΡΠΈΠΎΠ½ΠΈΡΠ΅ Π΄ΠΎΡΡΠΈΠ³Π½ΡΡΠΎ Π² Π΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΠΏΡΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΠΎΠ½ΠΈΡΠ° Π² ΠΊΠΈΡΠ»ΠΎΠΉ ΠΈ ΡΠΎΠ»Π΅Π²ΠΎΠΉ ΡΠΎΡΠΌΠ΅ ΠΏΡΠΈ Π½Π°Π»ΠΈΡΠΈΠΈ Π² ΡΠ°ΡΡΠ²ΠΎΡΠ΅ ΠΈΠΎΠ½ΠΎΠ² ΠΆΠ΅ΡΡΠΊΠΎΡΡΠΈ. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π΄Π΅ΡΠΎΡΠ±ΡΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ ΡΠ°ΡΡΠ²ΠΎΡΠ°ΠΌΠΈ ΡΠΎΠ»ΡΠ½ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ Π² ΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
Π±ΡΠ»Π° Π½ΠΈΠ·ΠΊΠΎΠΉ. Π Π΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
Π΄ΠΎΡΡΠΈΠ³Π½ΡΡΠΎ ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈ ΠΏΠΎΠ»Π½ΠΎΠΉ Π΄Π΅ΡΠΎΡΠ±ΡΠΈΠΈ ΠΈΠΎΠ½ΠΎΠ² ΠΌΠ΅Π΄ΠΈ ΡΠ°ΡΡΠ²ΠΎΡΠ°ΠΌΠΈ ΡΠΎΠ»ΡΠ½ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ
On psychosemantics of notions "opinion", "knowledge", "belief"
Β© IAEME Publication. Currently the studies of particular relevance in which the ways of representation in the language of the subject's consciousness cognitive content, the characteristic properties of thinking verbal objectification and the basic thought features are analyzed. This article deals with the universal categories of knowledge, opinion and belief, largely structuring the cognitive, mental activity of a person, serving as the basic constructs in the subject's cognitive-evaluative activity. The paper presents the results of a series of our psychosemantic experiments, which made it possible to identify stable signs, cultural representations, associations that arise in the minds of native speakers in the actualization of categories of knowledge, opinion and belief and compare their content. Such experimental studies allow us to explicate the "hidden" mechanisms of verbalization of thought structures in the process of cognition of the world, to see what stands behind the word as a unit of the speech (linguistic) ability of the individual. The submitted data reflect the complex networks of relationships formed in conceptualization and categorization processes of the world
Heart myxoma under the mask of interstitial lung lesion: a difficult case from practice
The aim of the investigation was to describe a clinical case of the development of interstitial lung lesions in a 57-year-old man with a large left atrial myxoma, which had a reverse development after myxomectomy.Materials and methods. Patient V., 57 years old, was hospitalized in the therapeutic department of the City Clinical Hospital No. 1 named after N. I. Pirogov in connection with bilateral polysegmental pneumonia. A month before hospitalization, he underwent an outpatient examination for progressive dyspnea. Myxoma of the heart was diagnosed. Due to the progression of respiratory failure and the appearance of fever, he was hospitalized. Amidst the multistage antibiotic therapy, there was a torpid course of lung pathology with syndromes of bilateral dissemination and βground glassβ, bilateral lymphadenopathy of the mediastinum, high pulmonary hypertension, and systemic inflammatory reaction syndrome. Thromboembolism of the branches of the pulmonary artery, tuberculosis, sepsis, infective endocarditis, neoplastic processes of pulmonary and other localization were excluded.Results. The clinical picture corresponded to interstitial lung lesions within the framework of paraneoplastic syndrome in heart myxoma. It was decided to urgently carry out myxomectomy.Conclusion. The clinical case demonstrates the development of a rare variant of paraneoplastic syndrome in left atrial myxoma, which was suspected during the patientβs treatment for bilateral polysegmental pneumonia. The progression of the pulmonary lesion was explained by active interstitial inflammation and was supported by the immunological activity of the heart tumor.The performed myxomectomy, despite the persisting syndrome of systemic inflammatory reaction and infiltration of the lung tissue, led in 2 weeks to complete resolution of interstitial lung lesions and pulmonary hypertension, which confirmed the causal relationship between myxoma of the heart and involvement in the pathological process of the lungs
Production technology of heat-resistant high-strength syntactic carbon foams for operation in extreme conditions
Β© Published under licence by IOP Publishing Ltd. Production technology of products based on the syntactic carbon foams designed to operate in extreme conditions is proposed. The components and regime parameters for the production of foams of an open-pore cellular structure with specified thermophysical and strength characteristics for manufacturing the large-sized products of complex shape are determined
Impact of Honeybee Venom Melittin on Cell Viability of Different Prostate Cancer Lineages
Background. Melittin is a major constituent of honeybee venom and comprises a water-soluble surfactant peptide with cytolytic effects potentially applicable in anticancer therapy. We evaluated the impact of melittin from Bashkir honeybee (Apis mellifera mellifera L.) venom on cell viability of various prostate cancer lineages.Materials and methods. MTT assays with cell viability index estimation were used to evaluate the effect of melittin on cell proliferation in various-grade malignancy prostate cancer (PC) lineages, LNCaP, PC-3 and DU145.Results and discussion. Lineage DU145 revealed a low sensitivity to melittin, because a relatively high peptide concentration of 10 ΞΌg/mL had a suppressive effect on its proliferation. With PC-3 cells, a 0.1 ΞΌg/mL concentration suppressed proliferation significantly to 46.15 %, while melittin at a 10 ΞΌg/mL dose had a cytolytic effect on most cells (4.27 % viability). LNCaP cells experienced the lowest toxicity at 10 ΞΌg/mL melittin compared to PC-3 and DU145 lineages. The LNCaP, PC-3 and DU145 PC lineages demonstrated suppressed proliferation at melittin levels 0.01β100 ΞΌg/mL.Conclusion. The study reveals a significant reduction of the PC lineages viability at a minimal melittin concentration of 0.01 ΞΌg/mL, which indicates a high cytolytic activity of this peptide and renders it a candidate agent in antitumour therapy
The estimation of subjective sensations in the oral cavity in children with chronic renal insufficiency under hemodialysis
The estimation of subjective sensations in the oral cavity in children with chronic renal insufficiency under hemodialysis has been carried out that revealed the efficacy of application after hemodialysis of chewing phytosubstrate based on Archangelica Officinalis Hoffm radix and bee wax in prevention and treatment of dental diseases in children with chronic renal insufficiency under hemodialysis has been estimated. Reduction in the dryness of mucous membrane of the lips and oral cavity, gingival bleeding and burning sensation have been clinically revealed. The supposed method of prevention and treatment of dental diseases in children with chronic renal insufficiency under hemodialysis can be applied in the complex treatment of the present group of patients.ΠΡΠΎΠ²Π΅Π΄Π΅Π½Π° ΠΎΡΠ΅Π½ΠΊΠ° ΡΡΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΠΎΡΡΡΠ΅Π½ΠΈΠΉ Π² ΠΏΠΎΠ»ΠΎΡΡΠΈ ΡΡΠ°, ΠΊΠΎΡΠΎΡΠ°Ρ ΠΏΠΎΠΊΠ°Π·Π°Π»Π° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΏΠΎΡΠ»Π΅ Π³Π΅ΠΌΠΎΠ΄ΠΈΠ°Π»ΠΈΠ·Π°, ΠΆΠ΅Π²Π°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΈΡΠΎ-ΡΡΠ±ΡΡΡΠ°ΡΠ° Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΊΡΡΡΠ°ΠΊΡΠ° ΠΊΠΎΡΠ½Ρ Π΄ΡΠ³ΠΈΠ»Ρ Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ (Archangelica officinalis Hoffm) ΠΈ ΠΏΡΠ΅Π»ΠΈΠ½ΠΎΠ³ΠΎ Π²ΠΎΡΠΊΠ° Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠ΅ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ Ρ Π΄Π΅ΡΠ΅ΠΉ Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΠ΅ΡΠ½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΡΡ, Π½Π°Ρ
ΠΎΠ΄ΡΡΠΈΡ
ΡΡ Π½Π° Π³Π΅ΠΌΠΎΠ΄ΠΈΠ°Π»ΠΈΠ·Π΅. ΠΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈ ΠΎΡΠΌΠ΅ΡΠ΅Π½ΠΎ ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΡ
ΠΎΡΡΠΈ ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠΈ ΠΊΡΠ°ΡΠ½ΠΎΠΉ ΠΊΠ°ΠΉΠΌΡ Π³ΡΠ± ΠΈ ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠΈ ΠΏΠΎΠ»ΠΎΡΡΠΈ ΡΡΠ°, ΠΊΡΠΎΠ²ΠΎΡΠΎΡΠΈΠ²ΠΎΡΡΠΈ Π΄Π΅ΡΠ΅Π½ ΠΈ ΡΡΠ²ΡΡΠ²Π° ΠΆΠΆΠ΅Π½ΠΈΡ Π² ΠΏΠΎΠ»ΠΎΡΡΠΈ ΡΡΠ°. ΠΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Π½ΡΠΉ ΠΌΠ΅ΡΠΎΠ΄ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠΈ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ Ρ Π΄Π΅ΡΠ΅ΠΉ Ρ Π₯ΠΠ, Π½Π°Ρ
ΠΎΠ΄ΡΡΠΈΡ
ΡΡ Π½Π° Π³Π΅ΠΌΠΎΠ΄ΠΈΠ°Π»ΠΈΠ·Π΅ ΠΌΠΎΠΆΠ΅Ρ Π±ΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ΅ Π»Π΅ΡΠ΅Π±Π½ΡΡ
ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΠΉ Ρ Π΄Π°Π½Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π±ΠΎΠ»ΡΠ½ΡΡ
Π‘Π²ΡΠ·Ρ ΠΊΡΡΠ΅Π½ΠΈΡ Ρ ΠΈΡΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΡΡ ΡΠ΅ΡΠ΄ΡΠ° Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ Π΄ΡΡΠ³ΠΈΡ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ°
Β Aim. To study the possibility of the presence of coronary artery disease (CAD) depending on the smoking status, as well as to estimate the association of smoking with other traditional risk factors in residents of Kemerovo region aged 25β64 years.Materials and methods. We analyzed the results of the multicenter epidemiological study βEpidemiology of cardiovascular diseases and their risk factors in the Russian Federationβ in Kemerovo region obtained from a random sample of 1,599 subjects aged 25β64 years. Besides the smoking status, the following parameters were analyzed: gender, age, education, diabetes mellitus (DM) and arterial hypertension (AH) history, hypercholesterolemia, hypertriglyceridemia, high level of low-density lipoproteins, low level of high-density lipoproteins (HDL), hyperglycemia, obesity, alcohol abuse, and depression.Results. Three groups were formed depending on the smoking status: group 1 included 484 (30.3%) current smokers, group 2 had 317 (19.8%) former smokers and group 3 had 798 (49.9%) individuals who had never smoked. The groups did not differ in the prevalence of CAD. When determining the rank significance of the impact of risk factors on the possibility of CAD development in the overall population, it was revealed that the age affected the risk of CAD the most, while smoking and low HDL had minimal impact.Β The impact of the smoking factor on CAD was higher in the representatives of the older age group; however, even in the subjects aged β₯ 50 years,the smoking factor was not the leading one and followed DM,Β hypertriglyceridemia, depression, and obesity. The possibility of CAD development in smokers, as opposed to individuals who had never smoked, increased when smoking was accompanied by hypercholesterolemia, hypertriglyceridemia, male sex, lack of higher education, depression, and age of β₯ 50 years. The possibility of CAD development in former smokers as opposed to nonsmokers increased when smoking was accompanied by hyperglycemia.Conclusion. Smoking is not the primary risk factor in CAD detection in the studied sample. In the presence of additional risk factors, the impact of smoking on the possibility of CAD detection increases. Β Β Π¦Π΅Π»Ρ. ΠΠ·ΡΡΠ΅Π½ΠΈΠ΅ Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΠΈ Π½Π°Π»ΠΈΡΠΈΡ ΠΈΡΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΡΠ΅ΡΠ΄ΡΠ° (ΠΠΠ‘) Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΡΡΠ°ΡΡΡΠ° ΠΊΡΡΠ΅Π½ΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΎΡΠ΅Π½ΠΊΠ° ΡΠ²ΡΠ·ΠΈ ΠΊΡΡΠ΅Π½ΠΈΡ Ρ Π΄ΡΡΠ³ΠΈΠΌΠΈ ΡΡΠ°Π΄ΠΈΡΠΈΠΎΠ½Π½ΡΠΌΠΈ ΡΠ°ΠΊΡΠΎΡΠ°ΠΌΠΈ ΡΠΈΡΠΊΠ° Ρ ΠΆΠΈΡΠ΅Π»Π΅ΠΉ ΠΡΠ·Π±Π°ΡΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π³ΠΈΠΎΠ½Π° Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 25β64 Π»Π΅Ρ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²Β ΠΌΠ½ΠΎΠ³ΠΎΡΠ΅Π½ΡΡΠΎΠ²ΠΎΠ³ΠΎ ΡΠΏΠΈΠ΄Π΅ΠΌΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Β«ΠΠΏΠΈΠ΄Π΅ΠΌΠΈΠΎΠ»ΠΎΠ³ΠΈΡ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΈΡ
Β ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° Π² Π ΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π€Π΅Π΄Π΅ΡΠ°ΡΠΈΠΈΒ» Π² ΠΠ΅ΠΌΠ΅ΡΠΎΠ²ΡΠΊΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ
Π½Π° ΡΠ»ΡΡΠ°ΠΉΠ½ΠΎΠΉ Π²ΡΠ±ΠΎΡΠΊΠ΅ 1 599 ΡΠ΅Π»ΠΎΠ²Π΅ΠΊ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 25β64 Π»Π΅Ρ. ΠΠΎΠΌΠΈΠΌΠΎ ΡΡΠ°ΡΡΡΠ° ΠΊΡΡΠ΅Π½ΠΈΡ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π»ΠΈΡΡ ΠΏΠΎΠ», Π²ΠΎΠ·ΡΠ°ΡΡ, ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠ΅, Π½Π°Π»ΠΈΡΠΈΠ΅Β ΡΠ°Ρ
Π°ΡΠ½ΠΎΠ³ΠΎ Π΄ΠΈΠ°Π±Π΅ΡΠ° (Π‘Π) ΠΈ Π°ΡΡΠ΅ΡΠΈΠ°Π»ΡΠ½Π°Ρ Π³ΠΈΠΏΠ΅ΡΡΠ΅Π½Π·ΠΈΡ,Β Π³ΠΈΠΏΠ΅ΡΡ
ΠΎΠ»Π΅ΡΡΠ΅ΡΠΈΠ½Π΅ΠΌΠΈΡ, Π³ΠΈΠΏΠ΅ΡΡΡΠΈΠ³Π»ΠΈΡΠ΅ΡΠΈΠ΄Π΅ΠΌΠΈΡ, Π²ΡΡΠΎΠΊΠΈΠΉΒ ΡΡΠΎΠ²Π΅Π½Ρ Π»ΠΈΠΏΠΎΠΏΡΠΎΡΠ΅ΠΈΠ΄ΠΎΠ² Π½ΠΈΠ·ΠΊΠΎΠΉ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΠΈ, Π½ΠΈΠ·ΠΊΠΈΠΉ ΡΡΠΎΠ²Π΅Π½ΡΒ Π»ΠΈΠΏΠΎΠΏΡΠΎΡΠ΅ΠΈΠ΄ΠΎΠ² Π²ΡΡΠΎΠΊΠΎΠΉ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΠΈ (ΠΠΠΠ), Π³ΠΈΠΏΠ΅ΡΠ³Π»ΠΈΠΊΠ΅ΠΌΠΈΡ,Β ΠΎΠΆΠΈΡΠ΅Π½ΠΈΠ΅, Π·Π»ΠΎΡΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΠ΅ Π°Π»ΠΊΠΎΠ³ΠΎΠ»Π΅ΠΌ ΠΈ Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΡ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΡΡΠ°ΡΡΡΠ° ΠΊΡΡΠ΅Π½ΠΈΡΒ ΡΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½Ρ ΡΡΠΈ Π³ΡΡΠΏΠΏΡ. ΠΠ΅ΡΠ²Π°Ρ Π³ΡΡΠΏΠΏΠ° β ΠΊΡΡΡΡΠΈΠ΅ Π²Β Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ, 484 ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° (30,3%), Π²ΡΠΎΡΠ°Ρ β ΠΊΡΡΠΈΠ²ΡΠΈΠ΅ Π²Β ΠΏΡΠΎΡΠ»ΠΎΠΌ, 317 (19,8%), ΠΈ ΡΡΠ΅ΡΡΡ Π³ΡΡΠΏΠΏΠ° β Π½ΠΈΠΊΠΎΠ³Π΄Π° Π½Π΅ ΠΊΡΡΠΈΠ²ΡΠΈΠ΅, 798 ΡΠ΅Π»ΠΎΠ²Π΅ΠΊ (49,9%). ΠΡΡΠΏΠΏΡ Π½Π΅ ΠΈΠΌΠ΅Π»ΠΈ ΡΠ°Π·Π»ΠΈΡΠΈΠΉΒ ΠΏΠΎ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΠΎΡΡΠΈ ΠΠΠ‘. ΠΡΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠΈ ΡΠ°Π½Π³ΠΎΠ²ΠΎΠΉΒ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΠΈ Π²Π»ΠΈΡΠ½ΠΈΡ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° Π½Π° Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΡ ΠΠΠ‘ Π²Β ΠΎΠ±ΡΠ΅ΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ Π²ΡΡΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ Π²ΠΎΠ·ΡΠ°ΡΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ°ΠΌΡΠΌ ΡΠΈΠ»ΡΠ½ΡΠΌ ΡΠ°ΠΊΡΠΎΡΠΎΠΌ, Π° ΠΊΡΡΠ΅Π½ΠΈΠ΅ ΠΈ Π½ΠΈΠ·ΠΊΠΈΠΉ ΡΡΠΎΠ²Π΅Π½Ρ ΠΠΠΠ βΒ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΡΠΌΠΈ. Π‘ΡΠ΅ΠΏΠ΅Π½Ρ Π²Π»ΠΈΡΠ½ΠΈΡ Π½Π° ΠΠΠ‘ ΡΠ°ΠΊΡΠΎΡΠ° ΠΊΡΡΠ΅Π½ΠΈΡ Π²ΡΡΠ΅ Ρ ΠΏΡΠ΅Π΄ΡΡΠ°Π²ΠΈΡΠ΅Π»Π΅ΠΉ ΡΡΠ°ΡΡΠ΅ΠΉ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ, ΠΎΠ΄Π½Π°ΠΊΠΎΠ΄Π°ΠΆΠ΅ Ρ Π»ΠΈΡ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 50 Π»Π΅Ρ ΠΈ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΠΊΡ ΠΊΡΡΠ΅Π½ΠΈΡ Π½Π΅ Π·Π°Π½ΡΠ»Β Π»ΠΈΠ΄ΠΈΡΡΡΡΠΈΠ΅ ΠΏΠΎΠ·ΠΈΡΠΈΠΈ ΠΈ ΡΠ»Π΅Π΄ΠΎΠ²Π°Π» Π·Π° Π‘Π, Π³ΠΈΠΏΠ΅ΡΡΡΠΈΠ³Π»ΠΈΡΠ΅ΡΠΈΠ΄Π΅ΠΌΠΈΠ΅ΠΉ, Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ ΠΈ ΠΎΠΆΠΈΡΠ΅Π½ΠΈΠ΅ΠΌ. ΠΠ΅ΡΠΎΡΡΠ½ΠΎΡΡΡ ΠΠΠ‘ Ρ ΠΊΡΡΡΡΠΈΡ
Π² ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ Ρ Π½ΠΈΠΊΠΎΠ³Π΄Π° Π½Π΅ ΠΊΡΡΠΈΠ²ΡΠΈΠΌΠΈ ΡΡΠΈΠ»ΠΈΠ²Π°Π΅ΡΡΡ ΠΏΡΠΈ ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠΈ ΠΊΡΡΠ΅Π½ΠΈΡ ΡΒ Π³ΠΈΠΏΠ΅ΡΡ
ΠΎΠ»Π΅ΡΡΠ΅ΡΠΈΠ½Π΅ΠΌΠΈΠ΅ΠΉ, Π³ΠΈΠΏΠ΅ΡΡΡΠΈΠ³Π»ΠΈΡΠ΅ΡΠΈΠ΄Π΅ΠΌΠΈΠ΅ΠΉ, ΠΌΡΠΆΡΠΊΠΈΠΌ ΠΏΠΎΠ»ΠΎΠΌ, ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ΠΌ Π²ΡΡΡΠ΅Π³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, Π½Π°Π»ΠΈΡΠΈΠ΅ΠΌΒ Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΠΈ ΠΈ Π²ΠΎΠ·ΡΠ°ΡΡΠΎΠΌ 50 Π»Π΅Ρ ΠΈ ΡΡΠ°ΡΡΠ΅. Π£ ΠΊΡΡΠΈΠ²ΡΠΈΡ
Π² ΠΏΡΠΎΡΠ»ΠΎΠΌ ΠΊ Π½Π΅ ΠΊΡΡΡΡΠΈΠΌ β ΠΏΡΠΈ ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠΈ Ρ Π³ΠΈΠΏΠ΅ΡΠ³Π»ΠΈΠΊΠ΅ΠΌΠΈΠ΅ΠΉ.Β ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΡΡΠ΅Π½ΠΈΠ΅ ΡΠ²Π»ΡΠ΅ΡΡΡ Π½Π΅ ΠΏΠ΅ΡΠ²ΠΎΡΡΠ΅ΠΏΠ΅Π½Π½ΡΠΌΒ ΡΠ°ΠΊΡΠΎΡΠΎΠΌ ΡΠΈΡΠΊΠ° ΠΏΡΠΈ Π²ΡΡΠ²Π»Π΅Π½ΠΈΠΈ ΠΠΠ‘ Π² ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΠΎΠΉ Π²ΡΠ±ΠΎΡΠΊΠ΅, Π° ΠΏΡΠΈ Π½Π°Π»ΠΈΡΠΈΠΈ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ°Β Π²Π»ΠΈΡΠ½ΠΈΠ΅ ΠΊΡΡΠ΅Π½ΠΈΡ Π½Π° Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΡ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΠΠΠ‘ ΡΡΠΈΠ»ΠΈΠ²Π°Π΅ΡΡΡ.
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