Abstrak. Penelitian ini Bertujuan untuk Mendeskripsikan Bentuk-bentuk Penyimpangan Prinsip Kerja Sama dan Prinsip Kesantunan dalam Kumpulan Seri Komedi Kamil Onte Pon TV. Metode Penelitian ini Adalah Metode Deskriptif dengan Bentuk Penelitian Bersifat Kua

. Therefore, the research is also aimed to describe the forms of violation in cooperative and politeness principles used in the collection of comedy series Kamil Onte Pon Tv. The method of research uses descriptive method in the form of qualitative research. The sources of research data are collection of comedy series Kamil Onte on Pon Tv consisted of 13 comedy videos, there are Sukep's friend, Mama ask for phone's credit, Mamang doesn't care, Sukep'revenge, Obsession to be Star, Let's go to Kapuas's Main Square, Sukep's story at School, Saturday Night, Kapuas River Water Condition in Pontianak, Fuel oil increases: Sukep takes it easy, Durian's season, Sukep's holiday, and How difficult to be actor. According to the result of data analysis, the researcher found that there are 34 data of the violation of cooperative principle in the collection of comedy series Kamil Onte on Pon Tv. The researcher found 18 data that commit the violation of politeness principle in the collection of comedy series Kamil Onte Pon Tv

Dust attenuation in galaxies at cosmic dawn from the FirstLight simulations

We study the behavior of dust in galaxies at cosmic dawn, z=6-8, by coupling the FirstLight simulations with the radiative transfer code POLARIS. The starburst nature of these galaxies and their complex distribution of dust lead to a large diversity of attenuation curves. These follow the Calzetti model only for relatively massive galaxies, Mstars=10^9Msun. Galaxies with lower masses have steeper curves, consistent with the model for the Small Magellanic Cloud (SMC). The ultraviolet and optical slopes of the attenuation curves are closer to the modified Calzetti model, with a slight preference for the power-law model for galaxies with the highest values of attenuation. We have also examined the relation between the slope in the far-ultraviolet, beta_UV , and the infrared excess, IRX. At z=6, it follows the Calzetti model with a shift to slightly lower beta_UV values due to lower metallicities at lower attenuation. The same relation at z=8 shows a shift to higher IRX values due to a stronger CMB radiation at high-z.Comment: 9 pages, 6 figures, accepted at MNRA

Level of clinical evidence presented at the open and closed American Shoulder and Elbow Surgeons annual meeting over 10 years (2005-2014)

© 2016 The Author(s). Background: The American Shoulder and Elbow Surgeons (ASES) annual scientific meetings are premier forums whereby orthopaedic surgeons are informed of the latest research advances in shoulder and elbow surgery. The purpose of the present study was to assess the Level of evidence (LOE) in the clinical papers presented at both the open and closed ASES annual scientific meetings from 2005 to 2014. Secondarily, the study evaluated whether there were any changes in the distribution of LOE over this period of time. Methods: Two reviewers independently evaluated the abstracts of 532 paper presentations at either the open or closed ASES annual meetings. The independent reviewers first screened the abstracts for clinical evidence and excluded cadaveric, biomechanical, technique, and review studies. The included abstracts were then independently graded for methodological quality using LOE from Level I (highest quality) to IV (lowest quality) based on the classification system created by The American Academy of Orthopaedic Surgeons (AAOS). Results: Overall, 421 presentations were included and graded for LOE. In general, 17% of the presentations were graded level I; 15% level II; 25% level III; and 43% assigned a LOE of IV. Chi-square analysis demonstrated a statistically significant improvement in the LOE of presentations at the open and closed ASES meetings combined (p = 0.028) between the years 2005 and 2014. In particular, the proportion of presentations graded as level IV significantly decreased over this period (p = \u3c0.001). Conclusions: While most presentations at the ASES annual scientific meetings were of lower LOEs the percentage of level I evidence is greater than that reported at other Orthopaedic meetings. There has been a significant improvement in the LOE of clinical research at open and closed ASES meetings from 2005 to 2014. Specifically, the proportion of level IV studies have dramatically decreased over time

Radiation pattern reconfigurable fm antenna

In this work, a radiation pattern reconfigurable antenna design using compact printed spiral monopoles that operates at 102 MHz is reported. The proposed antenna changes its radiation behaviour that responds towards a desired direction with the use of RF switches. The antenna is printed on a 76.6mm × 50mm PCB layer providing more than 20MHz bandwidth at -10 dB threshold and is easily fabricated with low manufacturing cost. The antenna was also simulated on 500mm × 500mm ground plane that represents the roof top of a vehicl

Genetic variation between hybrid (Labeo rohita ♂, Cirrhinus mrigala ♀ and Labeo rohita) by RAPD marker

Abstract The present work was to study the genetic variability between the major carps Labeo rohita and Cirrhinus mrigala and their hybrids of L. rohita (male♂) and C. mrigala (female♀). Genetic variability was studied by employing RAPD molecular markers. 25 samples of each target species having different sizes with the same age group for the determination of interspecific variation were collected. The morphometric parameters such as body weight, total length, tail length, and lengths of dorsal and anal fins of each individual were recorded and results showed that wet body weight, total length, dorsal fin, anal fin, and tail fin length are positively correlated and then the DNA was extracted using the inorganic salt-based method and conformed by Gel electrophoresis. Twenty-four arbitrary decamer primers were used to get species-specific RAPD analysis Distinct and highly reproducible RAPD profiles with significant genetic variability was detected among species. Only five primers showed amplification. The RAPAD primer OPB-05 produced a total of seven bands out of these 5 monomorphic and 2 polymorphic, so in this case, the percentage polymorphism was 28.57%. The Hybrid show more than a 50% difference from the Labeo rohita. This shows that the Hybrid more resembles C.mrigala. Phylogenetic analysis demonstrated that hybrid (L. rohita ♂ X Cirrhinus mrigala ♀) is the closest to C. mrigala and the farthest from L. rohita. Overall data are presented concerning the applications of RAPD markers for hybrid identification, genetic diversity assessment, and studying taxonomic relationships at a molecular level

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family

Asymmetric cell division is essential for normal human brain development. Mutations in several genes encoding centrosomal proteins that participate in accurate cell division have been reported to cause autosomal recessive primary microcephaly (MCPH). By homozygosity mapping including three affected individuals from a consanguineous MCPH family from Pakistan, we delineated a critical region of 18.53 Mb on Chromosome 1p21.3-1p13.1. This region contains the gene encoding HsSAS-6, a centrosomal protein primordial for seeding the formation of new centrioles during the cell cycle. Both next-generation and Sanger sequencing revealed a homozygous c.185T>C missense mutation in the HsSAS-6 gene, resulting in a p.Ile62Thr substitution within a highly conserved region of the PISA domain of HsSAS-6. This variant is neither present in any single-nucleotide polymorphism or exome sequencing databases nor in a Pakistani control cohort. Experiments in tissue culture cells revealed that the Ile62Thr mutant of HsSAS-6 is substantially less efficient than the wild-type protein in sustaining centriole formation. Together, our findings demonstrate a dramatic impact of the mutation p.Ile62Thr on HsSAS-6 function and add this component to the list of genes mutated in primary microcephal