Phagocytes and the Lung

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72927/1/j.1749-6632.1997.tb46258.x.pd

Erectile dysfunction and its detection in the health care setting: 10 years on

Erectile dysfunction is considered an early indicator of cardiovascular disease. Jackson highlighted the important role that General Practitioners and other health care professionals have in detecting erectile dysfunction and potentially preventing subsequent cardiovascular events.(1) Results from our audit suggest that erectile dysfunction detection remains poor

Being on the Juvenile Dermatomyositis Rollercoaster: a qualitative study

Objectives: Juvenile Dermatomyositis is a rare, potentially life-threatening condition with no known cure. There is no published literature capturinghow children and young people feel about their condition, from their perspective. This study was therefore unique in that it asked children and young people what is it like to live with Juvenile Dermatomyositis. Methods: Data wereobtained from fifteen young people with Juvenile Dermatomyositis, between eightand nineteen years of age from one Paediatric Rheumatology department using audio-recordedinterpretive phenomenology interviews. Data were analyzed phenomenologically, using a process that derives narratives from transcripts resulting in a collective composite of participants shared experiences, called a‘phenomenon’. Results:The overarching metaphor of a rollercoaster captures the phenomenon of living withJuvenile Dermatomyositisas a young person, with the ups and downs at different time points clearly described by those interviewed. The five themes plotted on the rollercoaster, began with confusion; followed by feeling different, being sick, steroidal and scared from the medications; uncertainty; and then ended with acceptance of the disease over time. Conclusion: Young people were able to talk about their experiences about having Juvenile Dermatomyositis. Our findings will aid clinicians in their practice by gaining a deeper understanding of what daily life is like and highlighting ways to enhance psychosocial functioning. Hopefully, this study and any further resulting studies,will raise understanding of Juvenile Dermatomyositis worldwide and will encourage health care professionals to better assess psychosocial needs in the future

Cardiorespiratory Fitness and Cancer in Women

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Mapping the current psychology provision for children and young people with juvenile dermatomyositis

Objectives: Juvenile Dermatomyositis (JDM) is a rare, chronic autoimmune condition of childhood, with known psychosocial implications. In this study, we sought to establish current psychological support for children and young people across the UK with rheumatic conditions, with a specific focus on those with JDM. Methods: Electronic surveys were distributed to the 15 centres that belong to the JDM Research Group in the UK, collecting responses from health-care professionals in the fields of medicine, nursing and psychology. Results: One hundred per cent of professionals from medicine and nursing replied from all 15 centres. Of these, 7 (47%) did not have a named psychologist as part of their rheumatology team, despite the majority [13 (87%)] having >200 paediatric rheumatology patients. Of the remaining centres, hospital psychology provision varied considerably. When rating their service, only 3 (8%) of 40 professionals scored their service as five (where one is poor and five is excellent); there were wide discrepancies in these scores. Many challenges were discussed, including limited psychology provision, lack of time and difficulties in offering support across large geographical areas. Conclusion: Many of the challenges discussed are applicable to other centres worldwide. Suggestions have been proposed that might help to improve the situation for children and young people with rheumatic conditions, including JDM. Based on these findings, we suggest that rheumatology teams maximize use of these data to advocate and work toward more comprehensive psychology provision and support in their individual centres

The missing link: explaining ELF static linking, semantically

Beneath the surface, software usually depends on complex linker behaviour to work as intended. Even linking <pre>hello_world.c</pre> is surprisingly involved, and systems software such as <pre>libc</pre> and operating system kernels rely on a host of linker features. But linking is poorly understood by working programmers and has largely been neglected by language researchers. In this paper we survey the many use-cases that linkers support and the poorly specified linker speak by which they are controlled: metadata in object files, command-line options, and linker-script language. We provide the first validated formalisation of a realistic executable and linkable format (ELF), and capture aspects of the Application Binary Interfaces for four mainstream platforms (AArch64, AMD64, Power64, and IA32). Using these, we develop an executable specification of static linking, covering (among other things) enough to link small C programs (we use the example of bzip2) into a correctly running executable. We provide our specification in Lem and Isabelle/HOL forms. This is the first formal specification of mainstream linking. We have used the Isabelle/HOL version to prove a sample correctness property for one case of AMD64 ABI relocation, demonstrating that the specification supports formal proof, and as a first step towards the much more ambitious goal of verified linking. Our work should enable several novel strands of research, including linker-aware verified compilation and program analysis, and better languages for controlling linking. We acknowledge funding from EPSRC grants EP/H005633 (Leadership Fellowship, Sewell) and EP/K008528 (REMS: Rigorous Engineering for Mainstream Systems Programme Grant).This is the final version of the article. It first appeared from Association for Computing Machinery via https://doi.org/10.1145/3022671.298399