Effect of blood glucose level on standardized uptake value (SUV) in F-18- FDG PET-scan : a systematic review and meta-analysis of 20,807 individual SUV measurements

Objectives To evaluate the effect of pre-scan blood glucose levels (BGL) on standardized uptake value (SUV) in F-18-FDG-PET scan. Methods A literature review was performed in the MEDLINE, Embase, and Cochrane library databases. Multivariate regression analysis was performed on individual datum to investigate the correlation of BGL with SUVmax and SUVmean adjusting for sex, age, body mass index (BMI), diabetes mellitus diagnosis, F-18-FDG injected dose, and time interval. The ANOVA test was done to evaluate differences in SUVmax or SUVmean among five different BGL groups (200 mg/dl). Results Individual data for a total of 20,807 SUVmax and SUVmean measurements from 29 studies with 8380 patients was included in the analysis. Increased BGL is significantly correlated with decreased SUVmax and SUVmean in brain (p <0.001, p <0.001,) and muscle (p <0.001, p <0.001) and increased SUVmax and SUVmean in liver (p = 0.001, p = 0004) and blood pool (p=0.008, p200 mg/dl had significantly lower SUVmax. Conclusion If BGL is lower than 200mg/dl no interventions are needed for lowering BGL, unless the liver is the organ of interest. Future studies are needed to evaluate sensitivity and specificity of FDG-PET scan in diagnosis of malignant lesions in hyperglycemia.Peer reviewe

Applications for solar irradiance nowcasting in the control of microgrids: A review

The integration of solar photovoltaic (PV) into electricity networks introduces technical challenges due to varying PV output. Rapid ramp events due to cloud movements are of particular concern for the operation of remote islanded microgrids (MGs) with high penetration of solar PV generation. PV plants and optionally controllable distributed energy resources (DERs) in MGs can be operated in an optimized way based on nowcasting, which is also called very short-term solar irradiance forecasting up to 60 min ahead. This study presents an extensive literature review on nowcasting technologies along with their current and future possible applications in the control of MGs. Ramp rates control and scheduling of spinning reserves are found to be the most recognized applications of nowcasting in MGs. An online survey has been conducted to identify the limitations, benefits and challenges of deploying nowcasting in MGs. The survey outcomes show that the incorporation of nowcasting tools in MG operations is still limited, though the possibility of increasing solar PV penetration levels in MGs if nowcasting tools are incorporated is acknowledged. Additionally, recent nowcasting tools, such as sky camera-based tools, require further validation under various conditions for more widespread adaptation by power system operators