Przestrzenna zmienność morfologii plaży pod kątem grzbietów i strumieni spowodowana powstaniem kopalni złóż okruchowych wzdłuż Vembar – Wybrzeże Kallar w Indiach

This article does not contain abstracts in English.Celem tej pracy jest omówienie przestrzennych i krótkotrwałych zmian w morfologii plaży pod kątem grzbietów i strumieni na podstawie profili plaży w Vembar, na wybrzeżu Kallar, Tamil Nadu, Indie. Plaże składają się głównie z średniego do grubego piasku i ciężkich minerałów. Dla plaż charakterystyczne są grzbiety, strumienie i zagłębienia. Grzbiety i strumienie są niewielkie ze względu na prace kopalniane prowadzone w okolicy. Ustalono, że przestrzenne i tymczasowe zmiany w systemie grzbietów i strumieni są kontrolowane przez pianę morską/łamiące się fale. Zmiany objętości sedymentu wynikają z nieregulowanej aktywności kopalni. Erozja ma wpływ na profil wszystkich plaż, zwłaszcza strumieni. Strefy przyrostu znajdują się wyżej, to znaczy na najwyższych grzbietach i wałach plażowych. Krótkotrwałe zmiany wielkości plaży wyjaśniają zniekształcenie grzbietów i strumieni. Ma to związek z pobliską kopalnią. Zaobserwowano wzorzec wiatru wyżej plaży, gdzie warunki pozwalają na transport sedymentu piasku i jego ruch na grzbietach i strumieniach

Synthesis And Characterization Of Undoped And Co-Doped SnO2 Nanoparticles

Undoped and Co-doped (1 and 3 at. %) SnO2 nanoparticles were synthesized by a simple co-precipitation method. X-Ray diffraction data revealed that both undoped and doped samples crystallize in the tetragonal rutile phase with CoO phase in doped samples. The lattice parameters of doped samples calculated from XRD data do not vary much when compared to undoped one indicating that Co has not substituted the host lattice. The surface morphology investigated by SEM indicates the cluster formation in Co-doped (1 and 3 at. %) nanoparticles and the chemical composition of the samples were analyzed by energy dispersive spectroscopy (EDS). UV-Vis spectrum of undoped system showed absorption at 408 nm (3.04 eV), which is red shifted by 0.56 eV compared to bulk SnO2 (3.6 eV) due to the cluster nature of the sample. The UV-Vis spectra of doped samples showed absorption in the visible region due to the formation of CoO phase, which is also evident from the XRD spectra. PL spectra showed characteristic UV emission at 409 nm and blue emission at 480 nm. The characteristic vibrational modes of SnO2 were studied from FTIR analysis. EPR measurement of Co-doped (3 at .%) SnO2 nanoparticles showed the paramagnetic behavior which may be attributed to the occupation of Co2+ ions in the interstitial site rather than the substitutional site. The absence of ferromagnetism is due to the high doping concentration of Co (> 1 at. %) and also due to the high annealing temperature which destroys the hyperfine splitting. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/939

In Vitro Screening of Cytotoxic, Antimicrobial and Antioxidant Activities of Clinacanthus nutans (Acanthaceae) leaf extracts

Purpose: To evaluate the in vitro cytotoxic, antioxidant and antimicrobial activities of Clinacanthus nutans extracts and semi-fractions.Method: The plant was subjected to cold solvent extraction to produce petroleum ether, ethyl acetate and methanol crude extracts, followed by isolation using bioassay-guided fractionation. The crude extracts (0.2 to 10.0 mg/ml) were tested against HeLa and K-562 cell lines using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and antioxidant activity using 1, 1-diphenyl-2- picrylhydrazyl (DPPH) assay. Furthermore, fractions isolated from ethyl acetate leaf extract (0.02 to10.0 mg/ml) were tested against Bacillus cereus (ATCC11778), Escherichia coli (ATCC25922), Salmonella enterica Typhimurium (ATCC14028) and Candida albicans (ATCC10231) using minimum inhibitory concentration (MIC) and minimum bactericidal or fungicidal (MBC/MFC) assays.Results: Petroleum ether extracts demonstrated the strongest cytotoxic activity against HeLa and K-562 cells with IC50 of 18.0 and 20.0 ìg/mL, respectively. Petroleum ether extracts also displayed the highest radical scavenging activity of 82.00 ± 0.02 %, compared with ascorbic acid and á-tocopherol corresponding values of 88.7 ± 0.0 and 86.6 ± 0.0 %, respectively. In MIC assay, all the crude extracts and fractions showed inhibition against all tested microorganisms. Fraction 7 displayed the lowest MIC and MBC/MFC values against B. cereus and C. albicans at 1.39 mg/ml, respectively. Ampicillin and amphotericin B displayed MIC value of 1.3 mg/ml.Conclusion: The bioactive compounds from C. nutans are potential  cytotoxic, antimicrobial and antioxidant agents.Keywords: Clinacanthus nutans, Cytotoxic, Antioxidant, Antimicrobia

Identification of Beryllium Hydride Isotopomer Lines in Sunspot Umbral Spectra

A high resolution spectrum of FTS sunspot umbra of NSO/Kitt Peak was used to conduct a search for the molecular absorption lines due to BeH, BeD and BeT isotopomers. Analysis led to estimates of identification of the molecular lines of bands A - X (0,0), (1,1) and (2,2) for BeH, A - X (0,0), (1,1), (2,2) and (3,3) for BeD and of A - X (0,0), (1,1) and (2,2) for BeT. Among the identified lines, those which are well resolved were selected for measurements to calculate equivalent widths. The values of effective rotational temperature T were estimated for bands A - X(1,1) and (2,2) of BeH, A - X(1,1) of BeD and A - X(2,2) of BeT to be 4228K, 4057K, 3941K and 3243K respectively

Simulation of a dipeptide Boc-Ile-Ile-NHMe as a drug carrier

Reverse micelles are discrete nanoscale particles composed of a water core surrounded by surfactant. In this current study the the self assembling properties of the dipeptide Boc-Ile-Ile-NHMe in chloroform to form a stable micelle at various temperatures ranging from 200 to 350 Kelvin has been analysed using insilico methods. The computational analysis was carried out using the steepest descent algorithm, a minimization tool used to study the protein energy level in insilco and it was compared with the thermodynamic parameters determined experimentally. Such reverse micelles finds a vast area of application one of which is drug delivery in nanotechnology. The present dipeptide is shown to carry drugs by insilico methods.   Key words: Reverse micelles, tetra peptide, minimization, drug delivery, nanotechnology

Expression of proto-oncogenes and muscle specific genes during cardiac hypertrophy and development in rats and humans

A regulatory interdependence of expression of proto-oncogenes and muscle specific genes observed in smooth muscle was examined in cardiac muscle during normal development and hypertrophy both in rats and humans. During normal development in rats, myosin light chain 2 expression is very low at prenatal stages, while c-fos expression starts from the early stages of embryonic development. In aorta constricted rats c-fos induction occurs within 30 min whereas myosin light chain 2 expression is sufficiently high only after 3 or 4 days of post operative period. In the case of humans, the expression of myosin light chain 2 as well as c-fos occurs at high levels during embryonic development. Similar results were obtained with tissue samples obtained from patients with cardiac abnormalities. Induction of the c-fos gene in cultured myocytes by 12-O-tetradeeanoylphorbol 13-acetate has no influence on the expression of myosin light chain 2. These studies were extended with studies on c-myc and Β-myosin heavy chain gene expression which revealed a similar pattern of expression as that of c-fos and myosin light chain 2. These results have indicated that the expression of proto-oncogenes in cardiac muscle may be independently regulated from the expression of muscle specific genes

Case report of total hip replacement in an amputatee

Total hip replacement (THR) in an ipsilateral neck of femur fracture is an unusual situation. Hip fractures are a common source of morbidity and mortality worldwide. Nevertheless, the discovery and development of hip arthroplasty has improved its prognosis, with a high survival rate and satisfactory functional results. Although total hip replacement has been well described in the literature especially for healthy individuals, we found only few pieces of information about the technical characteristics and results of this procedure in patients with lower extremity amputation. There were few previous case reports in the literature that describe total hip replacement (THR) in above-knee amputees and this was the first case to be done in our institute. We presented a case involving an above knee amputee (AKA) who sustained an ipsilateral neck of femur fracture. Our patient underwent a THR with a satisfactory post-operative outcome. Technical considerations for AKAs undergoing THR also are reviewed in this article

Cytotoxic Effect and Antioxidant Activity of Bioassay-guided Fractions from Solanum nigrum Extracts

Purpose: To evaluate the cytotoxic effect and antioxidant activity of bioassay-guided fractions from Malaysian species of Solanum nigrum.Methods: Methanol leaf and ethanol fruit extracts of Solanum nigrum were subjected to bioassay-guided fractionation using column chromatography. The semi-purified fractions were investigated for their in vitro cytotoxic effect against various cancer cell lines using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium bromide (MTT) assay, and for antioxidant activity using 2, 2-diphenyl-1- picryhydrazyl (DPPH) assay.Results: From bioassay-guided fractionation, 13 and 17 fractions were obtained from the methanol leaf and ethanol fruit extracts, respectively. In MTT assay, fractions 1, 2 and 4 from methanol extract showed the highest cytotoxic effect against the cancer cells with IC50 of 13.0 μg/mL at 48 h incubation. For the ethanol extract, fractions 14 and 15 showed the highest cytotoxic effect with IC50 of 12.0 μg/mL against K-562 cells, while fractions 13, 14 and 17 showed IC50 of 13.0 μg/mL against HeLa cells. Doxorubicin hydrochloride and vinblastine sulfate inhibited the cancer cells with IC50 range of 1.3 to 17.0 μg/mL. The highest radical scavenging activity was exhibited by fraction 2 from methanol extract with ED50 value of 0.10 mg/ml, while fraction 15 from ethanol extract showed ED50 of 0.79 mg/mL. Ascorbic acid and α-tocopherol exhibited radical scavenging activity of 95.0 ± 0.01 % (ED50 = 0.05 mg/mL) and 93.0 ± 0.01 % (ED50 = 0.10 mg/mL), respectively.Conclusion: Solanum nigrum leaves and fruits are potential sources of cytotoxic and antioxidant agents.Keywords: Solanum nigrum, Cytotoxic Activity, Anti-oxidant Activity, Bioassay-guided Fractionation, Doxorubicin, Vinblastin

Simulation of a dipeptide Boc-Ile-Ile-NHMe as a drug carrier

Reverse micelles are discrete nanoscale particles composed of a water core surrounded by surfactant. In this current study the the self assembling properties of the dipeptide Boc-Ile-Ile-NHMe in chloroform to form a stable micelle at various temperatures ranging from 200 to 350 Kelvin has been analysed using insilico methods. The computational analysis was carried out using the steepest descent algorithm, a minimization tool used to study the protein energy level in insilco and it was compared with the thermodynamic parameters determined experimentally. Such reverse micelles finds a vast area of application one of which is drug delivery in nanotechnology. The present dipeptide is shown to carry drugs by insilico methods.   Key words: Reverse micelles, tetra peptide, minimization, drug delivery, nanotechnology

Astrophysical molecule CN : vibronic transition probability parameters

Abstract. Astrophysical applications are broadened by the emerging consensus on the vibration-electronic (vibronic) transition probability parameters such as Franck -Condon (FC) factors & r -centroids of some molecular species like CN , which could be useful in the identification of molecular lines and in the estimation of relative abundance of the species in various celestial bodies especially in the interstellar medium. Such important parameters, that is FC factors and r -centroids, have been computed by a reliable numerical integration procedure for the bands of E i systems of astrophysical molecule CN , using a suitable potential. For E − X system, the improved values of FC factors from the revised molecular constants are given along with the already reported values