2,408 research outputs found

    Isolation characteristics of space telescope suspension systems Final technical report

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    Vibration isolation tests of spring, hysteresis, and magnetic suspension systems for spaceborne telescope

    Modeling and Simulation Techniques Used in High Strain Rate Projectile Impact

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    A series of computational models and simulations were conducted for determining the dynamic responses of a solid metal projectile impacting a target under a prescribed high strain rate loading scenario in three-dimensional space. The focus of this study was placed on two different modeling techniques within finite element analysis available in the Abaqus software suite. The first analysis technique relied heavily on more traditional Lagrangian analysis methods utilizing a fixed mesh, while still taking advantage of the finite difference integration present under the explicit analysis approach. A symmetry reduced model using the Lagrangian coordinate system was also developed for comparison in physical and computational performance. The second analysis technique relied on a mixed model that still made use of some Lagrangian modeling, but included smoothed particle hydrodynamics techniques as well, which are mesh free. The inclusion of the smoothed particle hydrodynamics was intended to address some of the known issues in Lagrangian analysis under high displacement and deformation. A comparison of the models was first performed against experimental results as a validation of the models, then the models were compared against each other based on closeness to experimentation and computational performance

    Internal versus external determinants of Schistosoma japonicum transmission in irrigated agricultural villages

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    Currently schistosomiasis transmission has been suppressed to low levels in many historically endemic areas of China by widespread use of praziquantel in human and bovine populations and application of niclosamide for snail control. However, re-emergent transmission has signalled the need for sustainable interventions beyond these repeated chemical interventions. To take advantage of ongoing investment in rural infrastructure, an index of schistosomiasis transmission potential is needed to identify villages where environmental modifications would be particularly effective. Based on a retrospective analysis of data from 10 villages in Sichuan Province, an index linked to the basic reproductive number is shown to have promise in meeting this need. However, a lack of methods for estimating the spatial components of the proposed metric and for estimating the import of cercariae and miracidia from neighbouring villages leads to significant uncertainty in its estimation. These findings suggest a priority effort to develop methods for measuring the free-swimming forms of the parasite in surface waters. This need is underscored by the high cost and limited sensitivity of current methods for diagnosing human infection and mounting evidence of the inadequacy of snail surveys to identify environments supporting low levels of transmission

    Computational Based Investigation of Lattice Cell Optimization under Uniaxial Compression Load

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    Structural optimization is a methodology used to generate novel structures within a design space by finding a maximum or minimum point within a set of constraints. Topology optimization, as a subset of structural optimization, is often used as a means for light-weighting a structure while maintaining mechanical performance. This article presents the mathematical basis for topology optimization, focused primarily on the Bi-directional Evolutionary Structural Optimization (BESO) and Solid Isotropic Material with Penalization (SIMP) methodologies, then applying the SIMP methodology to a case study of additively manufactured lattice cells. Three lattice designs were used: the Diamond, I-WP, and Primitive cells. These designs are all based on Triply Periodic Minimal Surfaces (TPMS). Individual lattice cells were subjected to a uniaxial compression load, then optimized for these load conditions. The optimized cells were then compared to the base cell designs, noting changes in the stress field response, and the maximum and minimum stress values. Overall, topology optimization proved its utility under this loading condition, with each cell seeing a net gain in performance when considering the volume reduction. The I-WP lattice saw a significant stress reduction in conjunction with the mass and volume reduction, marking a notable increase in cell performance

    Evaluation of Mammalian and Intermediate Host Surveillance Methods for Detecting Schistosomiasis Reemergence in Southwest China

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    Schistosomiasis has reemerged in China in regions where it was previously controlled. As reductions in schistosomiasis, a water-born parasitic infection, prompt consideration of schistosomiasis elimination, surveillance strategies that can signal reemergence and prevent further lapses in control are needed. We examined the distribution of Schistosoma japonicum, the species that causes schistosomiasis in China, in 53 villages. The villages were located in regions of Sichuan province where schistosomiasis reemergence had been documented by public health authorities. We tested three key reservoirs, humans, cows and water buffalo, and freshwater snails for S. japonicum infection in an effort to identify high-risk populations and evaluate their ability to signal reemergence. Human and bovine infections were common, detected in 35 villages and 23 villages, respectively, but infected snails were rare, found in only one village. Two commonly used surveillance methods, hospital reports of acute schistosomiasis and surveys for S. japonicum-infected snails, grossly underestimated the number of villages where human infections were present. Schistosomiasis was widespread in the region we studied, highlighting the danger reemergence poses to disease elimination programs. Surveillance systems that monitor high-risk populations such as older adults or bovine owners should be considered to promote detection of reemergence

    An Evaluation of Potential Occupational Exposure to Asbestiform Amphiboles near a Former Vermiculite Mine

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    Amphibole asbestos (AA) has been detected on the surface of tree bark in forests neighboring an abandoned vermiculite mine near Libby, Montana. In the present study, simulations were performed to assess potential AA exposure associated with United States Department of Agriculture Forest Service (FS) occupational activities. Bark samples were collected prior, and personal breathing zone (PBZ) and Tyvek clothing wipe samples were collected during and immediately after trials that simulated FS activities. Transmission electron microscopy (TEM) analyses revealed AA bark concentrations up to 15 million structures per square centimeter (s/cm2). AA was detected in 25% of the PBZ TEM samples. AA was detected on wipe samples collected from all activities evaluated. This research demonstrates the potential for airborne exposure and transport of AA in the Kootenai National Forest. These findings are especially relevant to those that work in the area and to the general public who may conduct recreational activities
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