Piecing Together the Past

Nearly fifty years ago, some Bedouin shepherds stumbled upon a cache of ancient texts in caves near the Dead Sea, thirteen miles east of Jerusalem. It soon became clear that this was the largest and most significant collection of manuscripts ever discovered in Palestine. Finds Included the oldest witnesses to the Hebrew, Aramaic, and Greek texts of Jewish scripture-the Christian Old Testament-along with nonbiblical manuscripts certain to illuminate the tumultuous period of the destruction of the Second Temple and the time of Christ. The singularity of these texts has brought about one of the most protracted and painstaking endeavors of contemporary scholarship on religious history and Scripture. One afternoon 1947, three Bedouin shepherds were herding their flocks in the vicinity of Wadi Qumran above the northwest shore of the Dead Sea. They casually tossed a rock in acave opening and heard something break. Returning later, they discovered ten large pottery jars, one of which contained three scrolls wrapped in protective linen coverings. Four additional scrolls were soon discovered in the cave. Neither the Bedouin nor the antiquities dealer whom they contacted had any idea what the documents contained. Thinking the script to be some form of Syriac, the antiquities dealer solf four of the scrolls to the Syrian Orthodox metropolitan at St. Mark\u27s Monastery in Jerusalem. For approximately one hundred dollars, the metropolitan unwittingly purchased the oldest extant Hebrew text of the Book of Isaiah, an ancient Hebrew commentary on Habakkuk, and two unknown texts. The antiquities dealer sold the other three manuscripts to Eleazar Sukenik, a professor at Hebrew University in Jerusalem. The scrolls were in such fine condition that they were all published almost immediately. The magnitude and antiquity of these finds soon became apparent, and the caves around Wadi Qumran were aggressively explored for additional scrolls. Of the many caves quarried, eleven near the Wadi yielded written material. Cave 11, the last to be discovered (1956), supplied several extensively preserved scrolls of Leviticus, Psalms, and other works whose state of preservation rivaled that of the original Cave 1 finds. Unfortunately, there were only about a dozen of these beautifully preserved scrolls. Most of the approximately eight hundred texts discovered in the Qumran caves were not scrolls but scraps from disintegrated scrolls. Cave 4 yielded its rich cache of more than 575 manuscripts in tens of thousands of pieces. The condition of the written material in the other caves was no better: Caves 2 and 3 and Caves 5 through 10 yielded only fragments of more than one hundred other texts. Lacking the protection of pottery jars and linen shrouds, these manuscripts had fallen prey to a host of aggressors over the centuries, from the moisture in the caves to the appetite of worms to the swords and sandals of the caves\u27 human visitors. The scrolls simply disintegrated over the centuries, with the result that rarely 5 percent of any individual manuscript survived. The few surviving pieces of discrete scrolls were separated from one another and jumbled indiscriminately in layers of dirt on the cave floors. The muddle of fragments was made all the more incomprehensible by the manner of their retrieval. The Bedouin had gathered and sold most of the initial fragments without any record of where they came from. Fortunately, subsequent scientific excavations of Cave 4 unearthed fragments that were manifestly part of the same scrolls represented by the Bedouin finds. This established that the Bedouin scraps had been removed from the floor of Cave 4 and thereby guaranteed the authenticity of the initial fragments

Due Process Implications of Prison Transfers

One of the several anomalies of prison life is the disparate protection afforded inmates transferred to higher security. Although both punitive and administrative transfers often place the inmate in the same building under almost identical conditions, only disciplinary transfers are generally conceded to give rise to due process protection. The inmate confined in isolation for fifteen days as punishment for misconduct is guaranteed a hearing with advance written notice and the rights to present testimony and receive a written decision. On the other hand, the prisoner confined indefinitely in segregation for supposed administrative reasons has such due process rights only if the state decides to provide them. Consequently, the most severe sentence that can be handed down by a committee hearing a disciplinary charge is not fifteen days in isola- tion or loss of good time, but rather the vague and foreboding phrase referred for high security. This article will discuss the background and application of the distinction between the punitive and administrative elements of prison transfers, focusing upon its effects on the due process rights of inmates in Virginia prisons

Artificial Leaf for Biofuel Production and Harvesting: Transport Phenomena and Energy Conversion

textMicroalgae cultivation has received much research attention in recent decades due to its high photosynthetic productivity and ability to produce biofuel feedstocks as well as high value compounds for the health food, cosmetics, and agriculture markets. Microalgae are conventionally grown in open pond raceways or closed photobioreactors. Due to the high water contents of these cultivation systems, they require large energy inputs for pumping and mixing the dilute culture, as well as concentrating and dewatering the resultant biomass. The energy required to operate these systems is generally greater than the energy contained in the resultant biomass, which precludes their use in sustainable biofuel production. To address this challenge, we designed a novel photobioreactor inspired by higher plants. In this synthetic leaf system, a modified transpiration mechanism is used which delivers water and nutrients to photosynthetic cells that grow as a biofilm on a porous, wicking substrate. Nutrient medium flow through the reactor is driven by evaporation, thereby eliminating the need for a pump. This dissertation outlines the design, construction, operation, and modeling of such a synthetic leaf system for energy positive biofuel production. First, a scaled down synthetic leaf reactor was operated alongside a conventional stirred tank photobioreactor. It was demonstrated that the synthetic leaf system required only 4% the working water volume as the conventional reactor, and showed growth rates as high as four times that of the conventional reactor. However, inefficiencies in the synthetic leaf system were identified and attributed to light and nutrient limitation of growth in the biofilm. To address these issues, a modeling study was performed with the aim of balancing the fluxes of photons and nutrients in the synthetic leaf environment. The vascular nutrient medium transport system was also modeled, enabling calculation of nutrient delivery rates as a function of environmental parameters and material properties of the porous membrane. These models were validated using an experimental setup in which the nutrient delivery rate, growth rate, and photosynthetic yield were measured for single synthetic leaves. The synthetic leaf system was shown to be competitive with existing technologies in terms of biomass productivity, while requiring zero energy for nutrient and gas delivery to the microorganisms. Future studies should focus on utilizing the synthetic leaf system for passive harvesting of secreted products in addition to passive nutrient delivery.Mechanical Engineerin

Eugene P. Murphy of Grand Forks: Germany, World War II

North Dakota Prisoner of War Report by Eugene P. Murphy (1919-1989) of Grand Forks. Murphy was a POW of Germany during the Second World War. 21 page

Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration.

BackgroundSkin fibrosis is a significant medical problem that leads to a functional, aesthetic, and psychosocial impact on quality-of-life. Light-emitting diode-generated 633-nm red light (LED-RL) is part of the visible light spectrum that is not known to cause DNA damage and is considered a safe, non-invasive, inexpensive, and portable potential alternative to ultraviolet phototherapy that may change the treatment paradigm of fibrotic skin disease.ObjectiveThe goal of our study was to investigate the how reactive oxygen species (ROS) free radicals generated by high fluence LED-RL inhibit the migration of skin fibroblasts, the main cell type involved in skin fibrosis. Fibroblast migration speed is increased in skin fibrosis, and we studied cellular migration speed of cultured human skin fibroblasts as a surrogate measure of high fluence LED-RL effect on fibroblast function. To ascertain the inhibitory role of LED-RL generated ROS on migration speed, we hypothesized that resveratrol, a potent antioxidant, could prevent the photoinhibitory effects of high fluence LED-RL on fibroblast migration speed.MethodsHigh fluence LED-RL generated ROS were measured by flow cytometry analysis using dihydrorhodamine (DHR). For purposes of comparison, we assessed the effects of ROS generated by hydrogen peroxide (H2O2) on fibroblast migration speed and the ability of resveratrol, a well known antioxidant, to prevent LED-RL and H2O2 generated ROS-associated changes in fibroblast migration speed. To determine whether resveratrol could prevent the high fluence LED-RL ROS-mediated photoinhibition of human skin fibroblast migration, treated cells were incubated with resveratrol at concentrations of 0.0001% and 0.001% for 24 hours, irradiated with high fluences LED-RL of 480, 640, and 800 J/cm2.ResultsHigh fluence LED-RL increases intracellular fibroblast ROS and decreases fibroblast migration speed. LED-RL at 480, 640 and 800 J/cm2 increased ROS levels to 132.8%, 151.0%, and 158.4% relative to matched controls, respectively. These LED-RL associated increases in ROS were prevented by pretreating cells with 0.0001% or 0.001% resveratrol. Next, we quantified the effect of hydrogen peroxide (H2O2)-associated ROS on fibroblast migration speed, and found that while H2O2-associated ROS significantly decreased relative fibroblast migration speed, pretreatment with 0.0001% or 0.001% resveratrol significantly prevented the decreases in migration speed. Furthermore, we found that LED-RL at 480, 640 and 800 J/cm2 decreased fibroblast migration speed to 83.0%, 74.4%, and 68.6% relative to matched controls, respectively. We hypothesized that these decreases in fibroblast migration speed were due to associated increases in ROS generation. Pretreatment with 0.0001% and 0.001% resveratrol prevented the LED-RL associated decreases in migration speed.ConclusionHigh fluence LED-RL increases ROS and is associated with decreased fibroblast migration speed. We provide mechanistic support that the decreased migration speed associated with high fluence LED-RL is mediated by ROS, by demonstrating that resveratrol prevents high fluence LED-RL associated migration speed change. These data lend support to an increasing scientific body of evidence that high fluence LED-RL has anti-fibrotic properties. We hypothesize that our findings may result in a greater understanding of the fundamental mechanisms underlying visible light interaction with skin and we anticipate clinicians and other researchers may utilize these pathways for patient benefit

Engineering Leadership

By 1921 the American sociologist Thorstein Veblen in his book The Engi-neers and the Price System argued for a technocracy in which the welfare of humanity would be entrusted to the control of the engineers because they alone were competent to understand the complexities of the industrial system and processes and thereby optimize and maximize its output. This chapter sets out to explore the extent to which Veblen’s technocratic leadership thesis has come to pass. We first review the role of the engineer in society and in the context of Europe, the US and China, and examine the influence of the engineering profession on the management and economic welfare of nations. Second we review trends in engineering education and formation in Europe, China and the US, and the substantive developmental role of the Grand Écoles in 18th-century France. A comparison is made between the economies of Ireland and China, in the context of their recent economic performance. Third a review of commentary on the interconnectedness of world economies and shift in economic power from nineteenth century United King-dom market dominance to twentieth century United States supremacy and to present day emergence of China as the world’s second largest and fastest growing economy, is made in the context of the role of engineering leadership. We finally ponder whether a hybrid political environment, with blending of meritocracy with technocratic leadership and moderated by non-engineering influences, might be a recipe for sustained economic success of nations

Engineering Science as Opposed to Natural Science

In exploring the epistemology of engineering science, we propose a model of engineering. This model incorporates the goals of engineering, the approach to engineering (also called the engineering method) and the role of experience in engineering. The basis for understanding the nature of engineering science will be explored, and will be contrasted with natural science. To begin, a large-scale engineering project that was successfully completed in Ireland many years ago is discussed - specifically, the development of a megalithic passage tomb as an exemplar of the engineering method in structural design, project management and aesthetics. This exemplar firmly demonstrates that engineering method existed before the development and understanding of the relevant natural science. We next contrast the nature of engineering or engineering science and natural science. This discussion will further develop the engineering model, but will contrast the philosophical differences between engineering and science. We then return to build upon the \u27engineering model\u27 through the modern day exemplar of the development of the jet engine, demonstrating that invariably multiple factors, including creative design initiatives from different sources, global, political, economic and cultural circumstance, and the passage of time contribute to the evolution and success (or failure) of large sustainable scientific and engineering projects. In conclusion, the engineering model is mapped to a philosophical model demonstrating that philosophy is as relevant to engineering as it is to other fields

Engineering Science as Opposed to Natural Science

In exploring the epistemology of engineering science, we propose a model of engineering. This model incorporates the goals of engineering, the approach to engineering (also called the engineering method) and the role of experience in engineering. The basis for understanding the nature of engineering science will be explored, and will be contrasted with natural science. To begin, a large-scale engineering project that was successfully completed in Ireland many years ago is discussed - specifically, the development of a megalithic passage tomb as an exemplar of the engineering method in structural design, project management and aesthetics. This exemplar firmly demonstrates that engineering method existed before the development and understanding of the relevant natural science. We next contrast the nature of engineering or engineering science and natural science. This discussion will further develop the engineering model, but will contrast the philosophical differences between engineering and science. We then return to build upon the \u27engineering model\u27 through the modern day exemplar of the development of the jet engine, demonstrating that invariably multiple factors, including creative design initiatives from different sources, global, political, economic and cultural circumstance, and the passage of time contribute to the evolution and success (or failure) of large sustainable scientific and engineering projects. In conclusion, the engineering model is mapped to a philosophical model demonstrating that philosophy is as relevant to engineering as it is to other fields

Engineering Science as Opposed to Natural and Applied Science

In exploring the epistemology of engineering science we propose a model of engineering. This model incorporates the goals of engineering, the approach to engineering (also called the engineering method) and the role of experience in engi-neering. The basis for understanding the nature of engineering science will be ex-plored, and will be contrasted with natural science. To begin, a large-scale engi-neering project that was successfully completed in Ireland many years ago is dis-cussed - specifically, the development of a megalithic passage tomb as an exemplar of the engineering method in structural design, project management and aesthetics. This exemplar firmly demonstrates that engineering method existed before the de-velopment and understanding of the relevant natural science. We next contrast the nature of engineering or engineering science and natural science. This discussion will further develop the engineering model, but will contrast the philosophical dif-ferences between engineering and science. We then return to build upon the ‘engi-neering model’ through the modern day exemplar of the development of the jet engine, demonstrating that invariably multiple factors, including creative design initiatives from different sources, global, political, economic and cultural circum-stance, and the passage of time contribute to the evolution and success (or failure) of large sustainable scientific and engineering projects. In conclusion, the engineering model is mapped to a philosophical model demonstrating that philosophy is as rele¬vant to engineering as it is to other fields