56 research outputs found
Testing the Environmental Kuznets Curve hypothesis on land use: The case of Romania
The aim of the present study is to test empirically the Environmental Kuznets Curve (EKC) hypothesis for 42 Romanian counties over the 2000-2014 period. Specifically, we investigate the existence of an inverted U-shaped curve relationship between residential built-up land and economic development in a low-income EU country undergoing rapid and profound transition. We do so by making innovative use of spatial panel econometric techniques. Contrary to our expectations, the results indicate an inverted EKC, implying that higher levels of residential built-up area occur for higher levels of wealth. Moreover, we find that the built-up land in Romania mainly reflects processes of urban expansion, such as sprawl or suburbanization, that may have harmful environmental and social consequences. Spatial spill-overs in terms of built-up land arise and spread, albeit to a limited extent, to neighbouring locations. These findings are of potential significance for policy makers, because they highlight the need for coordination among neighbours. Furthermore, strengthening the institutional framework and local tax management, and planning urban regeneration better could curb and even reverse the extensive built-up land expansion and real estate speculation
The chemical etching as a method for post-processing of 3D cellular structures obtained by electron-beam melting: limitations and difficulties
Chemical etching is a promising method for post-surface treatment and the removal of residual powder from implants obtained using electron beam cladding. Partially sintered powder particles that remained on the implants surface can be difficult to remove from the internal structure of the additively manufactured specimens. In order to remove residual powder from scaffolds' interior, an aqueous solution of HF and HNO3 acids was used. Multiple immersion was more effective to remove the remaining powder, which was explained from the chemical point of view. The influence of the chemical etching on mechanical properties, mechanical behavior, fracture modes, and morphology was investigated
SUFU haploinsufficiency causes a recognisable neurodevelopmental phenotype at the mild end of the Joubert syndrome spectrum.
Joubert syndrome (JS) is a recessively inherited ciliopathy characterised by congenital ocular motor apraxia (COMA), developmental delay (DD), intellectual disability, ataxia, multiorgan involvement, and a unique cerebellar and brainstem malformation. Over 40 JS-associated genes are known with a diagnostic yield of 60%-75%.In 2018, we reported homozygous hypomorphic missense variants of the SUFU gene in two families with mild JS. Recently, heterozygous truncating SUFU variants were identified in families with dominantly inherited COMA, occasionally associated with mild DD and subtle cerebellar anomalies.
We reanalysed next generation sequencing (NGS) data in two cohorts comprising 1097 probands referred for genetic testing of JS genes.
Heterozygous truncating and splice-site SUFU variants were detected in 22 patients from 17 families (1.5%) with strong male prevalence (86%), and in 8 asymptomatic parents. Patients presented with COMA, hypotonia, ataxia and mild DD, and only a third manifested intellectual disability of variable severity. Brain MRI showed consistent findings characterised by vermis hypoplasia, superior cerebellar dysplasia and subtle-to-mild abnormalities of the superior cerebellar peduncles. The same pattern was observed in two out of three tested asymptomatic parents.
Heterozygous truncating or splice-site SUFU variants cause a novel neurodevelopmental syndrome encompassing COMA and mild JS, which likely represent overlapping entities. Variants can arise de novo or be inherited from a healthy parent, representing the first cause of JS with dominant inheritance and reduced penetrance. Awareness of this condition will increase the diagnostic yield of JS genetic testing, and allow appropriate counselling about prognosis, medical monitoring and recurrence risk
the effects of climate change on the multifunctional role of basilicata s forests the effects induced on yield and co2 absorption
The first studies on the possible impact of climate change on European forests and the development of adaptation and mitigation strategies began in the 1990s and resulted in the identification of risk assessment models and forest management tools. The prediction of climate change impacts on forests has been based using the evidence theory or Dempster-Shafer (DS)'s theory, appropriately spatialised. The implemented evidence lines refer to the concepts of vulnerability and resilience. The results of the DS model, applied to the Basilicata region, were utilised to assess the loss in biomass production capacity and CO2 absorption ability of different forest-derived biomasses. The loss in stumpage value and in the estimated CO2 absorption shows a reduction over time of forest system's economic value that is basically higher in 2050 than in 2100. The applied methodological approach has shown that the high degree of spatial and information detail may be helpful to produce good predictions to envisage environmental policy strategies for the monitoring and mitigation of the damages caused by the climate change, with a view to ensuring the ecosystems' capacity to produce positive externalities, including air carbon sequestration capacity
Challenges and Opportunities to Regional Renewal in the European Union
The strength of the 2008 financial and economic crisis and the resulting degree of resilience were heterogeneous among and within the European Union countries. Challenges and opportunities driven by regional-specific differences determined the ability to overshoot the precrisis levels of growth. Focusing upon Nomenclature of Territorial Units for Statistics 2 (NUTS 2) European regions, we explore a novel conceptual framework related to regional economic resilience, namely the renewal capacity. Precisely, we concentrate on the capacity of regional economies to “renew” their growth paths in the labor market in the aftermath of the recent global crisis. We find some well-identified spatial patterns of regional employment renewal and we identify a set of territorial assets that allow regions to bounce back faster and more comprehensively than others to the economic downturn. Furthermore, there are significant differences between the drivers of the regional renewal of Old and New Member States. Our findings suggest potential policy directions at all levels for enhancing regional resilience
A composite policy tool to measure territorial resilience capacity
The 2007–2008 global recession and consequent slow recovery have revealed considerable heterogeneity in economic performance across countries and regions. This study contributes innovatively to existing resilience literature by identifying a life cycle resilience framework and computing a “handy” composite Regional Economic Resilience Indicator. We analyse economic resilience by means of a cluster and exploratory spatial data analysis, revealing well-defined spatial patterns in the EU. National resilience trends dominate in the EU-15, while a more heterogeneous spatial pattern is present in the EU-13. Our findings can support the monitoring of economic resilience at regional level and facilitate a common understanding of this complex and dynamic process for policy purposes
A composite policy tool to measure territorial resilience capacity
The 2007–2008 global recession and consequent slow recovery have revealed considerable heterogeneity in economic performance across countries and regions. This study contributes innovatively to existing resilience literature by identifying a life cycle resilience framework and computing a “handy” composite Regional Economic Resilience Indicator. We analyse economic resilience by means of a cluster and exploratory spatial data analysis, revealing well-defined spatial patterns in the EU. National resilience trends dominate in the EU-15, while a more heterogeneous spatial pattern is present in the EU-13. Our findings can support the monitoring of economic resilience at regional level and facilitate a common understanding of this complex and dynamic process for policy purposes
Validation of a serial-parallel model in the numerical simulation of the mechanical response of fiber-reinforced composite materials
Validation of a serial-parallel model in the numerical simulation of the mechanical response of fiber-reinforced composite materials
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