PAPILOMAVIRUS INFECTION IN WOMEN WITH HIV

We developed diagnostic protocol and studied cervical diseases in 733 women with HIV. There were found high incidence of sexual transmitted diseases and multifocal papilloma in these patients. We describe colposcopical signs of cervical papilloma virus infection in HIV-positive women. We suppose that low information content of cervical cytology could be connected with concomitant infections. We also found that HIV is not eliminated but cause to dysplasia of cervical epithelium. That is why we suppose to optimal to pay an attention to cervical neoplasms in women with HIV-PVI association. Severity of observed cervical changes was depended on the associations with sexual transmitted infections, CD4+ lymphocytes level and total virus load

Distribution of dirofilariasis in Omsk region

Background. Recently, in the Russian Federation, there has been a tendency to an increase in the number of registered cases of dirofilariasis among residents living in a temperate climate zone, including in Western Siberia. The species Dirofilaria repens and Dirofilaria immitis are of clinical importance for humans. Dirofilariae are characterized by migration into the subcutaneous tissue, mucous membranes, organs of vision, internal organs. In the Omsk region, there is an increase in cases of dirofilariasis, including among children.The aim. To assess endemicity of the territory of the Omsk region in relation to pathogens of dirofilariasis.Materials and methods. The maps of the epidemiological survey of persons infected with dirofilariae for the period 2013–2020 were analyzed, parasitological and molecular biological methods examined 1155 blood samples of dogs, 2488 samples female blood-sucking mosquitoes, 26 samples of dirofilaria helminths removed from residents of the Omsk region.Results. In 18 people, the infection was regarded as local, since the infected persons had not left the Omsk region for the previous three years. Local infections are reported annually. Infection of the final owners – dogs – with dirofilaria ranges from 0.6 to 4.8 % in different years. On average, the extensiveness of the invasion was 3.0 ± 0.6 %; and the intensity of microfilaremia was 1277.68 ± 395.87 specimens/ml of blood. On the territory of Omsk and the Omsk region, 11 species of mosquitoes belonging to the genus Aedes, Ochlerotatus, Culex, Anopheles, Coquillettidia were identified. The estimated individual infection of mosquitoes of different species ranged from 0.6 % (O. flavescens) to 9.8 % (An. messeae). The total infection of vectors was 3.4 %. All positive samples were found to contain DNA of D. repens.Conclusion. The territory of the Omsk region is endemic for pathogens of dirofilariasis, in particular, D. repens. Further studies are needed to study the prevalence and species diversity of pathogens of dirofilariasis in Western Siberia, to identify the most dangerous from an epidemiological point of view, species of vectors

Therapeutic physical training for arthrosis of the shoulder joints of athletes

This article examines the statistics of the occurrence of arthrosis of the shoulder joints in athletes and its connection with the popularization of various sports, as well as compares the methods of treatment of this diseaseВ данной статье рассматривается статистика возникновения артроза плечевых суставов у спортсменов и связь её с популяризацией различных видов спорта, а также сравниваются методы лечения данного заболевания. Артроз часто является следствием травмы, поэтому в статье будет рассмотрена статистика травм плечевого сустав

Business Writing: Linguistic Approach Through The Prism Of Speech Activity Theory

The format of business writing has significantly changed for the reason that each genre of written business discourse has its own strictly codified form. Expansion of communication fields including business communication domain affects the form of business discourse realization. In this regard, to justify the hypothesis of changing previously established speech forms functioning as a business letter genre, the present paper focuses on identification and systemizing characteristics of written documents, such as structural, lexical and stylistic markers of national and cultural specificity of English written communication. In accordance with the principles of speech activity theory and communication theory the article presents the stages of development of business contact and analyzes the structure of business writing. In the article, the structure of the business letter is presented in compliance with the intent of the addressee. The authors propose several types of exercises aimed to enhance understanding of correlation between the addressor’s intention and lexical means, as well as rubrication principles. A list of criteria for evaluating the effectiveness of written communications is also demonstrated.Theoretical interpretation of written modus of business communication based on speech activity theory and communication theory is instrumental for the analysis of constituents of written business communication act through the prism of the addressor’s communicative intentions. The approach proposed may be used in teaching practical course of the English language with the view to form universal competences of future linguists, as well as in the study of business written communication for further theoretical interpretation

Genetic engineering of peptide hormones

Peptide and polypeptide hormones represent an extensive group of biologically active compounds of important significance for medicine and agriculture. In recent years genetic engineering methods have been used to create strains of microorganisms synthesizing eukaryotic proteins, including hormones and their precursors. The first stage of such developments is the isolation of DNA coding the des~red product. We have accomplished the cloning of the cDNA of a number of polypeptide and peptide hormones of the pituitary of man and domestic animals. The model gene of human calcitonin has also been synthesized and cloned. The obtained genes are being used to develop methods for the microbiological synthesis of human and animal-hormones