398 research outputs found
Acute dystonia by droperidol during intravenous patient-controlled analgesia in young patients.
Patient-controlled analgesia (PCA) is an important means for postoperative analgesia with parenteral opioid. However, postoperative nausea and vomiting (PONV) remains a major problem with a PCA system. Droperidol is used in PCA to prevent PONV. Extrapyramidal reactions by droperidol are, however, occasionally induced. We describe two cases of severe extrapyramidal hypertonic syndrome with an intravenous administration of droperidol in PCA in young patients, following orthopedic surgery
In vitro selection of salt-tolerant Ailanthus altissimaSwingle
Salt-tolerant cell lines of Ailanthus altissima were selected from callus derived protoplasts. Murashige–Skoog (MS) liquid medium incorporated with various concentrations of NaCl was employed to enrich salt-tolerant A. altissima cell lines. Salt-resistant A. altissima cells were transferred on MS solid medium supplemented with 2.5 μM 2,4-dichlorophenoxy acetic acid (2,4-D), 0.5 μM benzyl adenine (BA) and various NaCl concentrations. The callus was cultured on MS medium containing NaCl for 5 months, to determine the survival rate as an index of salt tolerance. The measurement of growth parameters for salt-tolerant cells showed that the selected plant cell lines grew better than the unselected ones at all levels of NaCl tested. The salt-tolerant callus accumulated proline in correlation to the concentration of salts. Media supplemented with BA induced shoot differentiation of salt-resistant A. altissima cells
Effect of pectoralis major myofascial release massage for breastfeeding mothers on breast pain, engorgement, and newborns’ breast milk intake and sleeping patterns in Korea: a randomized controlled trial
Purpose Supportive interventions to improve breastfeeding practice are needed in nursing. This study investigated the effects of pectoralis major myofascial release massage (MRM) on breast pain and engorgement among breastfeeding mothers and on breast milk intake and sleep patterns among newborns. Methods Breastfeeding mothers who had delivered between 37 and 43 weeks and had 7- to 14-day-old newborns were recruited from a postpartum care center in Gunpo, Korea. Participants were randomized to the MRM or control group. The outcome variables were breast pain and breast engorgement among breastfeeding mothers and breast milk intake and sleep time among newborns. The experimental treatment involved applying MRM to separate the pectoralis major muscle and the underlying breast tissue in the chest. After delivery, the first MRM session (MRM I) was provided by a breast specialist nurse, and the second (MRM II) was administered 48 hours after MRM I. Results Following MRM, breast pain (MRM I: t=−5.38, p<.001; MRM II: t=−10.05, p<.001), breast engorgement (MRM I: right, t=−1.68, p=.100; left, t=−2.13, p=.037 and MRM II: right, t=−4.50, p<.001; left, t=−3.74, p<.001), and newborn breast milk intake (MRM I: t=3.10, p=.003; MRM II: t=3.09, p=.003) differed significantly between the groups. Conclusion MRM effectively reduced breast engorgement and breast pain in breastfeeding mothers, reducing the need for formula supplementation, and increasing newborns’ breast milk intake. Therefore, MRM can be utilized as an effective nursing intervention to alleviate discomfort during breastfeeding and to improve the rate of breastfeeding practice (clinical trial number: KCT0002436)
Corrigendum: Effect of pectoralis major myofascial release massage for breastfeeding mothers on breast pain, engorgement, and newborns’ breast milk intake and sleeping patterns in Korea: a randomized controlled trial
The Pathogenetic Role of Reactive Oxygen Species in Aminonucleoside Nephrosis
We studied the pathogenetic role of reactive oxygen species (ROS) in
rats with puromycin aminonucleoside nephrosis (PAN). Heavy albuminuria with markedly
decreased density of the anionic sites (AS) on glomerular basement membrane
(GBM) (2. 6 ± O. 98 compared to 20. 0 ± 1. 61 AS/l,OOOnm GBM in control) developed
7 days after PA injection. The malondialdehyde (MDA) levels in kidney
homogenates increased gradually (1. 16 ± O. 18 at day -1 to 1. 97 ± O. 23/g protein
at day 5). While catalase or dimethyl sulfoxide, administered with PA, did not affect the
course of PAN. superoxide dismutase and allopurinol reduced proteinuria
and decreased loss of the AS (11. 7 ± 2. 80 and 13, 7 ± 1. 27 AS/l.000nm GBM, reo
spectively) at day 7. These findings suggest that proteinuria in PAN results from the
loss of GBM AS. in which ROS generated by xanthine oxidase system plays an import.
ant role
Selection of high berberine yielding phellodendron insulare nak. lines and the antimicrobial activity of their extracts
High berberine yielding Phellodendron insulare Nak. lines were selected by aggregate cloning method and the antimicrobial activity of their extracts was assessed. The berberine producing cork tree lines were selected by adopting a colorimetric method. In all 300 high berberine producing lines were selected with a colorimetric reagent containing 5M HCl and H2O2 and established from dissociated cell aggregates. The crude extracts from these lines showed antibacterial activities against tested Escherichia coli, Staphylococcus aureus, Salmonella typhimulium, and Listeria monocytogenes. The cork tree extracts were found to be inhibitory to these test organisms. Further the antimicrobial activity of plant extracts was on par with the berberine isolated from the extracts from native cork trees. These results have potential for developing alternative plant products as antimicrobial substances for application in agriculture and food industry
A Rare Case of Recurrent Myoid Hamartoma Mimicking Malignancy: Imaging Appearances
Myoid hamartoma is an uncommon type of breast hamartoma and its recurrence is very rare. We report the imaging appearance of an unusual case of recurrent myoid hamartoma of the breast mimicking malignancy in a 43-year-old woman. Although the mammographic and ultrasonographic findings have long been described in the literature, MR finding with a dynamic study has not, to the best of our knowledge, been reported previously
Factors Associated with HIV-1 Proviral DNA Loads in Patients with Undetectable Plasma RNA Load
To evaluate factors associated with human immunodeficiency virus type 1 (HIV-1) proviral DNA load, we conducted a cross-sectional study of 36 chronically HIV-1-infected individuals with undetectable plasma viral RNA. We used real-time polymerase chain reaction to determine the number of HIV-1 proviral DNA copies per 106 peripheral blood mononuclear cells. The mean level of plasma viral RNA when the CD4+ T cell count was above 500 cells/µL without highly active antiretroviral therapy (HAART) was significantly associated with proviral DNA load at the time of undetectable plasma HIV RNA with HAART. Strategies to reduce the level of plasma viral RNA when patients' CD4+ T cell counts are above 500 cells/µL without HAART could help reduce HIV-1 proviral DNA load
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