147 research outputs found
Comparison of 2-way versus metered 3-way boom shut-off valves for automatic section control on agricultural sprayers
Modern spray rate controllers along with technologies such as automatic section control (ASC) provide benefits such as overlap reduction on agricultural sprayers. However, product (liquid) dynamics within the boom plumbing affect off-rate errors and application uniformity during rate changes and ASC actuation. Therefore, this study was conducted to compare nozzle flow stability and uniformity across the boom when using two different boom shut-off valves (2-way and metered 3-way) on an 18.3-m sprayer boom. Pressure transducers were mounted at 1) the boom manifold, 2) randomly at 12 nozzle bodies across the spray boom, and 3) upstream and downstream of the flow regulating valve. Effective system flow rate was measured using two flow meter(s), one located upstream of the boom control valves (2-way or metered 3-way) and another mounted to measure the tank return flow for the metered 3-way boom valve. Measured nozzle pressure was converted to nozzle flow using the manufacturer’s pressure-flow data. Results indicated that the 2-way boom versus metered 3-way valve response was significantly different. Significant differences in damping ratios were found when exiting (under-damped) and reentering (over-damped) of spray zones. For the metered 3-way boom valve configuration, nozzle flow settled faster (0.1 to 4.2 s) virtually eliminating off-rate errors whereas the 2-way boom valve configuration took up to 34.3 s to settle with off-rate errors ranging from 3.3% to 11.5%. The delayed nozzle flow settling times were associated with pressure settling (0.7 to 31.4 s) downstream of the regulating valve for the 2-way configuration. Ground speed and point row angle impacted nozzle flow settling times and off-rate errors. The increase in ground speed and point row angle increased nozzle flow settling time for the 2-way valve setup, except that acceleration decreased settling times when exiting spray zones. The delayed response contributed to off-rate time which decreased as the sprayer accelerated and point row angle decreased for both the 2-way (1.7 to 19.3 s) and metered 3-way (2.1 to 4.4 s) boom shut-off valve setups
Review: Physiological Growth Trend of Current Meat Broilers and Dietary Protein and Energy Management Approaches for Sustainable Broiler Production
The food production system needs to be sustainable including poultry sector to feed the increasing global population. An accepted economical and environmental approach of broiler production is to produce larger broilers faster while using less feed. Broiler production is aimed at producing consumable meat and meat products. The global broiler meat market has evolved over the years with increasing selection pressure shifted toward attaining yield characteristics for increased cut-up parts such as breast and thighs. There is a shift toward a big bird market in the U.S. with approximately 70% of the broiler meat produced from large birds (\u3e2.72 kg). Genetic selection of broilers for quantitative traits such as growth rate and lean muscle mass without increasing the fat mass has altered broiler physiological homeostasis to adapt toward the larger rates of muscle protein turnover. Physiological stresses created due to selection pressures in broilers have produced several muscle myopathies including an emerging one called woody breast myopathy. The sustainable broiler production practice may require humane consideration of raising broilers in less stressful grow-out regimes that will have minimal impact on broiler metabolic health. Another sustainability approach of broiler production toward feed efficiency lies on understanding dietary formulation approach of amino acids and energy that promote optimal nutrient utilization and minimal nutrient output to environment while also fulfilling the growth demands and body composition changes associated with increased protein gain in current meat broilers brought by the genetic progress
A novel heuristic for optimization aggregate production problem: Evidence from flat panel display in Malaysia
Link to publisher's homepage at http://scitation.aip.org/This paper contribute to the flat panel display industry it terms of aggregate production planning. Methodology: For the minimization cost of total production of LCD manufacturing, a linear programming was applied. The decision variables are general production costs, additional cost incurred for overtime production, additional cost incurred for subcontracting, inventory carrying cost, backorder costs and adjustments for changes incurred within labour levels. Model has been developed considering a manufacturer having several product types, which the maximum types are N, along a total time period of T. Results: Industrial case study based on Malaysia is presented to test and to validate the developed linear programming model for aggregate production planning. Conclusion: The model development is fit under stable environment conditions. Overall it can be recommended to adapt the proven linear programming model to production planning of Malaysian flat panel display industry
Seasonal changes in physiological and psychological parameters of stress in collegiate swimmers
To investigate the seasonal changes in physiological and psychological parameters of stress in collegiate swimmers. Fifteen NCAA Division I swimmers (8 men) participated in a tethered anaerobic swim test to determine physiological responses in an ecologically-relevant, graded exercise test. Wisconsin Upper Respiratory Symptom Survey (WURSS-21), Activation-Deactivation Adjective Check List (AD-ACL), Daily Analysis of Life Demands of Athletes (DALDA), and Pittsburgh Sleep Quality Index were assessed at post-season in April (V1), the end of off-season in June (V2), and pre-season in October (V3). The percent change was determined from V2–V1 (off-season phase), V3–V2 (pre-season phase), V1–V3 (in-season phase). Spearman’s rho correlation was used to examine associations between change in physiological and psychological outcomes. All data results showed a better swim performance occurred at V2. Men tended to have faster speed (p = 0.07) in fewer strokes (p = 0.10) and greater work per stroke (p = 0.10) at V2 than V1. Women were faster during V2 compared to V1 (p = 0.02) and V3 (p = 0.05). Women had fewer strokes (p = 0.02) and greater work per stroke (p = 0.01) at V2 compared to V3. Women had the lowest HR and lactate concentration at V3 compared to other visits (p \u3c 0.05). During the in-season phase, swim speed decreased the greatest extent and stress sources and symptoms assessed by DALDA had greatest elevation (p \u3c 0.05). An increased in stress sources and symptoms assessed by DALDA was associated with an increase in upper respiratory illness from WURSS-21 (rho = 0.44, p = 0.009), being less energetic (rho = − 0.35, p = 0.04) and greater tension state (rho = 0.49, p = 0.003; AD-ACL), and a decrease in swim speed (rho =− 0.38, p = 0.03). Swim performance peaked at off-season when psychological stress was at its lowest. The relationship between DALDA scores with psychological parameters and swim performance suggested physiological and psychological parameters of stress is an important aspect to avoid overtraining when approaching high swim performance
Tribute to Professor Doug Rendleman
A tribute to Professor Doug Rendleman, who served on the faculty of the Washington and Lee University School of Law from 1988 to 2020. Rendleman became Professor of Law, Emeritus in 2020
Deletion of L-Selectin Increases Atherosclerosis Development in ApoE−/− Mice
Atherosclerosis is an inflammatory disease characterized by accumulation of leukocytes in the arterial intima. Members of the selectin family of adhesion molecules are important mediators of leukocyte extravasation. However, it is unclear whether L-selectin (L-sel) is involved in the pathogenesis of atherosclerosis. In the present study, mice deficient in L-selectin (L-sel−/−) animals were crossed with mice lacking Apolipoprotein E (ApoE−/−). The development of atherosclerosis was analyzed in double-knockout ApoE/L-sel (ApoE−/− L-sel−/−) mice and the corresponding ApoE−/− controls fed either a normal or a high cholesterol diet (HCD). After 6 weeks of HCD, aortic lesions were increased two-fold in ApoE−/− L-sel−/− mice as compared to ApoE−/− controls (2.46%±0.54% vs 1.28%±0.24% of total aortic area; p<0.05). Formation of atherosclerotic lesions was also enhanced in 6-month-old ApoE−/− L-sel−/− animals fed a normal diet (10.45%±2.58% vs 1.87%±0.37%; p<0.05). In contrast, after 12 weeks of HCD, there was no difference in atheroma formation between ApoE−/− L-sel−/− and ApoE−/− mice. Serum cholesterol levels remained unchanged by L-sel deletion. Atherosclerotic plaques did not exhibit any differences in cellular composition assessed by immunohistochemistry for CD68, CD3, CD4, and CD8 in ApoE−/− L-sel−/− as compared to ApoE−/− mice. Leukocyte rolling on lesions in the aorta was similar in ApoE−/− L-sel−/− and ApoE−/− animals. ApoE−/− L-sel−/− mice exhibited reduced size and cellularity of peripheral lymph nodes, increased size of spleen, and increased number of peripheral lymphocytes as compared to ApoE−/− controls. These data indicate that L-sel does not promote atherosclerotic lesion formation and suggest that it rather protects from early atherosclerosis
Defects in Regulation of Local Immune Responses Resulting in Atherosclerosis
Atherosclerosis is nowadays generally accepted as an inflammatory disease
but the mechanism of its origin and development have not yet been fully clarified.
The present review focuses on the role of the local immune system as one of the
key players in the pathogenesis of the complex process. Its part represented by
vascular-associated lymphoid tissue (VALT) within the arterial wall participates
directly in the vascular wall's homeostatis. Its inordinate activation during
ontogenic development of an individual, this formerly defensive and physiologic
mechanism transform into a pathological process resulting in an impairing
inflammation. Hsp60, CRP and oxidized or otherwise modified LDL are serious
candidates for triggering these pathological changes. The principal role is played
by anti-Hsp60 antibodies and by shear stress originating on the surface of
endothelium due to blood flow. The experimental and clinical data
supporting this immunological hypothesis of atherosclerosis are discussed
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
A near-infrared fluorescent probe for fluorine ions and its application in the imaging of HepG2 cells
The capability of capability indices with an application to guardbanding in a test environment
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