A GREEN APPROACH FOR THE SYNTHESIS OF DRUG DELIVERY SYSTEM, MESOPOROUS SILICA GRAFTED ACRYLAMIDE –β- CYCLODEXTRIN COMPOSITE, FOR THE CONTROLLED RELEASE OF CURCUMIN

Objective: The scope of the present study was the preparation and characterization of a novel composite acrylamide β-cyclodextrin grafted 3-aminopropyltriethoxysilane bentonite (AMCD-g-APSB), for the controlled delivery of curcumin (CUR).Methods: AMCD-g-APSB, was synthesized by solvent-free conditions using microwave irradiation. The structure and surface morphology of the composite was established using Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, thermal analysis, etc.Results: The swelling percentage of the composite depends on both time and pH of the medium. The maximum swelling of the composite occurred at a pH of 7.4. The maximum drug encapsulation was occurring at a pH 3. About 96.5% of drug was loaded at pH 3. In vitro biocompatibility study was performed, and the result showed good biocompatibility of the composite in the concentration range 2.5–50 μg/ml.Conclusions: Drug delivery study of the composite proved that CUR could be successfully released in a controlled manner in the colon without much loses of the drug in the stomach

Biochar-ZnO/polyaniline composite in energy storage application: Synthesis, characterization and electrochemical analysis

Carbon materials displaying electrical double layer capacitance are widely used in the electrochemical energy storage devices. To enhance the electrochemical performance, compositing carbon with transition metal oxides and conducting polymers have been very much appreciated. A novel and effective approach to prepare a high energy density and high specific capacitance composite electrode material from a biomass is presented in the work. Pyrolysis of biomass at 500 °C in the nitrogen atmosphere yielded a biochar (BC) with well-developed porosity, surface functionality and suitable morphological characteristics. Anchoring ZnO nanoparticles on BC and subsequently coating it with a conducting polymeric material, polyaniline (PANI) obtained the hierarchical BC-ZnO/PANI composite. Both BC-ZnO and BC-ZnO/PANI composites have been characterized by FTIR, UV–Visible, XRD, SEM and TEM studies. The characteristic signals at 2θ values 18.5°, 28.4°, 24.0° and 31.4° in XRD correspond to wurtzite structure of ZnO nanoparticles. ZnO rod like structural morphology was confirmed by SEM analysis. The maximum specific capacitance was found to be 110.0 F/g for BC-ZnO and 198.0 F/g for BC-ZnO/PANI. The ternary composite displayed low solution resistance and charge transfer resistance as evident from the Nyquist plots. The results proved that PANI coating is a promising methodology in the fabrication of electrode materials for energy storage applications

Banana stem biochar composite with polyaniline for energy storage applications

The production and use of activated carbon from biochar, exclusively for energy storage and environmental applications was attracting attention. In this work, the commonly available banana stem was selected as a precursor to be converted into biochar (BC) at 500℃. The conducting polymer poly aniline (PANI) was then incorporated into the char matrix (BC-PANI) in order to improve the electrical properties. FTIR, UV–visible, XRD, SEM and TEM techniques were used to characterize the polymer composite. The integration PANI onto BC was clearly revealed from SEM and TEM micrographs and also the nanocomposite formation (BC-PANI, 0.37 nm) was confirmed from the XRD analysis. Furthermore, the electrochemical performance was analyzed using cyclicvoltammetry and electrochemical impedance spectroscopy. Both BC and BC-PANI attained maximum specific capacitance of 27.00 and 57.50 Fg−1 respectively. The various resistance that originated at electrode/electrolyte interface was also identified from impedance spectroscopy. These findings highlighted the good capacitive nature of the electrode material (BC-PANI)