15,890 research outputs found
Embryo impacts and gas giant mergers II: Diversity of Hot Jupiters' internal structure
We consider the origin of compact, short-period, Jupiter-mass planets. We
propose that their diverse structure is caused by giant impacts of embryos and
super-Earths or mergers with other gas giants during the formation and
evolution of these hot Jupiters. Through a series of numerical simulations, we
show that typical head-on collisions generally lead to total coalescence of
impinging gas giants. Although extremely energetic collisions can disintegrate
the envelope of gas giants, these events seldom occur. During oblique and
moderately energetic collisions, the merger products retain higher fraction of
the colliders' cores than their envelopes. They can also deposit considerable
amount of spin angular momentum to the gas giants and desynchronize their spins
from their orbital mean motion. We find that the oblateness of gas giants can
be used to infer the impact history. Subsequent dissipation of stellar tide
inside the planets' envelope can lead to runaway inflation and potentially a
substantial loss of gas through Roche-lobe overflow. The impact of super-Earths
on parabolic orbits can also enlarge gas giant planets' envelope and elevates
their tidal dissipation rate over 100 Myr time scale. Since giant
impacts occur stochastically with a range of impactor sizes and energies, their
diverse outcomes may account for the dispersion in the mass-radius relationship
of hot Jupiters.Comment: 19 pages, 7 figures, 7 tables. Accepted for publication in MNRA
Case-control study of arsenic in drinking water and lung cancer in California and Nevada.
Millions of people are exposed to arsenic in drinking water, which at high concentrations is known to cause lung cancer in humans. At lower concentrations, the risks are unknown. We enrolled 196 lung cancer cases and 359 controls matched on age and gender from western Nevada and Kings County, California in 2002-2005. After adjusting for age, sex, education, smoking and occupational exposures, odds ratios for arsenic concentrations ≥85 µg/L (median = 110 µg/L, mean = 173 µg/L, maximum = 1,460 µg/L) more than 40 years before enrollment were 1.39 (95% CI = 0.55-3.53) in all subjects and 1.61 (95% CI = 0.59-4.38) in smokers. Although odds ratios were greater than 1.0, these increases may have been due to chance given the small number of subjects exposed more than 40 years before enrollment. This study, designed before research in Chile suggested arsenic-related cancer latencies of 40 years or more, illustrates the enormous sample sizes needed to identify arsenic-related health effects in low-exposure countries with mobile populations like the U.S. Nonetheless, our findings suggest that concentrations near 100 µg/L are not associated with markedly high relative risks
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Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies.
Studies indicate that the gut microbiota (GM) can significantly influence both local and systemic host physiologic processes. With rising concern for optimization of experimental reproducibility and translatability, it is essential to consider the GM in study design. However, GM profiles can vary between rodent producers making consistency between models challenging. To circumvent this, we developed outbred CD1 mouse colonies with stable, complex GM profiles that can be used as donors for a variety of GM transfer techniques including rederivation, co-housing, cross-foster, and fecal microbiota transfer (FMT). CD1 embryos were surgically transferred into CD1 or C57BL/6 surrogate dams that varied by GM composition and complexity to establish four separate mouse colonies harboring GM profiles representative of contemporary mouse producers. Using targeted 16S rRNA amplicon sequencing, subsequent female offspring were found to have similar GM profiles to surrogate dams. Furthermore, breeding colonies of CD1 mice with distinct GM profiles were maintained for nine generations, demonstrating GM stability within these colonies. To confirm GM stability, we shipped cohorts of these four colonies to collaborating institutions and found no significant variation in GM composition. These mice are an invaluable experimental resource that can be used to investigate GM effects on mouse model phenotype
Detection of Single Ion Spectra by Coulomb Crystal Heating
The coupled motion of ions in a radiofrequency trap has been used to connect
the frequency- dependent laser-induced heating of a sympathetically cooled
spectroscopy ion with changes in the fluorescence of a laser-cooled control
ion. This technique, sympathetic heating spectroscopy, is demonstrated using
two isotopes of calcium. In the experiment, a few scattered photons from the
spectroscopy ion are transformed into a large deviation from the steady-state
fluorescence of the control ion. This allows us to detect an optical transition
where the number of scattered photons is below our fluorescence detection
limit. Possible applications of the technique to molecular ion spectroscopy are
briefly discussed.Comment: 7 Pages,10 Figure
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