656 research outputs found
Critical Cooperation Range to Improve Spatial Network Robustness
A robust worldwide air-transportation network (WAN) is one that minimizes the
number of stranded passengers under a sequence of airport closures. Building on
top of this realistic example, here we address how spatial network robustness
can profit from cooperation between local actors. We swap a series of links
within a certain distance, a cooperation range, while following typical
constraints of spatially embedded networks. We find that the network robustness
is only improved above a critical cooperation range. Such improvement can be
described in the framework of a continuum transition, where the critical
exponents depend on the spatial correlation of connected nodes. For the WAN we
show that, except for Australia, all continental networks fall into the same
universality class. Practical implications of this result are also discussed
Post-operative morbidity following pancreatic duct occlusion without anastomosis after pancreaticoduodenectomy: a systematic review and meta-analysis
Background: Pancreatic duct occlusion (PDO) without anastomosis is a technique proposed to mitigate the clinical consequences of postoperative pancreatic fistulas (POPF) after pancreaticoduodenectomy. The aim of this study was to appraise the morbidity following PDO through a systematic review and meta-analysis. Methods: A systematic search of MEDLINE, Embase, and Web Of Science identified studies reporting outcomes of PDO following pancreaticoduodenectomy. Pooled prevalence rates of postoperative complications and mortality were computed using random-effect modeling. Meta-regression analyses were performed to examine the impact of moderators on the overall estimates. Results: Sixteen studies involving 1000 patients were included. Pooled postoperative mortality was 2.7%. A POPF was reported in 29.7% of the patients. Clinically relevant POPFs occurred in 13.5% of the patients, while intra-abdominal abscess and haemorrhages occurred in 6.7% and 5.5% of the patients, respectively. Re-operation was necessary in 7.6% of the patients. Postoperatively new onset diabetes occurred in 15.8% of patients, more frequently after the use of chemical substances for PDO (p = 0.003). Conclusions: PDO is associated with significant morbidity including new onset of post-operative diabetes. The risk of new onset post-operative diabetes is associated with the use of chemical substance for PDO. Further evidence is needed to evaluate the potential benefits of PDO in patients at high risk of POPF
Hawks and Doves on Small-World Networks
We explore the Hawk-Dove game on networks with topologies ranging from
regular lattices to random graphs with small-world networks in between. This is
done by means of computer simulations using several update rules for the
population evolutionary dynamics. We find the overall result that cooperation
is sometimes inhibited and sometimes enhanced in those network structures, with
respect to the mixing population case. The differences are due to different
update rules and depend on the gain-to-cost ratio. We analyse and qualitatively
explain this behavior by using local topological arguments.Comment: 12 pages, 8 figure
Worldwide spreading of economic crisis
We model the spreading of a crisis by constructing a global economic network
and applying the Susceptible-Infected-Recovered (SIR) epidemic model with a
variable probability of infection. The probability of infection depends on the
strength of economic relations between the pair of countries, and the strength
of the target country. It is expected that a crisis which originates in a large
country, such as the USA, has the potential to spread globally, like the recent
crisis. Surprisingly we show that also countries with much lower GDP, such as
Belgium, are able to initiate a global crisis. Using the {\it k}-shell
decomposition method to quantify the spreading power (of a node), we obtain a
measure of ``centrality'' as a spreader of each country in the economic
network. We thus rank the different countries according to the shell they
belong to, and find the 12 most central countries. These countries are the most
likely to spread a crisis globally. Of these 12 only six are large economies,
while the other six are medium/small ones, a result that could not have been
otherwise anticipated. Furthermore, we use our model to predict the crisis
spreading potential of countries belonging to different shells according to the
crisis magnitude.Comment: 13 pages, 4 figures and Supplementary Materia
Minimal length in quantum space and integrations of the line element in Noncommutative Geometry
We question the emergence of a minimal length in quantum spacetime, comparing
two notions that appeared at various points in the literature: on the one side,
the quantum length as the spectrum of an operator L in the Doplicher
Fredenhagen Roberts (DFR) quantum spacetime, as well as in the canonical
noncommutative spacetime; on the other side, Connes' spectral distance in
noncommutative geometry. Although on the Euclidean space the two notions merge
into the one of geodesic distance, they yield distinct results in the
noncommutative framework. In particular on the Moyal plane, the quantum length
is bounded above from zero while the spectral distance can take any real
positive value, including infinity. We show how to solve this discrepancy by
doubling the spectral triple. This leads us to introduce a modified quantum
length d'_L, which coincides exactly with the spectral distance d_D on the set
of states of optimal localization. On the set of eigenstates of the quantum
harmonic oscillator - together with their translations - d'_L and d_D coincide
asymptotically, both in the high energy and large translation limits. At small
energy, we interpret the discrepancy between d'_L and d_D as two distinct ways
of integrating the line element on a quantum space. This leads us to propose an
equation for a geodesic on the Moyal plane.Comment: 29 pages, 2 figures. Minor corrections to match the published versio
Mechanisms of network changes in cognitive impairment in multiple sclerosis
Background and objectives: Cognitive impairment in multiple sclerosis (MS) is associated with functional connectivity abnormalities. While there have been calls to use functional connectivity measures as biomarkers, there remains to be a full understanding of why they are affected in MS. In this cross-sectional study, we tested the hypothesis that functional network regions may be susceptible to disease-related "wear and tear" and that this can be observable on co-occurring abnormalities on other magnetic resonance metrics. We tested whether functional connectivity abnormalities in cognitively impaired patients with MS co-occur with (1) overlapping, (2) local, or (3) distal changes in anatomic connectivity and cerebral blood flow abnormalities. Methods: Multimodal 3T MRI and assessment with the Brief Repeatable Battery of Neuropsychological tests were performed in 102 patients with relapsing-remitting MS and 27 healthy controls. Patients with MS were classified as cognitively impaired if they scored ≥1.5 SDs below the control mean on ≥2 tests (n = 55) or as cognitively preserved (n = 47). Functional connectivity was assessed with Independent Component Analysis and dual regression of resting-state fMRI images. Cerebral blood flow maps were estimated, and anatomic connectivity was assessed with anatomic connectivity mapping and fractional anisotropy of diffusion-weighted MRI. Changes in cerebral blood flow and anatomic connectivity were assessed within resting-state networks that showed functional connectivity abnormalities in cognitively impaired patients with MS. Results: Functional connectivity was significantly decreased in the anterior and posterior default mode networks and significantly increased in the right and left frontoparietal networks in cognitively impaired relative to cognitively preserved patients with MS (threshold-free cluster enhancement corrected at p ≤ 0.05, 2 sided). Networks showing functional abnormalities showed altered cerebral blood flow and anatomic connectivity locally and distally but not in overlapping locations. Discussion: We provide the first evidence that functional connectivity abnormalities are accompanied by local cerebral blood flow and structural connectivity abnormalities but also demonstrate that these effects do not occur in exactly the same location. Our findings suggest a possibly shared pathologic mechanism for altered functional connectivity in brain networks in MS
Learning and innovative elements of strategy adoption rules expand cooperative network topologies
Cooperation plays a key role in the evolution of complex systems. However,
the level of cooperation extensively varies with the topology of agent networks
in the widely used models of repeated games. Here we show that cooperation
remains rather stable by applying the reinforcement learning strategy adoption
rule, Q-learning on a variety of random, regular, small-word, scale-free and
modular network models in repeated, multi-agent Prisoners Dilemma and Hawk-Dove
games. Furthermore, we found that using the above model systems other long-term
learning strategy adoption rules also promote cooperation, while introducing a
low level of noise (as a model of innovation) to the strategy adoption rules
makes the level of cooperation less dependent on the actual network topology.
Our results demonstrate that long-term learning and random elements in the
strategy adoption rules, when acting together, extend the range of network
topologies enabling the development of cooperation at a wider range of costs
and temptations. These results suggest that a balanced duo of learning and
innovation may help to preserve cooperation during the re-organization of
real-world networks, and may play a prominent role in the evolution of
self-organizing, complex systems.Comment: 14 pages, 3 Figures + a Supplementary Material with 25 pages, 3
Tables, 12 Figures and 116 reference
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