Global parameter test ideals

This paper shows the existence of ideals whose localizations and completions at prime ideals are parameter test ideals of the localized and completed rings. We do this for Cohen-Macaulay localizations (resp., completions) of non-local rings, for generalized Cohen-Macaulay rings, and for non-local rings with isolated non Cohen-Macaulay points, each being an isolated non $F$-rational point. The tools used to prove this results are constructive in nature and as a consequence our results yield algorithms for the computation of these global parameter test ideals. Finally, we illustrate the power of our methods by analyzing the HSL numbers of local cohomology modules with support at any prime ideal

Daily earthquake forecasts during the May-June 2012 Emilia earthquake sequence (northern Italy)

The paper has no abstrac

Intranasal dexmedetomidine and intravenous ketamine for procedural sedation in a child with alpha-mannosidosis: A magic bullet?

Background: Procedural sedation is increasingly needed in pediatrics. Although different drugs or drugs association are available, which is the safest and most efficient has yet to be defined, especially in syndromic children with increased sedation-related risk factors. Case report: we report the case of a five-year-old child affected by alpha-mannosidosis who required procedural sedation for an MRI scan and a lumbar puncture. We administered intranasal dexmedetomidine (4 \u3bcg/kg) 45 min before intravenous cannulation, followed by one bolus of ketamine (1 mg/kg) for each procedure. The patient maintained spontaneous breathing and no desaturation or any complication occurred. Conclusion: intranasal dexmedetomidine and intravenous ketamine could be a feasible option for MRI and lumbar puncture in children with alpha-mannosidosis needing sedation

Spring diet of the pine marten in Sardinia, Italy

Alimentación primaveral de la marta en Cerdeña, ItaliaEl conocimiento del comportamiento de alimentación de un carnívoro es esencial para entender su ecología. La marta Martes martes se define comúnmente como un depredador generalista oportunista, porque su dieta en Europa incluye mamíferos, frutas, aves y invertebrados. A partir del análisis de las heces, hemos descrito los hábitos alimenticios en primavera y la amplitud del nicho trófico de la marta en ambiente mediterráneo en Cerdeña (Italia central). Los pequeños mamíferos (sobre todo Apodemus sylvaticus, Mus musculus y Eliomys quercinus) representan la fuente más importante de alimentación de la marta, ya que constituyen aproximadamente el 52% del volumen medio. Otra fuente importante de alimentos secundarios la constituyen los invertebrados (especialmente escarabajos y larvas de insectos) y las aves (paseriformes casi exclusivamente), mientras que los grandes mamíferos, los lagomorfos, los reptiles y las frutas están poco representados en la dieta. La composición de la dieta y el valor del índice de Levins indican que la marta en Cerdeña es un depredador especialista facultativo, con una especialización en la depredación de los micromamíferos.Knowledge of a carnivore’s foraging behaviour is essential to understand its ecology. The pine marten Martes martes is commonly defined as an opportunistic generalist predator since its diet in Europe includes mammals, fruits, birds and invertebrates. Based on faecal analyses, we evaluated spring feeding habits and trophic niche breadth of the pine marten in a Mediterranean landscape on the island of Sardinia (Central Italy). The most important source of food for the pine marten was small mammals (mainly Apodemus sylvaticus, Mus musculus and Eliomys quercinus), accounting for 52% of the percent mean volume. Important secondary foods were invertebrates (mainly beetles and insect larvae) and birds (almost exclusively passerines), whereas large mammals, lagomorphs, reptiles and fruits made little contribution to the diet. The diet composition and the Levins’ index value suggest that the pine marten in Sardinia behaves as a facultative specialist predator, with a specialization towards small mammals.Alimentación primaveral de la marta en Cerdeña, ItaliaEl conocimiento del comportamiento de alimentación de un carnívoro es esencial para entender su ecología. La marta Martes martes se define comúnmente como un depredador generalista oportunista, porque su dieta en Europa incluye mamíferos, frutas, aves y invertebrados. A partir del análisis de las heces, hemos descrito los hábitos alimenticios en primavera y la amplitud del nicho trófico de la marta en ambiente mediterráneo en Cerdeña (Italia central). Los pequeños mamíferos (sobre todo Apodemus sylvaticus, Mus musculus y Eliomys quercinus) representan la fuente más importante de alimentación de la marta, ya que constituyen aproximadamente el 52% del volumen medio. Otra fuente importante de alimentos secundarios la constituyen los invertebrados (especialmente escarabajos y larvas de insectos) y las aves (paseriformes casi exclusivamente), mientras que los grandes mamíferos, los lagomorfos, los reptiles y las frutas están poco representados en la dieta. La composición de la dieta y el valor del índice de Levins indican que la marta en Cerdeña es un depredador especialista facultativo, con una especialización en la depredación de los micromamíferos

Evidence of Hepatitis E Virus (HEV) infection in human and pigs in Sardinia, Italy

Introduction. The aim of this study was to determine the seroprevalence of anti-HEV antibodies in humans sera and to study HEV prevalence in swine from different Sardinian farms, testing viral HEV-RNA in bile samples. Methods. In the first six months of 2008, 532 subjects of whom 402 blood donors and 130 workers at zoonotic risk, were enrolled. Anti-HEV were determined with an enzyme linked immunosorbent assay (ELISA). In positive subjects, RNA was extracted and tested by RT-Nested-PCR. From July 2006 to March 2007, 95 bile samples were collected from randomly selected pigs. RNA was extracted from 250 ?l of bile and tested by RT-Nested-PCR. Results. The overall prevalence of anti-HEV antibodies was 4.3%; 5.0% among blood donors and 2.3% among workers at zoonotic risk, with no statistically significant differences between sex, age classes and occupation. The search for HEV-RNA in the subjects positive for antibodies, gave negative results. HEV genome was detected in 6 of the 95 swine bile samples tested. Sequences were clustered within the genotype 3 and are edited on GenBank under accession number: from FJ850960 to FJ850962 and from FJ883000 to FJ883002. Discussion. The overall prevalence of anti-HEV shows that the virus circulates without giving origin to cases of acute hepatitis. The low prevalence value found in workers at zoonotic risk do not apparently support the hypothesis of professional risk. In this study, HEV-RNA was isolated from pigs in Sardinia for the first time confirming the role of swine as HEV reservoir and the possibility of virus transmission to humans

Correlation of Static Stress Changes and Earthquake Occurrence in

A systematic analysis is made of static Coulomb stress changes and earthquake occurrence in the area of the North Aegean Sea, Greece, in order to assess the prospect of using static stress changes to construct a regional earthquake likelihood model. The earthquake data set comprises all events of magnitude M ≥ 5.2 which have occurred since 1964. This is compared to the evolving stress field due to constant tectonic loading and perturbations due to coseismic slip associated with major earthquakes (M ≥ 6.4) over the same period. The stress was resolved for sixteen fault orientation classes, covering the observed focal mechanisms of all earthquakes in the region. Analysis using error diagrams shows that earthquake occurrence is better correlated with the constant tectonic loading component of the stress field than with the total stress field changes since 1964, and that little, if any, information on earthquake occurrence is lost if only the maximum of the tectonic loading over the fault orientation classes is considered. Moreover, the information on earthquake occurrence is actually increased by taking the maximum of the evolving stress field since 1964, and of its coseismic–slip component, over the fault orientation classes. The maximum, over fault orientation classes, of linear combinations of the tectonic loading and the evolving stress field is insignificantly better correlated with earthquake occurrence than the maximum of the tectonic loading by itself. A composite stress–change variable is constructed from ordering of the maximum tectonic loading component and the maximum coseismic–slip component, in order to optimize the correlation with earthquake occurrence. The results indicate that it would be difficult to construct a time–varying earthquake likelihood model from the evolving stress field that is more informative than a time–invariant model based on the constant tectonic loading

Clinical course and features of persistent polyclonal B-cell lymphocytosis with BCL-6 amplification during pregnancy

Background: Persistent polyclonal B-cell lymphocytosis is a rare nonmalignant disorder characterized by mild persistent lymphocyte proliferation with possible evolution to aggressive lymphoma. Its biology is not well known, but it is characterized by a specific immunophenotype with rearrangement of the BCL-2/IGH gene, whereas amplification of the BCL-6 gene has rarely been reported. Given the paucity of reports, it has been hypothesized that this disorder is associated with poor pregnancy outcomes. Case report: To our knowledge, only two successful pregnancies have been described in women with this condition. We report the third successful pregnancy in a patient with PPBL and the first with amplification of the BCL-6 gene. Conclusions: PPBL is still a poorly understood clinical condition with insufficient data to demonstrate an adverse effect on pregnancy. The role of BCL-6 dysregulation in the pathogenesis of PPBL and its prognostic significance are still unknown. Evolution into aggressive clonal lymphoproliferative disorders is possible and prolonged hematologic follow-up is warranted in patients with this rare clinical disorder