Linear Phase Second Order Recursive Digital Integrators and Differentiators

In this paper, design of linear phase second order recursive digital integrators and differentiators is discussed. New second order integrators have been designed by using Genetic Algorithm (GA) optimization method. Thereafter, by modifying the transfer function of these integrators appropriately, new digital differentiators have been obtained. The proposed digital integrators and differentiators accurately approximate the ideal ones and have linear phase response over almost entire Nyquist frequency range. The proposed operators also outperform the existing operators in terms of both magnitude and phase response

FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF OMEPRAZOLE

Objective: The aim of present study is to formulate mouth dissolving tablet of omeprazole, the drug will be directly absorbed into systemic circulation through buccal mucosa and lead to produce immediate action. Methods: Mouth dissolving tablets of Omeprazole were prepared by wet granulation method. Required quantity of drug and other excipients were weighed and sieved from sieve no.60 for finding homogenous mixer, then a damp mass of mixer was prepared by using distilled water as a solvent, Damp mass was passed through sieve no. 10 and dried the granules at 50 °C till moisture remaining less than 2% Results: All the formulated tablets met the pharmacopoeias standard of uniformity of weight, percentage friability, thickness, and drug content. The in vitro disintegration and dispersion studies were also performed, which shows very good bioavailability and drug release profile. Accelerated stability studies were done for four weeks and found that no significant change in drug content and other parameters like hardness and in vitro dispersion time after four weeks even at 50 °C. It may be predicted that formulation will be stable for more than one year. Conclusion: The present investigation successfully formulated mouth dissolving tablets of omeprazole with improved drug release profile. The formulation was chosen because it showed good results in terms of cumulative drug release, disintegration time, hardness and friability. The dissolution study of this formulation showed an increase in the cumulative % drug release

Search for Quark-Lepton Compositeness at Tevatron and LHC

We make a Monte Carlo study on compositeness of first generation quarks and leptons using the Drell-Yan distribution in the high dielectron mass region at the Tevatron and LHC energies. The current experimental lower limits on the compositeness scale, \Lambda, vary from 2.5 to 6.1 TeV. In the present analysis, we assume that there will be no deviation of the dielectron mass spectrum from Standard Model prediction at center of mass energy 2 TeV (Tevatron) and 14 TeV (LHC). We then find that in the LL, RR, RL and LR chirality channels of the quark-electron currents, it is possible to extend the lower limits on \Lambda (at 95% {CL}) to a range of 6 to 10 TeV for 2 fb^{-1} and 9 to 19 TeV for 30 fb^{-1} of integrated luminosity at Tevatron. At LHC, the corresponding limits extend to a range of 16 to 25 TeV for 10 fb^{-1} and 20 to 36 TeV for 100 fb^{-1} of integrated luminosity

Coupled common fixed point theorems in partially ordered G-metric spaces for nonlinear contractions

The aim of this paper is to prove coupled coincidence and coupled common fixed point theorems for a mixed $g$-monotone mapping satisfying nonlinear contractive conditions in the setting of partially ordered $G$-metric spaces. Present theorems are true generalizations of the recent results of Choudhury and Maity [Math. Comput. Modelling 54 (2011), 73-79], and Luong and Thuan [Math. Comput. Modelling 55 (2012) 1601-1609]

Design and Performance of INMAS Whole Body Counter

A whole-body counter has been commissioned at INMAS for radiation protection and clinical applications including body potassium estimations. It has 4-crystal bed geometry inside a shielded enclosure. The background index of the system (counts) per minute per cc detector volume in the energy band 0.1-2 me V is about 0.6 comparing favorably with other whole-body monitors in the world. The sensitivity is 0.5 cpm per gram of K. Body potassium can be estimated can be estimated correct to 10 g for one hour counting. The variation in detector response to a point source on the mid-line of the bed is + - 10% of the mean over a length of 170 cm. The usefulness of the large dimensions of the enclosure chosen is discussed

Nutritional evaluation of protein isolate from rubber seed in the diet of Labeo rohita: Effects on growth performance, nutrient utilization, whole body composition and metabolic enzymes activity

A 45-days feeding trial was conducted to study the immunomodulatory effect and interferon gamma gene expression of dietary fucoidan rich seaweed extract (FRSE) from Sargassum wightii on Pangasianodon hypophthalmus fingerlings. One hundred and eighty fingerlings were distributed into six experimental groups in triplicates. Each group was stocked with 10 fish and fed to satiation with iso-nitrogenous (34.96 � 0.09–35.18 � 0.03 CP%) and iso-caloric (368.65 � 0.86–375.09 � 0.26 Kcal/100 g) purified diets containing either 0% FRSE (control), 1% FRSE (TF1), 2% FRSE (TF2), 3% FRSE (TF3), 3% seaweed powder (TS3) or 6% seaweed powder (TS6) in the feed. After feeding trial the experimental fish were challenged with Aeromonas hydrophila. Immunological parameters like respiratory burst activity, lysozyme activity, phagocytic activity and total leukocyte count (TLC) were increased with the increasing level of dietary FRSE, whereas serum Albumin/ Globulin (A/G) ratio and blood glucose level exhibited decreasing trend (P < 0.05)

Assessing heat vulnerability in London care settings: case studies of adaptation to climate change

This pilot study aims at testing methods to assess heat vulnerability in London care homes and develop overheating reduction strategies to mitigate temperature exposure and the associated negative health impacts under the warming climate, with a view to scaling up the project on a national scale. It undertakes feasibility work to identify possible causes of overheating across a range of care home types and evaluate the current and future potential of indicative passive solutions. The summertime thermal environments of five case study care homes were monitored and their physical, technical and occupancy profiles were established through surveys. The data was inputed in the EnergyPlus V8.9 dynamic thermal simulations via the DesignBuilder Graphical User Interface. Future overheating risks and their reduction potential through the use of passive strategies were tested under a set of representative climate change scenarios, during a five-day heatwave period. The dynamic thermal simulation analysis indicated that older buildings with higher heat loss and thermal mass capacities are likely to benefit more from the application of high albedo materials rather than external shading methods, whereas newer and highly insulated buildings seem to benefit more from higher ventilation rates and appropriate external shading systems. Night ventilation emerged as the single most impactful passive technique for all building types. This feasibility work has developed novel methods, knowledge and insights that will be helpful in understanding how to enable care settings in the UK to become resilient to rising heat stress. This is one of the first systematic attempts to build a set of dynamic thermal models of care homes in the UK