22,281 research outputs found
Numerical solutions of Navier-Stokes equations for compressible turbulent two/three dimensional flows in terminal shock region of an inlet/diffuser
The multidimensional ensemble averaged compressible time dependent Navier Stokes equations in conjunction with mixing length turbulence model and shock capturing technique were used to study the terminal shock type of flows in various flight regimes occurring in a diffuser/inlet model. The numerical scheme for solving the governing equations is based on a linearized block implicit approach and the following high Reynolds number calculations were carried out: (1) 2 D, steady, subsonic; (2) 2 D, steady, transonic with normal shock; (3) 2 D, steady, supersonic with terminal shock; (4) 2 D, transient process of shock development and (5) 3 D, steady, transonic with normal shock. The numerical results obtained for the 2 D and 3 D transonic shocked flows were compared with corresponding experimental data; the calculated wall static pressure distributions agree well with the measured data
Patterns of Employee Particpation and Industrial Democracy in UK ESOPs
This paper examines the institutional characteristics of UK ESOPs and considers the extent to which ESOPs extend employee participation and industrial democracy. It is suggested that ESOPs in themselves do not extend industrial democracy. Instead patterns of employee participation are substantially determined by the goals of those primarily responsible for establishing the ESOP. Three constellations of ESOPs are discerned on the basis of their participative characteristics: `technical ESOPs' where there is little or no development of industrial democracy; `paternalist ESOPs' which tend to develop individualistic forms of employee participation; and `representative ESOPs' where new institutions are created to give some opportunity for involvement of employee representatives in top decisions.
Electrical and infrared properties of thin niobium microbolometers near T(sub c)
Niobium microbolometers approximately 1 micron wide x 2 micron long x 10 nm thick have been integrated at the feeds of equiangular spiral antennas made of 200 nm thick Nb. The device's current-voltage characteristics and infrared responsivity as a function of DC bias voltage were measured over a range of temperature spanning approximately plus or minus 2 percent around T(sub c). The greatest voltage responsivity occurs well below T(sub c), in a regime where the I-V curve is significantly hysteretic due to self-heating and resembles the I-V curve of a superconducting microbridge
The effect of eccentric and concentric training on the size and strength of human skeletal muscle
The objective of this study was to determine if the high forces generated through eccentric contractions, and the subsequent damage sustained, contributes to greater growth and force increase in human skeletal muscle than other contraction types, and whether damage from eccentric exercise effects the increase in torque and muscle size expected after a progressive concentric strength training program. 20 healthy subjects were split into four groups which participated in 3 different training protocols, with one group serving as the control (C). Groups underwent either concentric training (CT), eccentric damage (ED), or a combination of the two protocols (DC) with the non-preferred biceps over a twelve week period. Isometric and concentric force at 50, 90 and 200°/sec was measured weekly with a Cybex isokinetic dynamometer. Upper arm girth was also measured pre and post training. The CT group displayed the greatest increase in peak torque for both isometric and concentric contractions. The groups undergoing eccentric damage (ED & DC) showed a decrease in the ability to generate force in the weeks following damage, and showed only small torque increases over the twelve weeks with DC improving to a greater extent than ED at higher contraction velocities. Eccentric damage appeared to attenuate the increases in peak torque displayed after concentric training. A hypertrophic response from damage may have resulted in a decrease in muscle strength per unit cross-sectional area, and the failure of DC to respond to training may be due to the inability to generate sufficient intramuscular tension required to elicit an adaptive response
How to measure redshift-space distortions without sample variance
We show how to use multiple tracers of large-scale density with different
biases to measure the redshift-space distortion parameter
beta=f/b=(dlnD/dlna)/b (where D is the growth rate and a the expansion factor),
to a much better precision than one could achieve with a single tracer, to an
arbitrary precision in the low noise limit. In combination with the power
spectrum of the tracers this allows a much more precise measurement of the
bias-free velocity divergence power spectrum, f^2 P_m - in fact, in the low
noise limit f^2 P_m can be measured as well as would be possible if velocity
divergence was observed directly, with rms improvement factor ~[5.2(beta^2+2
beta+2)/beta^2]^0.5 (e.g., ~10 times better than a single tracer for beta=0.4).
This would allow a high precision determination of f D as a function of
redshift with an error as low as 0.1%. We find up to two orders of magnitude
improvement in Figure of Merit for the Dark Energy equation of state relative
to Stage II, a factor of several better than other proposed Stage IV Dark
Energy surveys. The ratio b_2/b_1 will be determined with an even greater
precision than beta, producing, when measured as a function of scale, an
exquisitely sensitive probe of the onset of non-linear bias. We also extend in
more detail previous work on the use of the same technique to measure
non-Gaussianity. Currently planned redshift surveys are typically designed with
signal to noise of unity on scales of interest, and are not optimized for this
technique. Our results suggest that this strategy may need to be revisited as
there are large gains to be achieved from surveys with higher number densities
of galaxies.Comment: 22 pages, 13 figure
Mining whole sample mass spectrometry proteomics data for biomarkers: an overview
In this paper we aim to provide a concise overview of designing and conducting an MS proteomics experiment in such a way as to allow statistical analysis that may lead to the discovery of novel biomarkers. We provide a summary of the various stages that make up such an experiment, highlighting the need for experimental goals to be decided upon in advance. We discuss issues in experimental design at the sample collection stage, and good practise for standardising protocols within the proteomics laboratory. We then describe approaches to the data mining stage of the experiment, including the processing steps that transform a raw mass spectrum into a useable form. We propose a permutation-based procedure for determining the significance of reported error rates. Finally, because of its general advantages in speed and cost, we suggest that MS proteomics may be a good candidate for an early primary screening approach to disease diagnosis, identifying areas of risk and making referrals for more specific tests without necessarily making a diagnosis in its own right. Our discussion is illustrated with examples drawn from experiments on bovine blood serum conducted in the Centre for Proteomic Research (CPR) at Southampton University
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