938 research outputs found

    An accuracy study of finite difference methods in structural analysis

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    Accuracy study of finite difference methods for solving boundary value problems in structural analysi

    Alien Registration- Gallant, Cyrus N. (Caribou, Aroostook County)

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    https://digitalmaine.com/alien_docs/26173/thumbnail.jp

    Circuit with a Switch for Charging a Battery in a Battery Capacitor Circuit

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    A circuit for charging a battery combined with a capacitor includes a power supply adapted to be connected to the capacitor, and the battery. The circuit includes an electronic switch connected to the power supply. The electronic switch is responsive to switch between a conducting state to allow current and a non-conducting state to prevent current flow. The circuit includes a control device connected to the switch and is operable to generate a control signal to continuously switch the electronic switch between the conducting and non-conducting states to charge the battery

    P. Falciparum Resisten Terhadap Chloroquine Di Kabupaten Jepara, Jawa Tengah

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    Twenty indigenous falciparum cases were subjected to either an in vivo and/or in-vitro (macro and micro) test, held during a WHO assisted training activity in Jepara, Central Jawa, in May 1981, to assess its susceptibility to chloroquine. Result showed that all cases were resistant to chloroquine. Ten cases underwent in-vivo test, revealing 9 resistant at RI and 1 resistant at RII level. This is the first report of falciparum found in Jawa

    Genetic contribution to radiographic severity in osteoarthritis of the knee

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    Objective Knee osteoarthritis (OA) has a significant genetic component. The authors have assessed the role of three variants reported to influence risk of knee OA with p<5×10–8 in determining patellofemoral and tibiofemoral Kellgren Lawrence (K/L) grade in knee OA cases. Methods 3474 knee OA cases with sky-line and weight-bearing antero-posterior x-rays of the knee were selected based on the presentation of K/L grade ≥2 at either the tibiofemoral or patellofemoral compartments for one or both knees. Patients belonging to three UK cohorts, were genotyped for rs143383, rs4730250 and rs11842874 mapping to the GDF5, COG5 and MCF2L genes, respectively. The association between tibiofemoral K/L grade and patellofemoral K/L grade was assessed after adjusting for age, gender and body mass index. Results No significant association was found between the rs4730250 and radiographic severity. The rs11842874 mapping to MCF2L was found to be nominally significantly associated with patellofemoral K/L grade as a quantitative trait (p=0.027) but not as a binary trait. The GDF5 single nucleotide polymorphism rs143383 was associated with tibiofemoral K/L grade (β=0.05 (95% CI 0.02 to 0.08) p=0.0011). Conclusions Our data indicate that within individuals affected by radiographic knee OA, OAGDF5 has a modest but significant effect on radiographic severity after adjustment for the major risk factors

    Capital Structure, Firm Efficiency and Firm Value: The Case of Listed Non-Financial Firms in Kenya

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    This study examined the influence of a firm’s efficiency on the relationship between capital structure and firm value. The study analyzed thirty non – financial firms listed at the Nairobi Securities Exchange for a period of six years from   2008 to 2013.Capital structure was parameterized as the ratio of retained earnings to total capital, ratio of debt to total capital and ratio of equity to total capital of the firm. Efficiency is measured as the distance from the best practice frontier in the industry. The firm’s efficiency is measured by operational efficiency, cost efficiency and profit efficiency. Firm value is measured by its inputs and outputs. The inputs to the firms production are financing costs (FINC), distribution costs (DISTC), tax liability (TAX), and administrative expenses (ADEXP). The outputs are earnings per share(EPS)and the share price (SP).This study applied panel data analysis using fixed effects model. The results showed that cost efficiency negatively influences the relationship between capital structure and firm value as measured by the SP through increase in distribution costs, administrative costs in financing efficiency improvements in the firm’s core processes. Further Operating efficiency negatively and statistically significantly affects the relationship between firm value and capital structure through the increase in financing costs, distribution costs, administration costs and taxation costs. The results showed that profit efficiency negatively and insignificantly influences the relationship between capital structure and firm value as measured by the SP. Consequently it has a positive but statistically insignificant effect on financing costs, distribution costs, administrative costs and taxation costs. Moreover, capital structure has a positive and statistically significant effect on firm value but firm efficiency insignificantly influences the relationship between capital structure and firm value. This study does not investigate the reverse relationship like Margaritis and Psillaki (2007). Keywords: Capital Structure, Firm Efficiency, Firm Value, Listed Non-Financial Firms, Nairobi Securities Exchang

    Progress in Diarrheal Disease Research at Namru-2 in Collaboration with Badan Litbangkes and Rspi

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    Penyakit diare termasuk kolera masih merupakan masalah kesehatan yang penting untuk Indonesia. Kejadian luar biasa (KLB) "muntah-berak" masih terus dilaporkan dari berbagai daerah di Indonesia. Salah satu upaya yang dilakukan untuk mengatasi keadaan ini adalah menemukan suatu vaksin yang aman, praktis dan terjangkau harganya. CVD-103 adalah strain V. cholerae yang sebagian besar gen penyebab diare, toksin subunit A, telah dibuang. Pada penelitian dengan peserta anak-anak di Jakarta, CVD 103-HgR ternyata memberikan kenaikan antibodi dan dapat diterima baik oleh anak-anak Indonesia berusia 5-9 tahun dan 25-59 bulan. Di samping itu pemeriksaan sampel bakteriologik dari lingkungan dekat tempat kediaman peserta dengan menggunakan teknik yang peka untuk mendeteksi V. cholerae, tidak menemukan adanya strain vaksin. Suatu penelitian lapangan dengan tujuan untuk menilai kemanjuran dosis tunggal vaksin oral kolera CVD 103-HgR untuk pencegahan kolera secara klinis selama tiga tahun, telah dimulai didaerah Jakarta Utara pada tahun 1993. Selain itu penelitian ini juga bertujuan untuk menetapkan kemanjuran vaksin terhadap berbagai kelompok umur, terhadap kolera berat, serta membandingkan kemanjurannya pada peserta dengan golongan darah O. Jumlah penduduk yang ikut dalam penilaian vaksin ini adalah 67.000 peserta sukarela. Hasil penelitian ini diharapkan dapat diketahui pada akhir tahun 1996.Di samping penelitian tentang vaksin kolera, NAMRU dan Badan Litbangkes juga telah ikut serta dalam berbagai penelitian WHO, misalnya tentang larutan garam oralit (ORS) yang dilakukan di RS Karantina/RS Penyakit Infeksi Prof. Dr. Sulianti Saroso. Salah satu penelitian terakhir adalah manfaat larutan ORS dengan osmolaritas rendah pada tahun 1994. Hasil penelitian ini telah mendorong WHO untuk melaksanakan penelitian dengan larutan yang sama di berbagai pusat penelitian (multicenter) pada tahun 1995 sebelum mengusulkan suatu Perubahan formulasi larutan ORS secara global
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