Exogenous Ketone Salt Supplementation and Whole-Body Cooling Do Not Improve Short-Term Physical Performance

Publisher Copyright: © Copyright © 2021 Clark, Munten, Herzig and Gagnon.Exogenous ketone supplementation and whole-body cooling (WBC) have shown to independently influence exercise metabolism. Whether readily available ketone salts, with and without WBC, would provide similar metabolic benefits during steady-state aerobic and time-trial performances was investigated. Nine active males (VO2peak: 56.3 ± 2.2 mL·kg−1·min−1) completed three single-blind exercise sessions preceded by: (1) ingestion of placebo (CON), (2) ketone supplementation (0.3 g·kg−1 β-OHB) (KET), and (3) ketone supplementation with WBC (KETCO). Participants cycled in steady-state (SS, 60% Wmax) condition for 30-min, immediately followed by a 15-min time trial (TT). Skin and core temperature, cardio-metabolic, and respiratory measures were collected continuously, whereas venous blood samples were collected before and after supplementation, after SS and TT. Venous β-OHB was elevated, while blood glucose was lower, with supplementation vs. CON (p < 0.05). TT power output was not different between conditions (p = 0.112, CON: 190 ± 43.5 W, KET: 185 ± 40.4 W, KETCO: 211 ± 50.7 W). RER was higher during KETCO (0.97 ± 0.09) compared to both CON (0.88 ± 0.04, p = 0.012) and KET (0.88 ± 0.05, p = 0.014). Ketone salt supplementation and WBC prior to short-term exercise sufficiently increase blood β-OHB concentrations, but do not benefit metabolic shifts in fuel utilization or improve time trial performance.Peer reviewe

Impact sur les banques des ratios de liquidité de Bâle III : le cas du Luxembourg

Ce mémoire examine les externalités négatives qui accompagnent les nouveaux ratios de mesure de la liquidité introduits par Bâle III. Le ratio de liquidité à court terme, le LCR, et le ratio de financement stable, le NSFR visent à promouvoir une structure de financement adéquate en termes de liquidité au vu des activités de la banque. Bien que l’intention du législateur soit louable, les changements réglementaires s’accompagnent souvent d’externalités négatives. Ce mémoire s’emploie dans un premier temps à présenter les principales contraintes réglementaires et le contexte macroéconomique qui les entoure. L’objectif général est d’identifier les externalités négatives sur les banques avec une attention plus particulière au cas du Luxembourg, centre financier par excellence. Ce mémoire contient, entre autres, des illustrations destinées à faciliter la compréhension d’éléments techniques, une étude de cas théorique, et des interviews d’acteurs clefs de la place luxembourgeoise.Master [120] en Ingénieur de gestion, Université catholique de Louvain, 201

Product service-systems : an integrative typology of value propositions and marketing practices to curb obsolescence practices ? Understanding consumers’ reactions to product-service systems

Faced with the inherent limits of the planet and the need to reduce waste disposal, our society needs to shift towards more sustainable patterns of production and consumption. In this context, we adopt a focus on product-service systems (PSS), the integrated systems of products and services that aim to be competitive, satisfy consumer needs, and have a lower environmental impact than traditional business models. In particular, the three essays of this dissertation investigate whether and how PSS help curb obsolescence practices and how consumers respond to these systems in a business-to-consumer context. The fight against obsolescence (i.e., ‘the deliberate curtailment of product lifespan and the symbolic devaluation of durable goods’) has a leading role to play on environmental development challenges, but academic research on the topic is scarce. A conceptual paper first highlights how product-oriented PSS can reduce the probability of obsolescence occurrence and increase the life cycle (i.e., delaying time to obsolescence) of durable products. We detail the particularities of each sub-practice of product-oriented PSS (i.e., consumer education, take-back schemes and revalorization services, maintenance contracts and repair services, and upgrades), which displays equivocal relationships to the different types of obsolescence (physical, technical, after-sales, economic, psychological, and ecological) and outline a clear research agenda, delineating priorities and paths toward new ways of thinking about PSS. In the second essay, we narrow down our focus to one type of product-oriented PSS sub-practice: repair services. We examine repair within a signaling framework to determine the suitability of repairability communication as a signal of high-quality, durable goods. We employ mixed-methods research to determine how and when informing consumers about a brand promise of repairability through pre-purchase communication can influence their attitude toward the product and the brand. The last essay focuses on use-oriented PSS, characterized by access-based consumption. Based on a case research methodology, this paper aims to advance our understanding of consumers’ experiences with use-oriented PSS and how it shapes consumers’ demand for the product/services or other consumption. We report the emergence of behavioral responses to the adoption of use-oriented PSS that threaten or reinforce the expected environmental gain of these systems. These behavioral responses (i.e. rebound effects) are discussed in light of the coping and the optimal stimulation level literatures. By providing an understanding of PSS as a potential solution against obsolescence, this doctoral dissertation contributes to PSS literature linked to environmental sustainability by investigating the challenges brought by obsolescence and by highlighting the importance of product-oriented PSS. This dissertation also contributes to the sustainable marketing literature by extending the comprehension of consumer behavior regarding potential solutions for obsolescence. From a practical point of view, this dissertation provides managers and policy-makers with insight and guidance to enable the transition to sustainable development and minimized obsolescence.(ECGE - Sciences économiques et de gestion) -- UCL, 202

Patient experiences with full electronic access to health records and clinical notes through the My HealtheVet personal health record pilot: qualitative study

Onderzoek in de Verenigde Staten naar opvattingen en ervaringen van patiënten met het online inzien van hun eigen dossier (personal health record, PHR), inclusief aantekeningen van de behandelaren

Implementation of evidence based practice in mental health nursing: An action research study

This thesis describes an Action Research (AR) project aimed at the implementation of Evidence Based Practice in a mental health nursing setting in the Netherlands. The main research question addressed in this thesis is: In what way is Action Research with an empowering appropriate to implement Evidence Based Practice in a mental health nursing setting in the Netherlands and what is the effect of this implementation on the care experienced by the client, the nursing interventions and the context in this setting compared to a comparative setting? To answer this main research question, the following questions derived from it were addressed: What is Evidence Based Practice? What is known about implementing evidence-based practice in nursing through Action Research? Which factors have to be dealt with in a mental health nursing setting, so the implementation of EBP with AR with an empowering intent will be more successful? Which factors have to be dealt with in a mental health nursing setting, so the implementation of EBP with AR with an empowering intent will be successful? How is EBP implemented through AR with an empowering intent and what are the outcomes for the use of evidence, the context and the facilitation in the setting? What is the effect of the implementation of EBP in mental health nursing using AR with an empowering intent on the care experienced by the client, the nursing interventions and the context compared to a comparison setting? The first two questions were answered by a search of the literature while the remaining questions were answered during the AR study conducted in two mental health organisations in the Netherlands

Multi-dimensional challenges in geriatric rehabilitation: academisch proefschrift: Bianca Buijck / Radboud Universiteit Nijmegen

In dit toegankelijk geschreven en mooi vormgegeven proefschrift van Buijck ligt de focus op de multidisciplinaire revalidatie van patiënten met een beroerte of een prothese, die worden behandeld en begeleid op gespecialiseerde revalidatieafdelingen in verpleeghuizen

Innovations in mental health services:What are the key components of success?

Er wordt voortdurend gestreefd om de zorg te verbeteren door vernieuwingen te implementeren. Dit vindt plaats terwijl we eigenlijk nog maar weinig weten over de factoren die van invloed zijn op zo'n implementatie en hoe deze factoren te beïnvloeden zijn, zodat de kans op een succesvolle implementatie groter wordt. Dit in de UK uitgevoerd onderzoek heeft dan ook als doel om meer inzicht te verwerven in de positieve en belemmerende factoren die bij de invoering van een vernieuwing in de GGZ een rol spelen

Review: exploring the role of mental health nurse-practitioner in the treatment of early psychosis

Verpleegkundig specialisten (VS) hebben in Nederland, net als in andere landen, sinds enige tijd hun plaats veroverd in de gezondheidszorg. In de ggz komt de VS onder meer in aanraking met cliënten met een eerste psychose. In dit literatuuronderzoek is gekeken naar het effect van de interventies tijdens de eerste psychose en de rol van de VS daarbij

Implementeren van EBP in de psychiatrische verpleegkunde door middel van handelingsonderzoek

Hoewel Evidence Based Practice (EBP) in de verpleegkundige literatuur een veelgebruikte term is, geeft diezelfde literatuur aan dat dit niet wil zeggen dat de verpleegkundige praktijk ook evidence-based is. Hier zijn verschillende redenen voor te geven, waaronder de verklaring dat de wereld van de verpleegkundige praktijk en de wereld van het verpleegkundig onderzoek twee afzonderlijke werelden zijn. Aangezien in handelingsonderzoek deze beide werelden worden verbonden is deze methode gebruikt om EBP te implementeren in een psychiatrische verpleegkundige setting. In dit artikel wordt een deel beschreven van dit handelingsonderzoe