Influence of acute caffeine on 50-kHz ultrasonic vocalizations in male adult rats and relevance to caffeine-mediated psychopharmacological effects

To further characterize caffeine-mediated psychopharmacological effects, the present study investigated whether acute caffeine (3, 10, 30, 50 mg/kg i.p.) exerted any influence on the emission and features of ultrasonic vocalizations (USVs), which are thought to index changes involving emotional state, in male adult rats. The results obtained demonstrate that caffeine can trigger modifications in the maximum peak frequency and bandwidth of the 50-kHz range USVs. However, such an effect was not accompanied by a significant elevation in the number of 50-kHz USVs, relative to administration of vehicle. Under the same experimental conditions, acute amphetamine (2 mg/kg i.p.) robustly elevated the number of 50-kHz USVs emitted by rats, although it did not affect the maximum peak frequency and bandwidth of USVs. Thus, both qualitative and quantitative differences in the effects exerted by caffeine and amphetamine on 50-kHz USVs were observed. Taken together, these findings further clarify the features of caffeine-mediated psychopharmacological effects, and may help to elucidate the differences between the central effects of caffeine and those elicited by other psychostimulant

A Systematic Search for Corotating Interaction Regions in Apparently Single Galactic Wolf-Rayet Stars. II. A Global View of the Wind Variability

This study is the second part of a survey searching for large-scale spectroscopic variability in apparently single Wolf-Rayet (WR) stars. In a previous paper (Paper I), we described and characterized the spectroscopic variability level of 25 WR stars observable from the northern hemisphere and found 3 new candidates presenting large-scale wind variability, potentially originating from large-scale structures named Co-rotating Interaction Regions (CIRs). In this second paper, we discuss an additional 39 stars observable from the southern hemisphere. For each star in our sample, we obtained 4-5 high-resolution spectra with a signal-to-noise ratio of ~100 and determined its variability level using the approach described in Paper I. In total, 10 new stars are found to show large-scale spectral variability of which 7 present CIR-type changes (WR 8, WR 44, WR 55, WR 58, WR 61, WR 63, WR 100). Of the remaining stars, 20 were found to show small-amplitude changes and 9 were found to show no spectral variability as far as can be concluded from the data in hand. Also, we discuss the spectroscopic variability level of all single galactic WR stars that are brighter than v~12.5, and some WR stars with 12.5 < v <= 13.5; i.e. all the stars presented in our two papers and 4 more stars for which spectra have already been published in the literature. We find that 23/68 stars (33.8 %) present large-scale variability, but only 12/54 stars (~22.1 %) are potentially of CIR-type. Also, we find 31/68 stars (45.6 %) that only show small-scale variability, most likely due to clumping in the wind. Finally, no spectral variability is detected based on the data in hand for 14/68 (20.6 %) stars. Interestingly, the variability with the highest amplitude also have the widest mean velocity dispersion.Comment: 14 pages, 24 figures, 2 tables, Accepted in Ap

Polarimetric modeling of corotating interaction regions (CIRs) threading massive-star winds

Massive star winds are complex radiation-hydrodynamic (sometimes magnetohydrodynamic) outflows that are propelled by their enormously strong luminosities. The winds are often found to be structured and variable, but can also display periodic or quasi-periodic behavior in a variety of wind diagnostics. The regular variations observed in putatively single stars, especially in UV wind lines, have often been attributed to corotating interaction regions (CIRs) like those seen in the solar wind. We present light curves for variable polarization from winds with CIR structures. We develop a model for a time-independent CIR based on a kinematical description. Assuming optically thin electron scattering, we explore the range of polarimetric light curves that result as the curvature, latitude, and number of CIRs are varied. We find that a diverse array of variable polarizations result from an exploration of cases. The net polarization from an unresolved source is weighted more toward the inner radii of the wind. Given that most massive stars have relatively fast winds compared to their rotation speeds, CIRs tend to be conical at inner radii, transitioning to a spiral shape at a few to several stellar radii in the wind. Winds with a single CIR structure lead to easily identifiable polarization signatures. By contrast allowing for multiple CIRs, all emerging from a range of azimuth and latitude positions at the star, can yield complex polarimetric behavior. Although our model is based on some simplifying assumptions, it produces qualitative behavior that we expect to be robust, and this has allowed us to explore a wide range of CIR configurations that will prove useful for interpreting polarimetric data.Comment: accepted to A&