Recent developments in genetics and medically assisted reproduction : from research to clinical applications

Two leading European professional societies, the European Society of Human Genetics and the European Society for Human Reproduction and Embryology, have worked together since 2004 to evaluate the impact of fast research advances at the interface of assisted reproduction and genetics, including their application into clinical practice. In September 2016, the expert panel met for the third time. The topics discussed highlighted important issues covering the impacts of expanded carrier screening, direct-to-consumer genetic testing, voiding of the presumed anonymity of gamete donors by advanced genetic testing, advances in the research of genetic causes underlying male and female infertility, utilisation of massively parallel sequencing in preimplantation genetic testing and non-invasive prenatal screening, mitochondrial replacement in human oocytes, and additionally, issues related to cross-generational epigenetic inheritance following IVF and germline genome editing. The resulting paper represents a consensus of both professional societies involved.Peer reviewe

Economic and social transformation through fish farming: A CSR initiative in Bharatpur district, Rajasthan

Not AvailableThe innovative corporate social responsibility (CSR) initiative of Lupin Human Welfare and Research Foundation, Bharatpur, Rajasthan, India, through fish farming in Kaman Block of Bharatpur has transformed the lives of the local population. Fish farming started with 240 families in 1980, is now benefiting 2000 people and has brought economic and social transformation in this region. Cost-benefit analysis indicated that fish farmers culturing Indian major carps (IMC) for 18 months from spawn to table size registered a benefit-cost ratio (BCR) of 2.15. The fish farmers who cultured IMC for 12 months (from fingerlings to table size ) achieved a BCR of 1.77. The results of data envelopment analysis (DEA) showed that the technical efficiency was around 0.95, indicating highly efficient farms. Polluted water, disruption in power supply and poaching were found to be major constraints faced by the farmers.Not Availabl