2,846 research outputs found

    Antitrust Enforcement Encourages Health Care Providers to Cooperate Procompetitively

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    A review of significant administrative and judicial rulings in antitrust law during 1993 shows that the antitrust laws should not impede innovative, cost-cutting cooperative arrangements among providers, so long as their actual or potential procompetitive benefits are not outweighed by their anticompetitive effects

    A successful pregnancy following SEM fine tuning of hormonal priming

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    BACKGROUND: Manipulation of the uterine epithelium utilising standard dose exogenous oestrogen (E(2)) and progesterone (P(4)) has been shown to achieve a mature secretory morphological response. However, in an in vitro fertilisation (IVF) setting, frozen embryo transfer (ET) has had a low success rate. We propose that in patients with previously failed ET attempts, the uterine epithelium can be directly visualised by biopsy and Scanning Electron Microscopy (SEM) and that with an individualised fine tuning of the hormone supplementation regime, based on the SEM examination of sequential uterine biopsies, it is possible to provide a uterine environment conducive to successful ET. METHODS: A 47 year old women was chosen for endometrial biopsy, histopathological dating and endometrial observation utilising SEM to determine the integrity of her secretory uterine epithelium because of her age and several previously failed attempts at frozen ET. Exogenous E(2) and P(4) supplementation was administered in modified doses according to the SEM result, in consecutive cycles until the epithelial response appeared satisfactory for potential implantation. RESULTS: This case study demonstrates the dramatic change in epithelial characteristics that can be achieved as a response to these altered doses of E(2) and P(4). The uterine morphology changed from a hypotrophic to a mature, receptive epithelium such that ET resulted in the birth of healthy twin boys. CONCLUSION: The comparison between the consecutive biopsies in direct response to the SEM analysis and tailored modification of E(2) and P(4) dose clearly demonstrates, in this case, the effectiveness of individual morphological monitoring to maximise the successful outcome of ET

    MAGIICAT V. Orientation of Outflows and Accretion Determine the Kinematics and Column Densities of the Circumgalactic Medium

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    We investigate the dependence of gas kinematics and column densities in the MgII-absorbing circumgalactic medium on galaxy color, azimuthal angle, and inclination to trace baryon cycle processes. Our sample of 30 foreground isolated galaxies at 0.3<zgal<1.00.3<z_{\rm gal}<1.0, imaged with the Hubble Space Telescope, are probed by background quasars within a projected distance of 20<D<11020<D<110 kpc. From the high-resolution (Δv≃6.6\Delta v\simeq 6.6 km s−1^{-1}) quasar spectra, we quantify the extent of the absorber velocity structure with pixel-velocity two-point correlation functions. Absorbers with the largest velocity dispersions are associated with blue, face-on (i<57∘i<57^{\circ}) galaxies probed along the projected minor axis (Φ≥45∘\Phi \geq 45^{\circ}), while those with the smallest velocity dispersions belong to red, face-on galaxies along the minor axis. The velocity structure is similar for edge-on (i≥57∘i \geq 57^{\circ}) galaxies regardless of galaxy color or azimuthal angle, for red galaxies with azimuthal angle, and for blue and red galaxies probed along the projected major axis (Φ<45∘\Phi<45^{\circ}). The cloud column densities for face-on galaxies and red galaxies are smaller than for edge-on galaxies and blue galaxies, respectively. These results are consistent with biconical outflows along the minor axis for star-forming galaxies and accreting and/or rotating gas, which is most easily observed in edge-on galaxies probed along the major axis. Gas entrained in outflows may be fragmented with large velocity dispersions, while gas accreting onto or rotating around galaxies may be more coherent due to large path lengths and smaller velocity dispersions. Quiescent galaxies may exhibit little-to-no outflows along the minor axis, while accretion/rotation may exist along the major axis.Comment: 12 pages, 6 figures, 1 table. Accepted for publication in Ap

    Student Experiences Reporting Sexual and Gender-Based Misconduct to the Title IX Office at a Public State University

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    Twenty-five survivors completed anonymous surveys about reporting sexual and gender-based misconduct to their public university’s Title IX office, including case characteristics, perceptions of the reporting and response process (e.g., helpfulness, respect), and experiences of institutional betrayal and support. Measures and open-ended responses described varied misconduct incidents, reporting behaviors, case outcomes, process issues, and negative process consequences. Additionally, process perceptions correlated with institutional betrayal and support. Findings illuminate how survivors’ Title IX process perceptions relate to experiencing harm or support from larger institutions, and offer insights into developing a Title IX process which maintains student rights and dignity regardless of outcome

    An EPR investigation of binding environments by N-donor chelating exchange resins for Cu extraction from aqueous media

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    EPR and UV−vis spectroscopy were collectively used to characterize a series of Cu(II) binding environments within two chelating exchange resins, Dowex and CuWRAM, used for Cu(II) extraction from aqueous media. A series of well-defined intra- and intermolecular binding sites have been identified as responsible for Cu(II) uptake

    Low Mass Group Environments have no Substantial Impact on the Circumgalactic Medium Metallicity

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    We explore how environment affects the metallicity of the circumgalactic medium (CGM) using 13 low mass galaxy groups (2-5 galaxies) at ⟨zabs⟩=0.25\langle z_{abs}\rangle=0.25 identified near background quasars. Using quasar spectra from HST/COS and from Keck/HIRES or VLT/UVES we measure column densities of, or determine limits on, CGM absorption lines. We use a Markov chain Monte Carlo approach with Cloudy to estimate metallicities of cool (T∼104T\sim10^4K) CGM gas within groups and compare them to CGM metallicities of 47 isolated galaxies. Both group and isolated CGM metallicities span a wide range (−2<-2<[Si/H]<0<0), where the mean group (−0.54±0.22-0.54\pm0.22) and isolated (−0.77±0.14-0.77\pm0.14) CGM metallicities are similar. Group and isolated environments have similar distributions of {\HI} column densities as a function of impact parameter. However, contrary to isolated galaxies, we do not find an anti-correlation between {\HI} column density and the nearest group galaxy impact parameter. We additionally divided the groups by member luminosity ratios (i.e., galaxy-galaxy and galaxy-dwarf groups). While there was no significant difference in their mean metallicities, a modest increase in sample size should allow one to statistically identify a higher CGM metallicity in galaxy-dwarf groups compared to galaxy-galaxy groups. We conclude that either environmental effects have not played an important role in the metallicity of the CGM at this stage and expect that this may only occur when galaxies are strongly interacting or merging, or that some isolated galaxies have higher CGM metallicities due to past interactions. Thus, environment does not seem to be the cause of the CGM metallicity bimodality.Comment: 14 pages, 5 figures, 2 figure sets, 1 machine-readable tabl
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