1,174 research outputs found

    Isolation, Identification and Seasonal Distribution of Soilborne Fungi in Different Areas of Erbil Governorate

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    A survey study was undertaken for the isolation and identification of soilborne fungi inhabiting different areas in Erbil, Iraq. A total of 15 soil samples collected seasonally during August 2008-July 2009. Fungi were isolated from soil during this study\u27s period, by soil dilution plate method on selective medium: Potato Dextrose Agar (PDA), eighty-one different genera of fungi were isolated during the four seasons; (30, 33, 70, and 53) genera isolated in (summer, autumn, winter and spring) respectively, the most frequently isolated fungi during four seasons were Aspergillus sp. (539x103) colony forming units /g.soil, followed by Penicillium sp. (215x103) cfu/g.soil, Rhizopus spp. (115x103) cfu/g.soil, Emericella spp. (109x103) cfu/g.soil, Fusarium spp. (47x103) cfu/g.soil, and Ulocladium botrytis (47x103) cfu/g.soil, while the least frequently isolated fungal genera were Blakeslea tuningtam, Clasterosporium cyperi, Idriella sp., Naranus cryptomeriae and Torula alternata, (1x103) cfu/g.soil, for each one. Fungi isolated from soil by washing method counted for ninety three species belonging to fifty six genera, among them: Aspergillus sp., Circinella sp., Cunninghamella sp., Mucor spp., Mycelia sterilia, Rhizopus sp

    Design and assessment of biodegradable macroporous cryogels as advanced tissue engineering and drug carrying materials

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    Cryogels obtained by the cryotropic gelation process are macroporous hydrogels with a well-developed system of interconnected pores and shape memory. There have been significant recent advancements in our understanding of the cryotropic gelation process, and in the relationship between components, their structure and the application of the cryogels obtained. As cryogels are one of the most promising hydrogel-based biomaterials, and this field has been advancing rapidly, this review focuses on the design of biodegradable cryogels as advanced biomaterials for drug delivery and tissue engineering. The selection of a biodegradable polymer is key to the development of modern biomaterials that mimic the biological environment and the properties of artificial tissue, and are at the same time capable of being safely degraded/metabolized without any side effects. The range of biodegradable polymers utilized for cryogel formation is overviewed, including biopolymers, synthetic polymers, polymer blends, and composites. The paper discusses a cryotropic gelation method as a tool for synthesis of hydrogel materials with large, interconnected pores and mechanical, physical, chemical and biological properties, adapted for targeted biomedical applications. The effect of the composition, cross-linker, freezing conditions, and the nature of the polymer on the morphology, mechanical properties and biodegradation of cryogels is discussed. The biodegradation of cryogels and its dependence on their production and composition is overviewed. Selected representative biomedical applications demonstrate how cryogel-based materials have been used in drug delivery, tissue engineering, regenerative medicine, cancer research, and sensing

    Hybrid Method for Digits Recognition using Fixed-Frame Scores and Derived Pitch

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    This paper presents a procedure of frame normalization based on the traditional dynamic time warping (DTW) using the LPC coefficients. The redefined method is called as the DTW frame-fixing method (DTW-FF), it works by normalizing the word frames of the input against the reference frames. The enthusiasm to this study is due to neural network limitation that entails a fix number of input nodes for when processing multiple inputs in parallel. Due to this problem, this research is initiated to reduce the amount of computation and complexity in a neural network by reducing the number of inputs into the network. In this study, dynamic warping process is used, in which local distance scores of the warping path are fixed and collected so that their scores are of equal number of frames. Also studied in this paper is the consideration of pitch as a contributing feature to the speech recognition. Results showed a good performance and improvement when using pitch along with DTW-FF feature. The convergence rate between using the steepest gradient descent is also compared to another method namely conjugate gradient method. Convergence rate is also improved when conjugate gradient method is introduced in the back-propagation algorithm

    Bounded Solutions of Certain (Differential and first order systems of Differential Equations)

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    In this paper we prove the of solutions, of some kinds of differential equations, and system of first order differential equations are bounded. Key words: Boundedness of solutions, first order ordinary Ā Differential equations, systems of differential equations and limit cycles

    An elective combined caesarean section and small bowel GIST resection during the third trimester of pregnancy: Report of a case

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    AbstractINTRODUCTIONGastro-Intestinal Stromal Tumours (GISTs) are rare with an estimated incidence of only 11ā€“15 per million. In pregnancy, GISTs are an extremely rare occurrence and are thus complex to manage from an ethical, surgical and oncological perspective.PRESENTATION OF CASEWe present the first reported case in the literature of a successful combined lower segment caesarean section (LSCS) and a tumour resection in a 31-year-old pregnant patient presenting with a small bowel GIST.DISCUSSIONWe compare and contrast our case with other reported cases of GIST resection in pregnancy and discuss the challenges faced by both patients and clinicians.CONCLUSIONOur case demonstrates that a combined LSCS and GIST resection is feasible. In addition, our case highlights the importance of both the multidisciplinary setting and the consideration of patientsā€™ wishes in the successful management of this complex group of patients

    Benevolent Agents

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    Some agents roaming the Web these days are benevolent-for example, they may clean up stalled or failed database transactions, or share query results that may have cost substantial resources to acquire and might consume more to share. The Agent Behavior Testbed is a tool for studying the economics of agent altruism. As more agents hit the Internet, benevolence and cooperation will help with overall efficiency and productivity. The paper discusses benevolent agents on the Web

    On Automated Lemma Generation for Separation Logic with Inductive Definitions

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    Separation Logic with inductive definitions is a well-known approach for deductive verification of programs that manipulate dynamic data structures. Deciding verification conditions in this context is usually based on user-provided lemmas relating the inductive definitions. We propose a novel approach for generating these lemmas automatically which is based on simple syntactic criteria and deterministic strategies for applying them. Our approach focuses on iterative programs, although it can be applied to recursive programs as well, and specifications that describe not only the shape of the data structures, but also their content or their size. Empirically, we find that our approach is powerful enough to deal with sophisticated benchmarks, e.g., iterative procedures for searching, inserting, or deleting elements in sorted lists, binary search tress, red-black trees, and AVL trees, in a very efficient way

    Regularity of Infinity for Elliptic Equations with Measurable Coefficients and Its Consequences

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    This paper introduces a notion of regularity (or irregularity) of the point at infinity for the unbounded open subset of \rr^{N} concerning second order uniformly elliptic equations with bounded and measurable coefficients, according as whether the A-harmonic measure of the point at infinity is zero (or positive). A necessary and sufficient condition for the existence of a unique bounded solution to the Dirichlet problem in an arbitrary open set of \rr^{N}, N\ge 3 is established in terms of the Wiener test for the regularity of the point at infinity. It coincides with the Wiener test for the regularity of the point at infinity in the case of Laplace equation. From the topological point of view, the Wiener test at infinity presents thinness criteria of sets near infinity in fine topology. Precisely, the open set is a deleted neigborhood of the point at infinity in fine topology if and only if infinity is irregular.Comment: 20 page

    Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data.

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    BACKGROUND: The efficacy of RTS,S/AS01 as a vaccine for malaria is being tested in a phase 3 clinical trial. Early results show significant, albeit partial, protection against clinical malaria and severe malaria. To ascertain variations in vaccine efficacy according to covariates such as transmission intensity, choice of adjuvant, age at vaccination, and bednet use, we did an individual-participant pooled analysis of phase 2 clinical data. METHODS: We analysed data from 11 different sites in Africa, including 4453 participants. We measured heterogeneity in vaccine efficacy by estimating the interactions between covariates and vaccination in pooled multivariable Cox regression and Poisson regression analyses. Endpoints for measurement of vaccine efficacy were infection, clinical malaria, severe malaria, and death. We defined transmission intensity levels according to the estimated local parasite prevalence in children aged 2-10 years (PrPā‚‚ā‚‹ā‚ā‚€), ranging from 5% to 80%. Choice of adjuvant was either AS01 or AS02. FINDINGS: Vaccine efficacy against all episodes of clinical malaria varied by transmission intensity (p=0Ā·001). At low transmission (PrPā‚‚ā‚‹ā‚ā‚€ 10%) vaccine efficacy was 60% (95% CI 54 to 67), at moderate transmission (PrPā‚‚ā‚‹ā‚ā‚€ 20%) it was 41% (21 to 57), and at high transmission (PrPā‚‚ā‚‹ā‚ā‚€ 70%) the efficacy was 4% (-10 to 22). Vaccine efficacy also varied by adjuvant choice (p<0Ā·0001)--eg, at low transmission (PrPā‚‚ā‚‹ā‚ā‚€ 10%), efficacy varied from 60% (95% CI 54 to 67) for AS01 to 47% (14 to 75) for AS02. Variations in efficacy by age at vaccination were of borderline significance (p=0Ā·038), and bednet use and sex were not significant covariates. Vaccine efficacy (pooled across adjuvant choice and transmission intensity) varied significantly (p<0Ā·0001) according to time since vaccination, from 36% efficacy (95% CI 24 to 45) at time of vaccination to 0% (-38 to 38) after 3 years. INTERPRETATION: Vaccine efficacy against clinical disease was of limited duration and was not detectable 3 years after vaccination. Furthermore, efficacy fell with increasing transmission intensity. Outcomes after vaccination cannot be gauged accurately on the basis of one pooled efficacy figure. However, predictions of public-health outcomes of vaccination will need to take account of variations in efficacy by transmission intensity and by time since vaccination. FUNDING: Medical Research Council (UK); Bill & Melinda Gates Foundation Vaccine Modelling Initiative; Wellcome Trust
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