7 research outputs found
Chlamydia trachomatis samples testing falsely negative in the Aptima Combo 2 test in Finland, 2019
Get PDFSince February 2019, over 160 Chlamydia trachomatis (CT) cases testing negative or equivocal by Aptima Combo 2 (AC2) but positive by Aptima CT test run with Panther instruments occurred in Finland. The AC2 test targets chlamydial 23S rRNA while the CT test targets 16S rRNA. Sequencing of 10 strains revealed a nucleotide substitution in 23S rRNA. The significance of this for the failure of the AC2 test to detect the variant is not yet known.Peer reviewe
Lymen borrelioosin epidemiologinen seuranta : Ohje kliinisen mikrobiologian laboratorioille seurantatiedon yhtenäistämiseksi
Get PDFChlamydia trachomatis samples testing falsely negative in the Aptima Combo 2 test in Finland, 2019
Get PDFSince February 2019, over 160 Chlamydia trachomatis (CT) cases testing negative or equivocal by Aptima Combo 2 (AC2) but positive by Aptima CT test run with Panther instruments occurred in Finland. The AC2 test targets chlamydial 23S rRNA while the CT test targets 16S rRNA. Sequencing of 10 strains revealed a nucleotide substitution in 23S rRNA. The significance of this for the failure of the AC2 test to detect the variant is not yet known
Cellular defense mechanisms in experimental murine salmonellosis : specific immunity and role of IFN-gamma
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