1,911 research outputs found

    Electromagnetic form factor via Minkowski and Euclidean Bethe-Salpeter amplitudes

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    The electromagnetic form factors calculated through Euclidean Bethe-Salpeter amplitude and through the light-front wave function are compared with the one found using the Bethe-Salpeter amplitude in Minkowski space. The form factor expressed through the Euclidean Bethe-Salpeter amplitude (both within and without static approximation) considerably differs from the Minkowski one, whereas form factor found in the light-front approach is almost indistinguishable from it.Comment: 3 pages, 2 figures. Contribution to the proceedings of the 20th International Conference on Few-Body Problems in Physics (FB20), Pisa, Italy, September 10-14, 2007. To be published in "Few-Body Systems

    HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.

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    Most studies of HIV latency focus on the peripheral population of resting memory T cells, but the brain also contains a distinct reservoir of HIV-infected cells in microglia, perivascular macrophages, and astrocytes. Studying HIV in the brain has been challenging, since live cells are difficult to recover from autopsy samples and primate models of SIV infection utilize viruses that are more myeloid-tropic than HIV due to the expression of Vpx. Development of a realistic small animal model would greatly advance studies of this important reservoir and permit definitive studies of HIV latency. When radiation or busulfan-conditioned, immune-deficient NSG mice are transplanted with human hematopoietic stem cells, human cells from the bone marrow enter the brain and differentiate to express microglia-specific markers. After infection with replication competent HIV, virus was detected in these bone marrow-derived human microglia. Studies of HIV latency in this model would be greatly enhanced by the development of compounds that can selectively reverse HIV latency in microglial cells. Our studies have identified members of the CoREST repression complex as key regulators of HIV latency in microglia in both rat and human microglial cell lines. The monoamine oxidase (MAO) and potential CoREST inhibitor, phenelzine, which is brain penetrant, was able to stimulate HIV production in human microglial cell lines and human glial cells recovered from the brains of HIV-infected humanized mice. The humanized mice we have developed therefore show great promise as a model system for the development of strategies aimed at defining and reducing the CNS reservoir

    Bethe-Salpeter equation for doubly heavy baryons in the covariant instantaneous approximation

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    In the heavy quark limit, a doubly heavy baryon is regarded as composed of a heavy diquark and a light quark. We establish the Bethe-Salpeter (BS) equations for the heavy diquarks and the doubly heavy baryons, respectively, to leading order in a 1/mQ1/m_{Q} expansion. The BS equations are solved numerically under the covariant instantaneous approximation with the kernels containing scalar confinement and one-gluon-exchange terms. The masses for the heavy diquarks and the doubly heavy baryons are obtained and the non-leptonic decay widths for the doubly heavy baryons emitting a pseudo-scalar meson are calculated within the model.Comment: Corrections to the text, two references added, version accepted for publication in Physical Review

    In memoriam of AndrĂ©s PĂ©rez-EstaĂșn

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    A new vibrational level of the H2+_2^+ molecular ion

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    A new state of the H2+_2^+ molecular ion with binding energy of 1.09×10−9\times10^{-9} a.u. below the first dissociation limit is predicted, using highly accurate numerical nonrelativistic quantum calculations. It is the first L=0 excited state, antisymmetric with respect to the exchange of the two protons. It manifests itself as a huge p-H scattering length of a=750±5a=750\pm 5 Bohr radii.Comment: 6 pages + 3 figure

    Manifestation of three-body forces in three-body Bethe-Salpeter and light-front equations

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    Bethe-Salpeter and light-front bound state equations for three scalar particles interacting by scalar exchange-bosons are solved in ladder truncation. In contrast to two-body systems, the three-body binding energies obtained in these two approaches differ significantly from each other: the ladder kernel in light-front dynamics underbinds by approximately a factor of two compared to the ladder Bethe-Salpeter equation. By taking into account three-body forces in the light-front approach, generated by two exchange-bosons in flight, we find that most of this difference disappears; for small exchange masses, the obtained binding energies coincide with each other.Comment: 24 pages, 8 figures, submitted in Few-Body System

    Antiproton-Hydrogen annihilation at sub-kelvin temperatures

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    The main properties of the interaction of ultra low-energy antiprotons (E≀10−6% E\le10^{-6} a.u.) with atomic hydrogen are established. They include the elastic and inelastic cross sections and Protonium (Pn) formation spectrum. The inverse Auger process (Pn+e→H+pˉPn+e \to H+\bar{p}) is taken into account in the framework of an unitary coupled-channels model. The annihilation cross-section is found to be several times smaller than the predictions made by the black sphere absorption models. A family of pˉH\bar{p}H nearthreshold metastable states is predicited. The dependence of Protonium formation probability on the position of such nearthreshold S-matrix singularities is analysed. An estimation for the HHˉH\bar{H} annihilation cross section is obtained.Comment: latex.tar.gz file, 22 pages, 9 figure
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