Numerical treatment of the Filament Based Lamellipodium Model (FBLM)

We describe in this work the numerical treatment of the Filament Based Lamellipodium Model (FBLM). The model itself is a two-phase two-dimensional continuum model, describing the dynamics of two interacting families of locally parallel F-actin filaments. It includes, among others, the bending stiffness of the filaments, adhesion to the substrate, and the cross-links connecting the two families. The numerical method proposed is a Finite Element Method (FEM) developed specifically for the needs of these problem. It is comprised of composite Lagrange-Hermite two dimensional elements defined over two dimensional space. We present some elements of the FEM and emphasise in the numerical treatment of the more complex terms. We also present novel numerical simulations and compare to in-vitro experiments of moving cells

Geometric realizations of generalized algebraic curvature operators

We study the 8 natural GL equivariant geometric realization questions for the space of generalized algebraic curvature tensors. All but one of them is solvable; a non-zero projectively flat Ricci antisymmetric generalized algebraic curvature is not geometrically realizable by a projectively flat Ricci antisymmetric torsion free connection

Behavioral Predictors of Colonization with Lactobacillus crispatus or Lactobacillus jensenii after Treatment for Bacterial Vaginosis: A Cohort Study

Objective: Evaluate predictors of vaginal colonization with lactobacilli after treatment for bacterial vaginosis (BV). Methods. Vaginal fluid specimens from women with BV underwent qPCR for Lactobacillus crispatus, L. jensenii, and L. iners pre- and posttreatment. Results. Few women with BV were colonized with L. crispatus (4/44, 9%) or L. jensenii (1/44, 2%), though all had L. iners. One month posttreatment 12/44 (27%) had L. crispatus, 12/44 (27%) L. jensenii, and 43/44 (98%) L. iners. Presence of L. jensenii posttreatment was associated with cure (Risk Ratio (RR) 1.67; 95% CI 1.09–2.56); L. crispatus showed a similar trend (RR 1.41; 95% CI 0.89–2.24, P = 0.14). Receptive oral sex was associated with 2.2-log10 lower concentration of L. crispatus (95% CI −4.38, −.02), and digital-vaginal sex with 2.6-log10 lower concentration (95% CI −4.87, −.33). Conclusion. One month after BV treatment, few women established colonization with L. crispatus or L. jensenii. Few behaviors were associated with colonization

Effect of the Predecessor and the Nitrogen Rate on Productivity and Essential Oil Content of Coriander (Coriandrum sativum L.) in Southeast Bulgaria

Received: May 31st, 2022 ; Accepted: August 13th, 2022 ; Published: September 19th, 2022 ; Correspondence: [email protected] (Coriandrum sativum L.) is one of the most important essential oil crops on a global scale. Coriander productivity is determined by the genotype, the environmental factors, as well the agronomic practices. A field experiment was conducted in Southeast Bulgaria during three vegetation seasons (2015, 2016, and 2017). The present study aimed at analysing the influence of two crop predecessors (winter wheat and sunflower) and four nitrogen (N) levels (0, 40, 80, and 120 kg ha-1 ). Productivity elements, seed yield, and seed essential oil content of coriander (cv. Mesten drebnoploden) were under evaluation. The results obtained showed that winter wheat was a more suitable predecessor of coriander in comparison to sunflower. The highest results regarding the number of umbels per plant, the umbel’s diameter, the number of umbellets per umbel, the number of seeds per umbel, the seed weight per plant, the 1,000 seed mass, as well as the seed yield for the rate of 80 kg ha-1 of N were recorded. The highest essential oil content after applying 120 kg ha-1 of N was established. Increasing the N level from 0 to 120 kg ha-1 led to a positive and significant effect on essential oil yield. No significant differences between the N rates of 80 and 120 kg ha-1 were recorded. The received results contributed for the evaluatation of the optimum nitrogen level, as well as for the determination of a more suitable predecessor of coriander in order to obtain the highest yield of better quality in the region of Southeast Bulgaria

Compressional and Shear Waves Tests Through Upper Sheet of Low Angle Thrust Fault

Compressional and shear wave tests were conducted on the upper thrust sheet of the low angle Little Salmon thrust fault. The study was conducted on the campus of the College of the Redwoods. The campus is located approximately 8 miles south of Eureka and 24 miles north-northeast of Cape Mendocino and the Mendocino Triple Junction (MTJ) in Northern California. The MTJ is the point of transition from strike-slip faulting of the San Andreas transform system to low-angle reverse (thrust) faulting and folding associated with the convergent margin of the Cascadia Subduction Zone. The campus is located on the southwest limb of the Humboldt Hill anticline, one of the folds in the fold and thrust belt. The Little Salmon fault zone is a low angle thrust fault that day lights on the south side of the campus and then projects underneath striking northwest and dipping northeast. A boring was drilled down to the fault plane located at a depth of 200 ft. in the upper thrust block to develop a mode1 of the stratification as well as the material properties. The boring also revealed the trunk of a redwood tree located at a depth of 180 feet. Results of compressional and shear wave velocities as a function of depth that were determined using an downhole geophysical technique. Results indicated two shear wave velocity units. Unit 1 was from 0 to 120 ft. with a shear wave velocity ranging from 950- 1400 fps. Unit 2 ranged from 120 to 190 ft. with a shear wave velocity ranging from 2300 to 2600 fps. Compression wave velocity measurements obtained from the same test boring also depict a change in velocity in the 100 to 120 foot range. A response spectra was generated based on this in-situ mode1 using SHARE91 and compared against one developed using the Boore, Joyner and Fumal empirical model

Maximum Likelihood Estimation of Head Motion Using Epipolar Consistency

Open gantry C-arm systems that are placed within the interventional room enable 3-D imaging and guidance for stroke therapy without patient transfer. This can profit in drastically reduced time-totherapy, however, due to the interventional setting, the data acquisition is comparatively slow. Thus, involuntary patient motion needs to be estimated and compensated to achieve high image quality. Patient motion results in a misalignment of the geometry and the acquired image data. Consistency measures can be used to restore the correct mapping to compensate the motion. They describe constraints on an idealized imaging process which makes them also sensitive to beam hardening, scatter, truncation or overexposure. We propose a probabilistic approach based on the Student’s t-distribution to model image artifacts that affect the consistency measure without sourcing from motion

Probabilistic Estimation of Site Specific Fault Displacements

The College of the Redwoods (CR) located near Eureka, California would like to upgrade a series of existing buildings that are unfortunately located on secondary faults associated with the active Little Salmon Fault (LSF) zone. In the early 1990’s a deterministic value of the maximum dip-slip displacement that had occurred on one of these secondary faults located beneath the southeast building corner of the former library was measured to be 1.7 feet. This displacement was resolved into approximately 1.5 feet horizontal offset and 0.8 feet of vertical offset, based on the secondary fault plane dip. Geologically, it has not been possible to establish the actual dates of the occurrence of the displacements on the observed faults, therefore it was assumed that they all had occurred within the last 11,000 years. The structural engineer for the project has indicated that it was not possible to design for the observed ground displacement of 1.7 feet. This limited study was undertaken to assess the variation of ground displacements that were observed over the area of ground occupied by CR’s Administration, Science, and former Library buildings. The purpose of this study was to evaluate the reasonableness of using a deterministically determined maximum value of displacement in estimating, and designing mitigations for, the structural response, or whether a probabilistic approach could be utilized. The only data available within the limited time frame allowed for the study was from a series of trench logs made as part of a project for locating building sites on the campus in the early 1990’s. As a first step the frequency distributions of both horizontal and vertical displacements located in a volume of soil comprising the area occupied by the above buildings to a depth of 14 feet were examined. The 14 feet was the maximum depth of the trenches used to provide data for the study. Probability density functions (PDF) versus displacements were developed based on the frequency distributions. The area under the PDF curves between given displacement intervals represents the probability of occurrence (POC) of that displacement. A cumulative probability of occurrence for a displacement interval can be determined by adding the individual POC’s. Based on this it was estimated that a horizontal displacement of ≤ 1.0 foot has a probability of 89% of occurring in the next 11,000 years at the site. In contrast, a vertical displacement of ≤ 1.0 foot has a probability of 88% probability of occurrence

Use of Microzonation to Site Facility on Low Angle Thrust and Associated Fault Bend Folding

The campus of the College of the Redwoods is located completely within the Little Salmon Fault Zone, designated by the State of California as an active fault. The College has been extensively investigated for fault rupture and other seismic hazards in 1989, 1993, 1997, 1998, and 1999. The Little Salmon Fault Zone bounds the College and consists of two main northwest-striking, northeastdipping, low-angle thrusts. The west splay daylights along the southwest edge of the campus and projects beneath it. A recurrence interval of 268 years and slip rate of 5+/-3 mm/yr is estimated by CDMG. Individual dip-slip displacements along the west trace are reported to be 12 to 15 feet (3.6 to 4.5 m). Movement on the Little Salmon fault (LSF) is accompanied by growth of broad asymmetric folds in the upper thrust sheet resulting in surface rupture, localized uplift and discreet fault-bend fold axial surfaces. College of the Redwoods is located approximately 8 miles (13 km) south of Eureka and 25 miles (40 km) north-northeast of Cape Mendocino and the Mendocino Triple Junction (MTJ) in northern California. The \u27MTJ is the point of transition fi-om strike-slip faulting of the San Andreas transform system to low-angle thrust faulting and folding associated with the convergent margin of the Cascadia Subduction Zone. Campus infrastructure is located along the base of the Humboldt Hill Anticline (HHA), a major faultbend fold of the Cascadia fold and thrust belt. A new learning resource center (LRC) is proposed for a location 400 feet (120 m) northeast of where the west trace of the LSF daylights and 200 feet (60 m) above the low-angle fault plane. Building setback and design recommendations to mitigate for both fault rupture hazards and fault-generated folding hazards are presented

Three-year randomised clinical trial to evaluate the clinical performance, quantitative and qualitative wear patterns of hybrid composite restorations

The aim of the study was to compare the clinical performance, quantitative and qualitative wear patterns of conventional hybrid (Tetric Ceram), micro-filled hybrid (Gradia Direct Posterior) and nano-hybrid (Tetric EvoCeram, TEC) posterior composite restorations in a 3-year randomised clinical trial. Sixteen Tetric Ceram, 17 TEC and 16 Gradia Direct Posterior restorations were placed in human molars and evaluated at baseline, 6, 12, 24 and 36 months of clinical service according to US Public Health Service criteria. The gypsum replicas at each recall were used for 3D laser scanning to quantify wear, and the epoxy resin replicas were observed under scanning electron microscope to study the qualitative wear patterns. After 3 years of clinical service, the three hybrid restorative materials performed clinically well in posterior cavities. Within the observation period, the nano-hybrid and micro-hybrid restorations evolved better in polishability with improved surface gloss retention than the conventional hybrid counterpart. The three hybrid composites showed enamel-like vertical wear and cavity-size dependant volume loss magnitude. Qualitatively, while the micro-filled and nano-hybrid composite restorations exhibited signs of fatigue similar to the conventional hybrid composite restorations at heavy occlusal contact area, their light occlusal contact areas showed less surface pitting after 3 years of clinical service

Bigger, Better, Faster, More at the LHC

Multijet plus missing energy searches provide universal coverage for theories that have new colored particles that decay into a dark matter candidate and jets. These signals appear at the LHC further out on the missing energy tail than two-to-two scattering indicates. The simplicity of the searches at the LHC contrasts sharply with the Tevatron where more elaborate searches are necessary to separate signal from background. The searches presented in this article effectively distinguish signal from background for any theory where the LSP is a daughter or granddaughter of the pair-produced colored parent particle without ever having to consider missing energies less than 400 GeV.Comment: 26 pages, 8 Figures. Minor textual changes, typos fixed and references adde