Investigating the level of moral distress and its related factors among nurses in mazandaran burn center

Background and purpose: Moral distress is a common phenomenon in nursing professional and burn nurses are constantly faced with making different moral decisions for patients who are in terrible conditions. Therefore, nurses in burn units experience moral distress as mental tension. This study was conducted to determine the severity of moral distress and the factors associated with that in burn nurses. Materials and methods: A descriptive- analytical study was conducted using census sampling on 172 nurses working in Mazandaran burn center, 2014. Data was collected through identifying demographic and occupational characteristics of the nurses (using relevant questionnaires) and Corley’s Moral Distress Scale. Data analysis was performed applying Mann-Whitney and Kruskal-Wallis test. Results: The mean score for moral distress was 105.65±52.39 which indicates a moderate level experienced by nurses. Kruskal-Wallis test showed a significant positive correlation between educational level and level of moral distress (P=0.011). There was no significant association between moral distress and other individual and professional characteristics (P>0.05). Conclusion: Moral distress is accompanied by many complications that have direct effects on nurses’ professional practice. Therefore, nurse managers should consider this issue and plan for programs on appropriate coping strategies. © 2015, Mazandaran University of Medical Sciences. All rights reserved

Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia.

BACKGROUND: Tudor domain-containing proteins (TDRDs) play a critical role in piRNA biogenesis and germ cell development. piRNAs, small regulatory RNAs, act by silencing of transposons during germline development and it has recently been shown in animal model studies that defects in TDRD genes can lead to sterility in males. METHODS: Here we evaluate gene and protein expression levels of four key TDRDs (TDRD1, TDRD5, TDRD9 and TDRD12) in testicular biopsy samples obtained from men with obstructive azoospermia (OA, n = 29), as controls, and various types of non-obstructive azoospermia containing hypospermatogenesis (HP, 28), maturation arrest (MA, n = 30), and Sertoli cell-only syndrome (SCOS, n = 32) as cases. One-way ANOVA test followed by Dunnett's multiple comparison post-test was used to determine inter-group differences in TDRD gene expression among cases and controls. RESULTS: The results showed very low expression of TDRD genes in SCOS specimens. Also, the expression of TDRD1 and TDRD9 genes were lower in MA samples compared to OA samples. The expression of TDRD5 significantly reduced in SCOS, MA and HP specimens than the OA specimens. Indeed, TDRD12 exhibited a very low expression in HP specimens in comparison to OA specimens. All these results were confirmed by Western blot technique. CONCLUSION: TDRDs could be very important in male infertility, which should be express in certain stages of spermatogenesis

Multi-objective optimisation method for coordinating battery storage systems, photovoltaic inverters and tap changers

The many well-established advantages of distributed generation (DG) make their usage in active distribution networks prevalent. However, uncontrolled operation of DG units can negatively interfere with the performance of other equipment, such as tap-changers, in addition to resulting in sub-optimal usage of their potential. Thus, adequate scheduling/control of DG units is critical for operators of the distribution system to avoid those adverse effects. A linearised model of a multi-objective method for coordinating the operation of photovoltaics, battery storage systems, and tap-changers is proposed. Three objective functions are defined for simultaneously enhancing voltage profile, minimising power losses, and reducing peak load power. The formulated multi-objective problem is solved by means of the epsilon-constraint technique. A novel decision-making methodology is offered to find the Pareto optimality and select the preferred solution. To assess to proposed model's performance, it is tested using 33-bus IEEE test system. Consequently, tap-changers suffer lessened stress, the batteries state-of-charge is kept within adequate limits, and the DG units operation is at higher efficiency. The obtained results verify the effectiveness of this approach.fi=vertaisarvioitu|en=peerReviewed

Postoperative Blepharoptosis After Modern Phacoemulsification Procedure

Purpose: To investigate the frequency of transient (1 month) and persistent (at least 6 months) postoperative ptosis following clear corneal sutureless phacoemulsification and to analyze the factors affecting them. Design: Cohort study. Methods: Patients who underwent phacoemulsification cataract surgery from October 2016 to June 2018 in a tertiary center were enrolled. Margin reflex distance 1 (MRD1), MRD2, and levator function were measured and facial photography was taken before, 1 month, and at least 6 months after the surgery. Clinical ptosis was defined as any postoperative drop of MRD1 and clinically significant ptosis as MRD1 drop of �2 mm. Photo-based ptosis was assessed by a masked oculofacial plastic surgeon at the end of the study. Results: A total of 234 patients (313 eyelids) were included. The majority of surgeries were performed by senior residents (65.5, 205/313) and under topical anesthesia (78.0, 244/313). Persistent clinical, clinically significant, and photo-based ptosis were 25.4 (71/279), 3.2 (9/279), and 3.3 (9/276). Eyelids with persistent postoperative ptosis showed a significantly (P = .03) lower preoperative levator function (13.9 vs 15.8 mm). No other factor was significantly different between the eyelids with and without postoperative ptosis. Conclusion: Persistent clinically significant ptosis was observed in more than 3 of patients undergoing clear corneal sutureless phacoemulsification cataract surgery. It should be counseled preoperatively. Lower preoperative levator function was significantly associated with a higher frequency of postoperative ptosis. Duration of surgery, level of surgeons, and other variables did not have any significant effect on the frequency of postoperative ptosis. © 2020 Elsevier Inc

Tilapia culture in aquaponic system

Iran is one of ten disaster countries in terms of water crisis. Also, deficit of agricultural soil is a limiting agent for development of agronomy. Moreover, production of organic crops is very important for health nutrition. Tilapia is an important commercial fish because of its fast growth, tolerance to environmental conditions and diseases, possibility of intensive culture, low costs of production and marketable flavor. Production of aquatic and agricultural crops in an aquaponic system would ask these expectations. Aquaponic system that includes combination of hydroponics and water recycling systems was examined for modulated culture of tilapia and agricultural crops at the present study. Tilapia fries with 6.2g and 5.9g mean weight and stocking density of 40/m^3 were respectively stocked in two 2.5m^3 tanks at September 2013 for 9 months. Fish culture in the two tanks tended to 17.2kg/m^3 and 19kg/m^3 fish production with 658g and 596 mean final weigth, 98% and 100% survival and 1.4 and 1.6 food conversion rate (FCR), respectively. Plants were implanted using grow beds, floating rafts and nutrient film methods. Monthly production of mint, basil, lettuce, cucumber, tomato, pepper were 1.14, 0.5-0.8, 1.32, 2.7-4, 2.03-3.4 and 1.1 kg/m^2 crops, respectively

DMD: A Large-Scale Multi-Modal Driver Monitoring Dataset for Attention and Alertness Analysis

Vision is the richest and most cost-effective technology for Driver Monitoring Systems (DMS), especially after the recent success of Deep Learning (DL) methods. The lack of sufficiently large and comprehensive datasets is currently a bottleneck for the progress of DMS development, crucial for the transition of automated driving from SAE Level-2 to SAE Level-3. In this paper, we introduce the Driver Monitoring Dataset (DMD), an extensive dataset which includes real and simulated driving scenarios: distraction, gaze allocation, drowsiness, hands-wheel interaction and context data, in 41 hours of RGB, depth and IR videos from 3 cameras capturing face, body and hands of 37 drivers. A comparison with existing similar datasets is included, which shows the DMD is more extensive, diverse, and multi-purpose. The usage of the DMD is illustrated by extracting a subset of it, the dBehaviourMD dataset, containing 13 distraction activities, prepared to be used in DL training processes. Furthermore, we propose a robust and real-time driver behaviour recognition system targeting a real-world application that can run on cost-efficient CPU-only platforms, based on the dBehaviourMD. Its performance is evaluated with different types of fusion strategies, which all reach enhanced accuracy still providing real-time response.Comment: Accepted to ECCV 2020 workshop - Assistive Computer Vision and Robotic

Factors associated with TBS worse than BMD in non-osteoporotic elderly population: Bushehr elderly health program

Background: Bone mineral density (BMD) and trabecular bone score (TBS) are moderately correlated. TBS is sometimes used as an adjuvant to BMD in the fracture risk assessment. Some individuals with normal BMD or osteopenia, have more degraded TBS. We aimed to identify factors associated with TBS worse than BMD in the non-osteoporotic elderly population. Methods: The study subjects were selected from 2384 women and men aged ≥60 years participating in the second stage of the Bushehr Elderly Health program, a population-based prospective cohort study in Iran. The BMDs of different sites and the lumbar spine texture were measured using dual-energy X-ray absorptiometry and the TBS algorithm, respectively. Subjects were categorized based on their BMD and TBS status

The association between HPV gene expression, inflammatory agents and cellular genes involved in EMT in lung cancer tissue

BACKGROUND: Lung cancer is a leading cause of cancer morbidity and mortality worldwide. Several studies have suggested that Human papillomavirus (HPV) infection is an important risk factor in the development of lung cancer. In this study, we aim to address the role of HPV in the development of lung cancer mechanistically by examining the induction of inflammation and epithelial-mesenchymal transition (EMT) by this virus. METHODS: In this case-control study, tissue samples were collected from 102 cases with lung cancer and 48 controls. We examined the presence of HPV DNA and also the viral genotype in positive samples. We also examined the expression of viral genes (E2, E6 and E7), anti-carcinogenic genes (p53, retinoblastoma (RB)), and inflammatory cytokines in HPV positive cases. RESULTS: HPV DNA was detected in 52.9 (54/102) of the case samples and in 25 (12/48) of controls. A significant association was observed between a HPV positive status and lung cancer (OR�=�3.37, 95 C.I�=�1.58-7.22, P�=�0.001). The most prevalent virus genotype in the patients was type 16 (38.8). The expression of p53 and RB were decreased while and inflammatory cytokines were increased in HPV-positive lung cancer and HPV-positive control tissues compared to HPV-negative lung cancer and HPV-negative control tissues. Also, the expression level of E-cad and PTPN-13 genes were decreased in HPV- positive samples while the expression level of SLUG, TWIST and N-cad was increased in HPV-positive samples compared to negative samples. CONCLUSION: Our study suggests that HPV infection drives the induction of inflammation and EMT which may promote in the development of lung cancer

Original article title: "Comparison of therapeutic efficacy of topical corticosteroid and oral zinc sulfate-topical corticosteroid combination in the treatment of vitiligo patients: a clinical trial"

<p>Abstract</p> <p>Background</p> <p>Vitiligo is the most prevalent pigmentary disorder which occurs worldwide, with an incidence rate between 0.1-4 percent. It is anticipated that the discovery of biological pathways of vitiligo pathogenesis will provide novel therapeutic and prophylactic targets for future approaches to the treatment and prevention of vitiligo. The purposes of this study were evaluating the efficacy of supplemental zinc on the treatment of vitiligo.</p> <p>Methods</p> <p>This randomized clinical trial was conducted for a period of one year. Thirty five patients among 86 participants were eligible to entrance to the study. The patients in two equal randomized groups took topical corticosteroid and combination of oral zinc sulfate-topical corticosteroid.</p> <p>Results</p> <p>The mean of responses in the corticosteroid group and the zinc sulfate-corticosteroid combination group were 21.43% and 24.7%, respectively.</p> <p>Conclusion</p> <p>Although, the response to corticosteroid plus zinc sulfate was more than corticosteroid, there was no statistically significant difference between them. It appeared that more robust long-term randomized controlled trials on more patients, maybe with higher doses of zinc sulfate, are needed to fully establish the efficacy of oral zinc in management of vitiligo.</p> <p>Trial Registration</p> <p>chiCTRTRC10000930</p