Development and Validation of Multi-Modality Instructional Model

Development of models of teaching is the recent innovation in teaching. An important purpose of discussing models of teaching is to assist the teacher to have a wide range of approaches for creating a proper interactive environment for learning. An intelligent use of these approaches enables the teacher to adopt him to the learning needs of the students. A number of educationist and psychologists have proposed model approach to teaching. A model of teaching consists of guidelines for designing educational activities and environments. Model of teaching is a plan that can also be utilized to shape courses of studies, to design instructional material and to guide instruction. Joyce and Weil, (1972) [19] explained Teaching of model is a pattern or plan, which can be a curriculum or courses to select instructional materials and to guide a teachers actions. Educators and psychologist have design several types of teaching models which provides suitable guidelines to the teachers for modifying the behaviour of the learners. As a matter of facts some sorts of models of teaching have been existence since times immemorial. In simple language a models of teaching may be defined as a blueprint designed in advance for providing necessary structure and direction to the teacher for realizing the stipulated objectives. After the investigator completed the determination of the steps the model was presented to the panel of experts. The panel of experts scrutinized and validated the steps of the model and gave their opinion about the fitness of the model for application. They further commented to conduct a pilot study with the application of the model From the pilot try out of the model it was found to be effective for application in classroom teaching. &nbsp

Android Application to Detect and Alert Tachycardia and Bradycardia using Pulse Rate Sensor

Heart rate monitoring is most vital in preventing disorders related to heart. Failure to detect heart disorder in early stage may lead to death. The lacking of devices to immediately detect the abnormalities in heart and alert the patients emergency contact lead to this problem. In this report the author propose a system to detect two heart disorders called Tachycardia and Bradycardia which are caused by abnormalities in heart rate. The proposed system will consist of a pulse sensor which will be connected to a smartphone via Bluetooth. The signal information which is processed by the microcontroller will be sent to the mobile phone. An app created will send an alert to the emergency contacts of the patients when Tachycardia or Bradycardia condition has been detected by the sensor. This will increase the possibilities of giving immediate treatment to the patient, and hope to reduce the death rate caused by heart disorder

Estuarine oceanography of the Vembanad lake Part II : the region between Cochin and Azhikode

Some aspects of the estuarine oceanography of the Vembanad lake between Cochin and Azhikode are discussed. Since this part of the lake is in confluence with the Arabian sea at its southern and northern ends, at Cochin and Azhikode, its circulation pattern and other characteristics are different from what they are between Cochin and Vaikom. Because of the position of these two mouths, which are exposed to the same tidal cycles, the high tides and low tides each producing two opposite flows respectively converge and diverge leaving a null zone, almost free of the tidal effect, around Kadakara, situated midway between Cochin and Azhikode. Another significant feature of this pairt of the estuary is an extreme low-salinity i«gion between Karthedam and Cherai during monsoon and early postmonsoon, brought about by the deflected waiters of the Periyar, opening at the northern end of the estuary

PHYTOCHEMICAL SCREENING, TOXICITY EVALUATION OF POLYCARPAEA CORYMBOSA LAMK AND ITS EFFECT ON CANCER BIOMARKERS OF EHRLICH ASCITES CARCINOMA-INDUCED MICE COMPARED WITH THE REFERENCE STANDARD DRUG 5- FLUOROURACIL

Objective: The current investigation focuses on the study of efficacy of whole plant of Polycarpaea corymbosa Lamk in Ehrlich ascites carcinoma (EAC) inoculated Swiss albino mice. Methods: The whole plant of P. corymbosa Lamk (WPC) was extracted with solvents of increasing polarity and their percentage yields were calculated. The major phytoconstituents present in the plant extracts were determined by standard chemical tests. Tumor was induced in mice by intraperitoneal injection of EAC cells (1×106 cells/mouse). The in vivo antitumor effect of extracts was assessed by monitoring the mean survival time, tumor volume, effect on hematological parameters, determination of lysosome specific cancer markers (cathepsin-D), β-D glucuronidase and acid phosphatase, liver marker enzymes (5’-nuclotidase and lactate dehydrogenase), membrane bound ATPase (Na+/K+ ATPase and Mg2+ ATPase), DNA, and RNA content. Results: The percentage yield obtained were 9.87%w/w, 7.88%w/w, and 16.56% w/w for petroleum ether, ethyl acetate, and ethanol extract, respectively. The phytochemical screenings of those extracts were performed. The order of activity of extracts was ethanol extract > ethyl acetate > petroleum ether. Among the extracts, Ethanol extract of P. corymbosa Lamk. showed a significant increase in life span and decrease in viable cancer cell number and tumor volume. The protective effect of the extract on the hemopoietic system at the dose 200mg∕kg was noted. The alterations in the hematological profile, lysosome-specific cancer markers, liver-specific cancer markers, and membrane-bound ATPases DNA and RNA were restored. Conclusion: The ethanolic extract of P. corymbosa Lamk. possesses in vivo anticancer activity when compared to the tumor control group

Formulation and Evaluation of Sustained Release Matrix Tablets of Lamivudine

From the observations of the said work it could be concluded that slow and controlled release of Lamivudine for more than 12 hours was obtained by using of natural (guar gum) and more than 24 hrs by using semi synthetic polymers (sodium carboxy methyl cellulose). Both the polymers were successful in the formation of matrix and at the same time it is effective in retarding the drug release. The drug release follows first-order kinetics. The mechanism of drug release was diffusion coupled with erosion. Stability studies revealed that there was no significant change in drug content and dissolution profile of matrix tablets. The In vitro studies suggest that a controlled release matrix tablet of Lamivudine with a natural polymer matrix would be promising for therapy of AIDS by minimizing the side effects of the synthetic polymers. A further detailed study in human subjects will through more light on their efficacy and compliance

Android Application to Detect and Alert Tachycardia and Bradycardia using Pulse Rate Sensor

Heart rate monitoring is most vital in preventing disorders related to heart. Failure to detect heart disorder in early stage may lead to death. The lacking of devices to immediately detect the abnormalities in heart and alert the patients emergency contact lead to this problem. In this report the author propose a system to detect two heart disorders called Tachycardia and Bradycardia which are caused by abnormalities in heart rate. The proposed system will consist of a pulse sensor which will be connected to a smartphone via Bluetooth. The signal information which is processed by the microcontroller will be sent to the mobile phone. An app created will send an alert to the emergency contacts of the patients when Tachycardia or Bradycardia condition has been detected by the sensor. This will increase the possibilities of giving immediate treatment to the patient, and hope to reduce the death rate caused by heart disorder

Observation of the hepatoprotective and antioxidant activities of Trianthema decandra Linn. (Vallai sharunnai) roots on carbon tetrachloride-treated rats

The present study was carried out to observe the hepatoprotective effect and antioxidant activity of the ethanol extract of the roots of Trianthema decandra Linn. (200 and 400 mg/kg) in rats treated with carbon tetrachloride for 8 weeks. Extract at the tested doses restored the levels of all serum (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin and total protein) and liver homogenate enzymes (glutathione peroxidase, glutathione reductase, superoxide dismutase and catalase) significantly. Histology demonstrated profound steatosis degeneration and nodule formation were observed in the hepatic architecture of carbon tetrachloride treated rats which were found to acquire near-normalcy in extract plus carbon tetrachloride administrated rats, and supported the biochemical observations. This study suggests that ethanol extract of T. decandra has a liver protective effect against carbon tetrachloride- induced hepatotoxicity and possess antioxidant activities

Classification of COVID-19 Cases: The Customized Deep Convolutional Neural Network and Transfer Learning Approach

The recent advancements under the umbrella of artificial intelligence (AI) open opportunities to tackle complex problems related to image analysis. Recently, the proliferation of COVID-19 brought multiple challenges to medical practitioners, such as precise analysis and classification of COVID-19 cases. Deep learning (DL) and transfer learning (TL) techniques appear to be attractive solutions. To provide the precise classification of COVID-19 cases, this article presents a customized Deep Convolutional Neural Network (DCNN) and pre-trained TL model approach. Our pipeline accommodated several popular pre-trained TL models, namely DenseNet121, ResNet50, InceptionV3, EfficientNetB0, and VGG16, to classify COVID-19 positive and negative cases. We evaluated and compared the performance of these models with a wide range of measures, including accuracy, precision, recall, and F1 score for classifying COVID-19 cases based on chest X-rays. The results demonstrate that our customized DCNN model performed well with randomly assigned weights, achieving 98.5% recall and 97.0% accuracy

Fenton-like degradation of Bisphenol A catalyzed by mesoporous Cu/TUD-1

A family of copper oxide catalysts with loadings spanning 1–5 wt% were dispersed on a three dimensional, mesoporous TUD-1 silica through a hydrothermal, surfactant-free route employing tetraethylene glycol as a structure-directing agent. Their bulk and surface properties were characterized by N2 physisorption, XRD, DRUVS, EPR, TEM and Raman spectroscopy, confirming the expected mesoporous wormhole/foam support morphology and presence of well-dispersed CuO nanoparticles (∼5–20 nm). The catalytic performance of Cu/TUD-1 was evaluated as heterogeneous Fenton-like catalysts for Bisphenol A (BPA) oxidative degradation in the presence of H2O2 as a function of [H2O2], and CuO loading. Up to 90.4% of 100 ppm BPA removal was achieved over 2.5 wt% Cu/TUD-1 within 180 min, with negligible Cu leaching into the treated water

Groundwater Geochemistry of Neyveli Lignite Mine-Industrial Complex, Tamil Nadu, India and Its Suitability for Irrigation

This study was undertaken to assess the quality of groundwater for irrigation and level of trace metal concentration in the surface and groundwater bodies from Neyveli lignite mine-industrial complex which is located in Cuddalore district, Tamil Nadu, India. The hydrogeology of the Neyveli groundwater basin is extremely complex, consisting of a series of productive, confined aquifers below the lignite seam in both Mine I and II areas, while a semi-confined aquifer lies above the seam and occurs only in the Mine II area. The suitability of groundwater quality for agricultural purposes in and around Neyveli lignite mine-industrial complex was assessed by measuring physicochemical parameters, including major cation and anion compositions, pH, total dissolved solids, electrical conductivity, and trace metals. The results of the chemical analysis of the groundwater showed that concentrations of ions vary widely and the most prevalent water type is mixed CaNaHCO3, followed by other water types: mixed CaMgCl types and NaCl which is in relation with their interactions with the geological formations of the basin, dissolution of feldspars and chloride and bicarbonate minerals, and anthropogenic activities. The most dominant class is C1-S1, C2-S1 (85% PRM and 74% POM) in the study area, indicating that sodicity is very low and salinity is medium, and that these waters are suitable for irrigation in almost all soils.Based on sodium absorption ratio the groundwater of the study area is suitable for all types of crops and soil except for those crops sensitive to Na and based RSC values of the groundwater, considered safe. Based on the parameters such as TDS, EC, SO4, Cl and Wilcox diagram about 99% of samples are suitable for irrigation. The average concentration of trace metals (Fe, Mn, Cr, Zn, Pb, and Cu) in groundwater samples fall within the permissible limit, with the exception of Ni which is recorded higher than the permissible limit which may retard growth and metabolic activities while the groundwater used for irrigation