710 research outputs found
Application of game theory in ad- hoc opportunistic radios
The application of mathematical analysis to the study
of wireless ad hoc networks has met with limited success due
to the complexity of mobility, traffic models and the dynamic
topology. A scenario based UMTS TDD opportunistic cellular
system with an ad hoc behaviour that operates over UMTS
FDD licensed cellular network is considered. In this paper, we
describe how ad hoc opportunistic radio can be modeled as a
game and how we apply game theory based Power Control in
ad-hoc opportunistic radio
Laparoscopic cervicopexy in uterine prolapse, a prospective study
Background: Pelvic organ prolapse is a common condition and a major cause of gynecological surgery. The lifetime risk of having an operation for prolapse may be 11%. Uterine conserving surgeries using synthetic mesh, especially in younger age group can restore normal anatomy relieving their pelvic symptoms. To evaluate the safety, intra operative and postoperative complications and efficacy of the laparoscopic cervicopexy.Methods: This Prospective observational study was carried out on women aged below 45 years attending gynaecology outpatient department with uterine prolapse at MES Medical College, Perinthalmanna between January 1st and December 31st, 2015. 39 women underwent laparoscopic cervicopexy and follow up assessments was done among them at 2 weeks, 3 months and 6 months. Results: The mean operative time was 27.6 minutes and blood loss was 0.4 gm/dl. No intraoperative and postoperative complications occurred. Short duration of hospital stay with mean of 1.4 days. 7.7% patients and 5.5% had mersilene tape reaction at 3 months and 6 months. The POP Q score C was significantly away from hymen at 2 weeks,3 months and 6 months (+4.4 - -4.3). 7.7% and 2.6% had recurrence at 3 month and 6 months. 5.1% underwent vaginal hysterectomy to get relieved from symptom.Conclusion: Laparoscopic cervicopexy is an effective option for women with pelvic organ prolapse who desire uterine preservation
Nonlinear Propagation in Multimode and Multicore Fibers: Generalization of the Manakov Equations
This paper starts by an investigation of nonlinear transmission in
space-division multiplexed (SDM) systems using multimode fibers exhibiting a
rapidly varying birefringence. A primary objective is to generalize the Manakov
equations, well known in the case of single-mode fibers. We first investigate a
reference case where linear coupling among the spatial modes of the fiber is
weak and after averaging over birefringence fluctuations, we obtain new Manakov
equations for multimode fibers. Such an averaging reduces the number of
intermodal nonlinear terms drastically since all four-wave-mixing terms average
out. Cross-phase modulation terms still affect multimode transmission but their
effectiveness is reduced. We then verify the accuracy of our new Manakov
equations by transmitting multiple PDM-QPSK signals over different modes of a
multimode fiber and comparing the numerical results with those obtained by
solving the full stochastic equation. The agreement is excellent in all cases
studied. A great benefit of the new equations is to reduce the computation time
by a factor of 10 or more. Another important feature observed is that
birefringence fluctuations improve system performance by reducing the impact of
fiber nonlinearities. Finally multimode fibers with strong random coupling
among all spatial modes are considered. Linear coupling is modeled using the
random matrix theory approach. We derive new Manakov equations for multimode
fibers in that regime and show that such fibers can perform better than
single-modes fiber for large number of propagating spatial modes.Comment: Submitted to journal of lightwave technology on the 17-Jul-2012. Ref
number: JLT-14391-201
Developmental regulation of canonical and small ORF translation from mRNAs
Background: Ribosomal profiling has revealed the translation of thousands of sequences outside annotated protein-coding genes, including small open reading frames of less than 100 codons, and the translational regulation of many genes. Here we present an improved version of Poly-Ribo-Seq and apply it to Drosophila melanogaster embryos to extend the catalog of in vivo translated small ORFs, and to reveal the translational regulation of both small and canonical ORFs from mRNAs across embryogenesis.
Results: We obtain highly correlated samples across five embryonic stages, with nearly 500 million putative ribosomal footprints mapped to mRNAs, and compare them to existing Ribo-Seq and proteomic data. Our analysis reveals, for the first time in Drosophila, footprints mapping to codons in a phased pattern, the hallmark of productive translation. We propose a simple binomial probability metric to ascertain translation probability. Our results also reveal reproducible ribosomal binding apparently not resulting in productive translation. This non-productive ribosomal binding seems to be especially prevalent amongst upstream short ORFs located in the 5′ mRNA leaders, and amongst canonical ORFs during the activation of the zygotic translatome at the maternal-to zygotic transition.
Conclusions: We suggest that this non-productive ribosomal binding might be due to cis-regulatory ribosomal binding and to defective ribosomal scanning of ORFs outside periods of productive translation. Our results are compatible with the main function of upstream short ORFs being to buffer the translation of canonical canonical ORFs; and show that, in general, small ORFs in mRNAs display markers compatible with an evolutionary transitory state towards full coding function
Customised Alloy Blends for In-Situ Al339 Alloy Formation Using Anchorless Selective Laser Melting
The additive manufacturing process Selective Laser Melting (SLM) can generate large
thermal gradients during the processing of metallic powder; this can in turn lead to increased residual
stress formation within a component. Metal anchors or support structures are required to be built
during the process and forcibly hold SLM components to a substrate plate and minimise geometric
distortion/warpage due to the process induced thermal residual stress. The requirement for support
structures can limit the geometric freedom of the SLM process and increase post-processing operations.
A novel method known as Anchorless Selective Laser Melting (ASLM) maintains processed material
within a stress relieved state throughout the duration of a build. As a result, metal components formed
using ASLM do not develop signification residual stresses within the process, thus, the conventional
support structures or anchors used are not required to prevent geometric distortion. ASLM locally
melts two or more compositionally distinct powdered materials that alloy under the action of the laser,
forming into various combinations of hypo/hyper eutectic alloys with a new reduced solidification
temperature. This new alloy is maintained in a semi-solid or stress reduced state for a prolonged
period during the build with the assistance of elevated powder bed pre-heating. In this paper, custom
blends of alloys are designed, manufactured and processed using ASLM. The purpose of this work is
to create an Al339 alloy from compositionally distinct powder blends. The in-situ alloying of this
material and ASLM processing conditions allowed components to be built in a stress-relieved state,
enabling the manufacture of overhanging and unsupported features
New-Onset Heart Failure and Ischemic Stroke in Non-compaction Cardiomyopathy: A Case Report
Left ventricular non-compaction (LVNC) cardiomyopathy is an embryological disorder of endocardial trabeculation and can cause heart failure, arrhythmias, and thromboembolism. Lifelong anticoagulation is indicated in patients with reduced ejection fraction due to high risks of thromboembolism. Reduced ejection fraction can develop in these patients as a consequence of this cardiomyopathy, thereby increasing the risk of intracardiac thrombus formation. This new-onset reduced ejection fraction may develop rapidly, which may not be amenable to detection by routine screening. We present a case of non-compaction cardiomyopathy (NCC) with a previously normal ejection fraction who had an ischemic stroke and was found to have new-onset reduced ejection fraction
Financial regimes and uncertainty shocks
Financial markets are central to the transmission of uncertainty shocks. This paper
documents a new aspect of the interaction between the two by showing that uncertainty
shocks have radically di¤erent macroeconomic implications depending on the state finan-
cial markets are in when they occur. Using monthly US data, we estimate a nonlinear
VAR where economic uncertainty is proxied by the (unobserved) volatility of the struc-
tural shocks, and a regime change occurs whenever credit conditions cross a critical
threshold. An exogenous increase in uncertainty has recessionary e¤ects in both good
and bad credit regimes, but its impact on output is estimated to be five times larger
when the economy is experiencing financial distress. Accounting for this nonlinearity,
uncertainty accounts for about 1% of the peak fall in industrial production observed in
the 2007-2009 recession
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