The ionizing sources of luminous compact HII regions in the RCW106 and RCW122 clouds

Given the rarity of young O star candidates, compact HII regions embedded in dense molecular cores continue to serve as potential sites to peer into the details of high-mass star formation. To uncover the ionizing sources of the most luminous and compact HII regions embedded in the RCW106 and RCW122 giant molecular clouds, known to be relatively nearby (2-4 kpc) and isolated, thus providing an opportunity to examine spatial scales of a few hundred to a thousand AU in size. High spatial resolution (0.3"), mid-infrared spectra (R=350), including the fine structure lines [ArIII] and [NeII], were obtained for four luminous compact HII regions, embedded inside the dense cores within the RCW106 and RCW122 molecular cloud complexes. At this resolution, these targets reveal point-like sources surrounded by nebulosity of different morphologies, uncovering details at spatial dimensions of <1000AU. The point-like sources display [ArIII] and [NeII] lines - the ratios of which are used to estimate the temperature of the embedded sources. The derived temperatures are indicative of mid-late O type objects for all the sources with [ArIII] emission. Previously known characteristics of these targets from the literature, including evidence of disk or accretion suggest that the identified sources may grow more to become early-type O stars by the end of the star formation process

Results from the EPL monkey-pod flight experiments conducted aboard the NASA/Ames CV-990, May 1976

The participation of the Environmental Physiology Laboratory (EPL) in the general purpose laboratory concept verification test 3 is documented. The EPL Monkey-Pod Experiment was designed to incorporate a 10-12 kg, pig tailed monkey, Macaca nemestrina, into the pod and measure the physiological responses of the animal continously. Four major elements comprise the EPL Monkey-Pod Experiment System: (1) a fiberglass pod containing the instrumented monkey plus feeder and watering devices, (2) an inner console containing the SKYLAB mass spectrometer with its associated valving and electronic controls, sensing, control and monitoring units for lower body negative pressure, feeder activity, waterer activity, temperatures, and gas metabolism calibration, (3) an umbilical complex comprising gas flow lines and electrical cabling between the inner and outer console and (4) an outer console in principle representing the experiment support to be provided from general space craft sources

Results from the EPL monkey-pod experiment conducted as part of the 1974 NASA-Ames CVT/GPL 3

For abstract, see vol. 2

Results from the EPL monkey-pod experiment conducted as part of the 1974 NASA/Ames shuttle CVT-2

The participation of the Environmental Physiology Laboratory (EPL) in the general purpose laboratory concept verification test 3 is documented. The EPL Monkey-Pod Experiment was designed to incorporate a 10-12 kg, pig tailed monkey, Macaca nemestrina, into the pod and measure the physiological responses of the animal continuously. Four major elements comprise the EPL Monkey-Pod Experiment System: (1) a fiberglass pod containing the instrumented monkey plus feeder and watering devices, (2) an inner console containing the SKYLAB mass spectrometer with its associated valving and electronic controls, sensing, control and monitoring units for lower body negative pressure, feeder activity, waterer activity, temperatures, and gas metabolism calibration, (3) an umbilical complex comprising gas flow lines and electrical cabling between the inner and outer console and (4) an outer console in principle representing the experiment support to be provided from general spacecraft sources

Glitches in Southern Pulsars

Timing observations of 40 mostly young pulsars using the ATNF Parkes radio telescope between 1990 January and 1998 December are reported. In total, 20 previously unreported glitches and ten other glitches were detected in 11 pulsars. These included 12 glitches in PSR J1341$-$6220, corresponding to a glitch rate of 1.5 glitches per year. We also detected the largest known glitch, in PSR J1614$-$5047, with $\Delta\nu_g/\nu \approx 6.5 \times 10^{-6}$ where $\nu = 1/P$ is the pulse frequency. Glitch parameters were determined both by extrapolating timing solutions to inter-glitch intervals and by phase-coherent timing fits across the glitch(es). Analysis of glitch parameters, both from this work and from previously published results, shows that most glitches have a fractional amplitude $\Delta\nu_g/\nu$ of between $10^{-8}$ and $10^{-6}$. There is no consistent relationship between glitch amplitude and the time since the previous glitch or the time to the following glitch, either for the ensemble or for individual pulsars. As previously recognised, the largest glitch activity is seen in pulsars with ages of order 10$^4$ years, but for about 30 per cent of such pulsars, no glitches were detected in the 8-year data span. There is some evidence for a new type of timing irregularity in which there is a significant increase in pulse frequency over a few days, accompanied by a decrease in the magnitude of the slowdown rate. Fits of an exponential recovery to post-glitch data show that for most older pulsars, only a small fraction of the glitch decays. In some younger pulsars, a large fraction of the glitch decays, but in others, there is very little decay.Comment: 19 pages, 20 figures. Accepted for publication in MNRA

Metabolic and cardiovascular adaptation, monkey. NASA SMD 3, project 76, experiment 44 conducted at NASA/JSC, 14-25 May 1977

The biomedical results from an experiment on a monkey subjected to space flight conditions are reported. A background history of the development and testing of an experiment system designed to permit measurement of physiological parameters in subhuman primates during continuous, comfortable, couch restraint for periods of up to 30 days is reviewed. Of major importance in the experimental design of the system was the use of a fiberglass pod, which could be sealed and subdivided into upper and lower parts, to monitor and control the physiological responses for various parts of the animal's body. The experiment was conducted within the Spacelab Simulator for a period of 11 days. Data recorded includes: Spacelab Simulator cabin temperature; ventilation rate; pod internal temperature; fraction percent oxygen; fraction percent carbon dioxide; oxygen consumption rate; carbon dioxide production rate; respiratory quotient; intrathoracic temperature; heart rate; mean aortic pressure; mean ventricular pressure; diurnal variation of parameters measured; comparison of mean preflight, flight, and postflight values of the parameters measured; and correlation matrix for the parameters measured

Dilated Convolutional Neural Networks for Cardiovascular MR Segmentation in Congenital Heart Disease

We propose an automatic method using dilated convolutional neural networks (CNNs) for segmentation of the myocardium and blood pool in cardiovascular MR (CMR) of patients with congenital heart disease (CHD). Ten training and ten test CMR scans cropped to an ROI around the heart were provided in the MICCAI 2016 HVSMR challenge. A dilated CNN with a receptive field of 131x131 voxels was trained for myocardium and blood pool segmentation in axial, sagittal and coronal image slices. Performance was evaluated within the HVSMR challenge. Automatic segmentation of the test scans resulted in Dice indices of 0.80$\pm$0.06 and 0.93$\pm$0.02, average distances to boundaries of 0.96$\pm$0.31 and 0.89$\pm$0.24 mm, and Hausdorff distances of 6.13$\pm$3.76 and 7.07$\pm$3.01 mm for the myocardium and blood pool, respectively. Segmentation took 41.5$\pm$14.7 s per scan. In conclusion, dilated CNNs trained on a small set of CMR images of CHD patients showing large anatomical variability provide accurate myocardium and blood pool segmentations

Toxicity and morbility after isolated lower limb perfusion in 242 chemo-hyperthermal treatments for cutaneous melanoma: The experience of the Tuscan Reference Centre

<p>Abstract</p> <p>Background</p> <p>The aim of this retrospective study was to assess the results concerning the regional and systemic toxicity and complications in 242 chemo-hyperthermal treatments (HILPs) for lower limb melanoma.</p> <p>Patients and methods</p> <p>60 HILPs (G-A) were performed with mild HT plus L-PAM (10 mg/lt) ± D-actimomycin; 74 HILPs (G-B) with true HT (40–41.8°C) plus L-PAM (10 mg/lt) ± D-act; 108 HILPs (G-C) with true HT plus L-PAM (10 mg/lt) ± D-act plus L-PAM (5 mg/lt) additional bolus.</p> <p>Results</p> <p>Limb toxicity was very low in G-A and in G-B; increasing toxicity (grade III = 37%) in G-C; no grade IV statistical difference was registered in all three groups, with percentage values among 1.6% and 2.7%. Systemic toxicity showed itself only in the haemopoietic parameters. No differences were registered in G-B vs G-A group. In G-C vs G-B a significative increase of systemic toxicity was seen in grade 3 (p < 0.05). Postoperative complications were acceptable. Local and systemic side-effects were transient; no permanent neurological limb deficit was registered. The postoperative mortality was recorded in 3/182 HILPs (1.6%) of the G-B and G-C groups.</p> <p>Conclusion</p> <p>These data suggested that the technical implementations reduced the occurrence and the severity of the side effects and complications. The essential requirement for HILP is the quality assurance of the procedures. Although higher regional and systemic toxicity were observed in the G-C group caused by L-PAM additional bolus, the safeness of the procedures under the true hyperthermal regimen and the time increase of the high L-PAM concentration have assured the treatment reliability along with the increased clinical efficacy expectations of the treatments.</p

E-nose Development for Safety Monitoring Applications in Refinery Environment

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