A Pseudo Shock Theory of Pressure Depression in Externally Pressurized Circular Thrust Gas Bearings

A theoretical investigation of the supersonic pressure depression in externally pressurized circular thrust gas bearings is developed with a pseudo shock wave model which replaces the concentrated normal shock wave model used in the previous paper. The pseudo shock theory on the basis of appropriate assumptions used by Crocco can explain the gradual recovery of pressure after supersonic expansion flow from a single central supply hole

EFFECT OF APPLYING BIO-INPUTS ON PRODUCTION OF HIGH BUSH BLUEBERRY (Vaccinium corymbosum L.) cv. biloxi IN BRAZIL'S FEDERAL DISTRICT

Blueberry production is increasing in Brazil, and growers are turning to bio-inputs or biostimulants to be used on their growth. This has been due to the growing concern about sustainability in the food production chain and the necessity to increase the yield. The current experiment aimed at evaluating the effects of Samurai King, EM-1 and Brutal Plus (Minhofértil) biostimulants on the cultivation of Southern Highbush blueberries (V. corymbosum L.), cultivar 'Biloxi'. The parameters evaluated were plant height (cm), diameter of the main stem (mm), number of shoots, chlorophyll content, total number of leaves, leaf length and width. The total mass, number of fruits, average mass per fruit, the transversal and longitudinal diameters, and the total sugars (°Brix) were also measured. In 2020, the treatment of Samurai King + EM-1 showed the highest efficiency for the studied parameters related to fruits and yield but with no significant difference as compared to the other treatments. Regarding the plant growth, treatments 1 (Brutal Plus) and 5 (Brutal Plus + EM-1) were the most efficient. In 2021, treatment 7 (Brutal Plus + Samurai King + EM-1) had the highest yields, except for average mass per fruit and total sugars. In the two years of evaluation, although treatments obtained lower averages than the control, the effect observed was generally positive, revealing the efficiency of products containing microorganisms for the growth of blueberry plants. In conclusion, these bioproducts could remarkably affect plant biomass, production and fruit quality, resulting in better yields

Phamacogenomics of Clozapine-Induced Agranulocytosis

Background: Clozapine-induced agranulocytosis (CIA)/clozapine-induced granulocytopenia (CIG) (CIAG) is a life-threatening event for schizophrenic subjects treated with clozapine. Methods: To examine the genetic factor for CIAG, a genome-wide pharmacogenomic analysis was conducted using 50 subjects with CIAG and 2905 control subjects. Results: We identified a significant association in the human leukocyte antigen (HLA) region (rs1800625, p = 3.46 × 10−9, odds ratio [OR] = 3.8); therefore, subsequent HLA typing was performed. We detected a significant association of HLA-B*59:01 with CIAG (p = 3.81 × 10−8, OR = 10.7) and confirmed this association by comparing with an independent clozapine-tolerant control group (n = 380, p = 2.97 × 10−5, OR = 6.3). As we observed that the OR of CIA (OR: 9.3~15.8) was approximately double that in CIG (OR: 4.4~7.4), we hypothesized that the CIG subjects were a mixed population of those who potentially would develop CIA and those who would not develop CIA (non-CIA). This hypothesis allowed the proportion of the CIG who were non-CIA to be calculated, enabling us to estimate the positive predictive value of the nonrisk allele on non-CIA in CIG subjects. Assuming this model, we estimated that 1) ~50% of CIG subjects would be non-CIA; and 2) ~60% of the CIG subjects without the risk allele would be non-CIA and therefore not expected to develop CIA. Conclusions: Our results suggest that HLA-B*59:01 is a risk factor for CIAG in the Japanese population. Furthermore, if our model is true, the results suggest that rechallenging certain CIG subjects with clozapine may not be always contraindicated

Effect of the environment and use of alternative products in the post-harvest of papaya

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Programa de Pós-Graduação em Agronomia, 2018.O mamão Formosa (Carica papaya L.), em razão de ter como características elevados teor de umidade e taxas respiratórias e ser facilmente danificável, pode sofrer perdas pela falta de comercialização ou de consumo em tempo hábil. Além disso, fatores pré e pós-colheita, como patógenos e fatores abióticos, podem levar a perdas quantitativas e qualitativas. Visando aumentar a vida útil e reduzir as perdas pós-colheita, este trabalho teve por objetivo estabelecer o melhor tratamento alternativo para a conservação pós-colheita de mamão Formosa “Tainung 1” e para o controle da principais doenças (antracnose e podridão peduncular). Para o ensaio de conservação pós-colheita, foram avaliados dois tipos de armazenamento (dentro e fora de câmara fria); seis tratamentos (1- testemunha, 2- Samurai 40 mL/20 litro de água, 3- Serenade® 40 mL/20 litro de água, 4- fungicida EUPROOFF® 10 mL/20 litro de água, 5- EUPROOFF® + Serenade® + Samurai, 6- Serenade® + Samurai), cinco períodos de armazenamento (0, 3, 6, 9 e 12 dias) em três épocas (Dezembro, Janeiro e Fevereiro). Utilizado fungicidas convencionais e produtos de biocontrole. Perda de massa, coloração da casca (Hunter Lab), presença ou ausência de doença, número e tamanho das manchas de doença foram registrados em cada dia de avaliação e analisados. Quanto à massa e cor das frutas, elas mudaram em cada dia de avaliação, mas a mudança foi lenta na situação de preservação refrigerada, a qualidade foi estável. Além disso, os tratamentos não afetaram as alterações na massa ou cor do fruto. Mesmo em relação às doenças, a ocorrência e a progressão foram lentas sob condições refrigeradas de armazenamento e a qualidade foi mais estável. No tratamento, o uso de Samurai sozinho foi mais eficaz. Também misturando Samurai com outros produtos não foi eficaz. Usando Samurai sozinho em condições de armazenamento na câmara fria foi mais eficaz.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).The Formosa papaya (Carica papaya L.), due to characteristics such as the high moisture content and high respiratory rates and be easily damaged, may suffer great losses if not commercialized and not consumed in a timely manner. Additionally, pre-and post-harvest factors as pathogens and abiotic factors can lead to quantitative and qualitative losses. In creasing life shelf and to reduce post-harvest losses, this study aimed to establish the best alternative treatment for post-harvest conservation of Formosa papaya "Tainung 1" and to control major diseases (anthracnose and stem-end rot). For the post-harvest conservation testwere evaluated two types of storage (inside and outside the cold room); Six treatments (1-control, 2-Samurai 40 mL / 20 L water, 3-Serenade® 40 mL / 20 L water, 4-fungicide EUPROOFF® 10 mL / 20 L water, 5- EUPROOFF® + Serenade® + Samurai, 6- Serenade® + Samurai), five storage periods (0, 3, 6, 9 and 12 days) and three seasons(December, January and February). Used conventional fungicides and biocontrol products. Mass loss, color (HunterLab), presence or absence of disease, number and size of disease patches were recorded on each evaluation day and analyzed. As for the mass and color of the fruits, they changed on each evaluation day, but the change was slow in the refrigerated preservation situation, the quality was stable. In addition, the treatments did not affect the changes in fruit mass or color. Even with regard to diseases, the occurrence and progression were slow under refrigerated storage conditions and the quality was more stable. In the treatment, the use of Samurai only was more effective. Also mixing Samurai with other products was not effective. Using Samurai only in cold storage conditions was more effective

Effects of Ti Addition on Austenite Grain Growth during Reheating of As-Cast 0.2 mass% Carbon Steel

Effects of Ti addition on grain growth in reversely-transformed austenite structure during reheating of the as-cast 0.2 mass% C steel have been investigated for a Ti concentration range between 0 and 0.2 mass% and heating rates from 0.014 to 2.5°C/s. The austenite grain growth during reheating is retarded by the Ti addition and such an effect becomes stronger with the addition of higher amount of Ti. This retarding effect is ascribable to the pinning effect of fine Ti(C,N) particles which should precipitate from the as-cast structure during the reheating process. The experimental results on the grain growth behavior are well explained by the grain growth model including the Zener force and counting reduction of the pinning effect due to the existence of the coarse Ti(C,N) particles crystallized during the solidification

Origin of the Diplazium hachijoense complex (Athyriaceae)

We analyzed the phylogeny of the Diplazium hachijoense complex using plastid trnL-F and low-copy nuclear marker AK1 DNA sequences. Based on allele constitution, triploid apogamous species of the D. hachijoense complex appeared to have originated from the hybridization of triploid apogamous species and diploid sexual species by recurrent hybridization events. These results suggested that triploid apogamous ferns can achieve hybridization with diploid sexual species by producing diploid spores with irregular meiosis in sporogenesis. Furthermore, the present study predicted the involvement of several unknown species associated with hybridization. More sampling of Callipteris species from China and adjacent areas is required to determine the relationships among unknown species and the D. hachijoense complex

Difference in tissue temperature change between two cryoballoons

Background Cryoballoon ablation, especially Arctic Front Advance Pro (AFA-Pro) (Medtronic, Minneapolis, Minnesota, USA), has been widely recognised as a standard approach to atrial fibrillation (AF). Recently, Boston Scientific has released a novel cryoballoon system (POLARx). Despite comparable acute clinical outcomes of these two cryoballoons, the recent study reported a higher complication rate, especially for phrenic nerve palsy, with POLARx. However, their impact on biological tissue remains unclear.Objective The purpose of our study is to evaluate temperature change of biological tissue during cryoablation of each cryoballoon using a porcine experimental model.Method A tissue-based pulmonary vein model was constructed from porcine myocardial tissue and placed on a stage designed to simulate pulmonary vein anatomy and venous flow. Controlled cryoablations of AFA-Pro and POLARx were performed in this model to evaluate the tissue temperature. A temperature sensor was set behind the muscle and cryoballoon ablation was performed after confirming the occlusion of pulmonary vein with cryoballoon.Results The mean tissue nadir temperature during cryoablation with AFA-Pro was −41.5°C±4.9°C, while the mean tissue nadir temperature during cryoablation with POLARx was −58.4°C±5.9°C (p<0.001). The mean balloon nadir temperature during cryoablation with AFA-Pro was −54.6°C±2.6°C and the mean balloon nadir temperature during cryoablation with POLARx was −64.7°C±3.8°C (p<0.001).Conclusion POLARx could freeze the biological tissue more strongly than AFA-Pro