1,360 research outputs found

    Governing through trust: community-based link workers and parental engagement in education

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    This article seeks to further understandings of contemporary patterns of parental government. Parenting has emerged as a key policy domain in twenty-first century Britain and we explore the politicisation of family life by examining a pilot programme tasked with enhancing parental engagement in education amongst ‘hard-to-reach’ families within the white British community of a large inner-London borough. Concentrating upon the programme’s signature device – the deployment of community-based ‘link workers’ to bridge home and school – ‘governmentality’ (Foucault, 2009) is used as a theoretical lens through which to foreground the link workers’ role in governing parents. We draw on qualitative data collected from link workers, parents, and school leaders, to argue that link workers represent a mode of governmentality that privileges the instrumental use of trust to achieve strategic objectives, rather than coercive authority. The aim being to produce responsible, self-disciplined parents who act freely in accordance with normative expectations as to what constitutes ‘good’ parenting and effective parental support. As such, the article highlights the link workers’ role in (re)producing the ideal, neoliberal parent. However, governing through trust comes at the cost of being unable to firmly secure desired outcomes. We thereby conclude that this gentle art of parental government affords parents some latitude in resisting institutional agendas

    Classifying faces by sex is more accurate with 3D shape information than with texture

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    Purpose: We compared quality of information available in 3D surface models versus texture maps for classifying human faces by sex. Methods: 3D surface models and texture maps from laser scans of 130 human heads (65 male, 65 female) were analyzed with separate principal components analyses (PCAs). Individual principal components (PCs) from the 3D head data characterized complex structural differences between male and female heads. Likewise, individual PCs in the texture analysis contrasted characteristically male vs. female texture patterns (e.g., presence/absence of facial hair shadowing). More formally, representing faces with only their projection coefficients onto the PCs, and varying the subspace from 1 to 50 dimensions, we trained a series of perceptrons to predict the sex of the faces using either the 3D or texture data. A "leave-one-out" technique was applied to measure the gen-eralizability of the perceptron's sex predictions. Results: While very good sex generalization performance was obtained for both representations, even with very low dimensional subspaces (e.g., 76.1 correct with only one 3D projection coefficient), the 3D data supported more accurate sex classification across nearly the entire range of subspaces tested. For texture, 93.8 correct sex generalization was achieved with a minimun subspace of 20 projection coefficients. For 3D data, 96.9 correct generalization was achieved with 17 projection coefficients. Conclusions: These data highlight the importance of considering the kinds of information available in different face representations with respect to the task demands

    Primal-dual coding to probe light transport

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    We present primal-dual coding, a photography technique that enables direct fine-grain control over which light paths contribute to a photo. We achieve this by projecting a sequence of patterns onto the scene while the sensor is exposed to light. At the same time, a second sequence of patterns, derived from the first and applied in lockstep, modulates the light received at individual sensor pixels. We show that photography in this regime is equivalent to a matrix probing operation in which the elements of the scene's transport matrix are individually re-scaled and then mapped to the photo. This makes it possible to directly acquire photos in which specific light transport paths have been blocked, attenuated or enhanced. We show captured photos for several scenes with challenging light transport effects, including specular inter-reflections, caustics, diffuse inter-reflections and volumetric scattering. A key feature of primal-dual coding is that it operates almost exclusively in the optical domain: our results consist of directly-acquired, unprocessed RAW photos or differences between them.Alfred P. Sloan Foundation (Research Fellowship)United States. Defense Advanced Research Projects Agency (DARPA Young Faculty Award)Massachusetts Institute of Technology. Media Laboratory (Consortium Members

    Epidermal grafting for wound healing: a review on the harvesting systems, the ultrastructure of the graft and the mechanism of wound healing

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    Epidermal grafting for wound healing involves the transfer of the epidermis from a healthy location to cover a wound. The structural difference of the epidermal graft in comparison to the split-thickness skin graft and full-thickness skin graft contributes to the mechanism of effect. While skin grafting is an epidermal transfer, little is known about the precise mechanism of wound healing by epidermal graft. This paper aims to explore the evolution of the epidermal graft harvesting system over the last five decades, the structural advantages of epidermal graft for wound healing and the current hypotheses on the mechanism of wound healing by epidermal graft. Three mechanisms are proposed: keratinocyte activation, growth factor secretion and reepithelialisation from the wound edge. We evaluate and explain how these processes work and integrate to promote wound healing based on the current in vivo and in vitro evidence. We also review the ongoing clinical trials evaluating the efficacy of epidermal graft for wound healing. The epidermal graft is a promising alternative to the more invasive conventional surgical techniques as it is simple, less expensive and reduces the surgical burden for patients in need of wound coverage

    Optical computing for fast light transport analysis

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    The molecular genetic analysis of the expanding pachyonychia congenita case collection

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    BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis. It is caused by mutations in one of five keratin genes: KRT6A, KRT6B, KRT6C, KRT16 or KRT17. OBJECTIVES: To identify mutations in 84 new families with a clinical diagnosis of PC, recruited by the International Pachyonychia Congenita Research Registry during the last few years. METHODS: Genomic DNA isolated from saliva or peripheral blood leucocytes was amplified using primers specific for the PC-associated keratin genes and polymerase chain reaction products were directly sequenced. RESULTS: Mutations were identified in 84 families in the PC-associated keratin genes, comprising 46 distinct keratin mutations. Fourteen were previously unreported mutations, bringing the total number of different keratin mutations associated with PC to 105. CONCLUSIONS: By identifying mutations in KRT6A, KRT6B, KRT6C, KRT16 or KRT17, this study has confirmed, at the molecular level, the clinical diagnosis of PC in these families

    Field Screening for Drought Tolerance in Crop Plants with Emphasis on Rice Proceedings of an International Workshop on Field Screening for Drought Tolerance in Rice 11-14 Dec 2000

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    There are two options for the management of crops in water l imi t ing environments: the agronomic and the genetic management. Wi t h the genetic management option droughttolerant varieties, once developed, would be a low economic input technology that woul d be readily acceptable to resource-poor, rainfed, small land holding farmers. Development of this genetic management technology requires robust, reproducible, simple, and rapid f ield, pot, and laboratory screening methods for identification of traits of drought tolerance in germplasm, and incorporation of the same in high-yielding varieties using conventional and biotechnological tools. Scientists working in various national and international crop drought research programs use different methods of screening appropriate to the crops on which they work, and keeping in view their target drought environment. This workshop focused on the methods used in different cereal (including rice) and legume crops. The rationale for the use of various methods and their advantages and disadvantages (if any) were discussed. Papers contributed by the participants, either as ful l papers or only abstracts of their paper, are included in this book. An overview and synthesis of the workshop and crop drought research in general is presented in the final chapter of the book

    OvHV-2 glycoprotein B delivered by a recombinant BoHV-4 is immunogenic and induces partial protection against sheep-associated malignant catarrhal fever in a rabbit model

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    An efficacious vaccine for sheep-associated malignant catarrhal fever (SA-MCF) is important for the livestock industry. Research towards SA-MCF vaccine development is hindered by the absence of culture systems to propagate the causative agent, ovine herpesvirus-2 (OvHV-2), which means its genome cannot be experimentally modified to generate an attenuated vaccine strain. Alternative approaches for vaccine development are needed to deliver OvHV-2 antigens. Bovine herpesvirus 4 (BoHV-4) has been evaluated as a vaccine vector for several viral antigens with promising results. In this study, we genetically engineered BoHV-4 to express OvHV-2 glycoprotein B (gB) and evaluated its efficacy as an SA-MCF vaccine using a rabbit model. The construction of a viable recombinant virus (BoHV-4-ADTK-OvHV-2-gB) and confirmation of OvHV-2 gB expression were performed in vitro. The immunization of rabbits with BoHV-4-ADTK-OvHV-2-gB elicited strong humoral responses to OvHV-2 gB, including neutralizing antibodies. Following intra-nasal challenge with a lethal dose of OvHV-2, 42.9% of the OvHV-2 gB vaccinated rabbits were protected against SA-MCF, while all rabbits in the mock-vaccinated group succumbed to SA-MCF. Overall, OvHV-2 gB delivered by the recombinant BoHV-4 was immunogenic and partly protective against SA-MCF in rabbits. These are promising results towards an SA-MCF vaccine; however, improvements are needed to increase protection rates
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