37 research outputs found
An investigation of an RFID-based patient-tracking and mobile alert system
Author name used in this publication: S. K. KwokVersion of RecordPublishe
Satellite Cells Senescence in Limb Muscle of Severe Patients with COPD
Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Canada Rationale: The maintenance of peripheral muscle mass may be compromised in chronic obstructive pulmonary disease (COPD) due to premature cellular senescence and exhaustion of the regenerative potential of the muscles. Methods: Vastus lateralis biopsies were obtained from patients with COPD (n = 16) and healthy subjects (n = 7). Satellite cell number and the proportion of central nuclei, as a marker of muscle regenerative events, were assessed on cryosections. Telomere lengths, used as a marker of cellular senescence, were determined using Southern blot analyses. Results: Central nuclei proportion was significantly higher in patients with COPD with a preserved muscle mass compared to controls and patients with COPD with muscle atrophy (p,0.001). In COPD, maximal telomere length was significantly decreased compared to controls (p,0.05). Similarly, minimal telomere length was significantly reduced in GOLD III–IV patients with muscle atrophy compared to controls (p,0.005). Minimal, mean and maximum telomere lengths correlated with mid-thigh muscle cross-sectional area (MTCSA) (R = 0.523, p = 0.005; R = 0.435, p = 0.019 and R = 0.491, p = 0.009, respectively). Conclusions: Evidence of increased regenerative events was seen in GOLD III–IV patients with preserved muscle mass. Shortening of telomeres in GOLD III–IV patients with muscle atrophy is consistent with an increased number of senescen
Numerical simulation of bioaerosol particle exposure assessment in office environment from MVAC systems
2017-2018 > Academic research: refereed > Publication in refereed journal201811 bcmaVersion of RecordPublishe
Ventilation of general hospital wards for mitigating infection risks of three kinds of viruses including Middle East respiratory syndrome coronavirus
Ventilation of General Hospital Wards for Mitigating Infection Risks of three kinds of viruses including Middle East Respiratory Syndrome Coronavirus (MERS-CoV)2015-2016 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptOthersPublic Policy Research Funding Scheme from the Central Policy Unit of the HKSAR Government (Project No. 2014.A6.038.14E)Publishe
Drag constants for common indoor bioaerosols
2014-2015 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptOthersThe Hong Kong Polytechnic University (Project account numbers G-U909 and G-YK22)Publishe
Improving cooling energy efficiency in Hong Kong offices using Demand-Controlled Ventilation (DCV) and Adaptive Comfort Temperature (ACT) systems to provide Indoor Environmental Quality (IEQ) acceptance
202311 bckwAccepted ManuscriptOthersPolyU; HKSAR GovernmentPublishe
Development of a user-friendly Indoor Environmental Quality (IEQ) calculator in air-conditioned offices
9th international Conference on Indoor Air Quality Ventilation & Energy Conservation In Buildings (IAQVEC 2016), 23-26 October 2016, Seoul, South Korea202311 bckwOther VersionSelf-funde
Exhaust ventilation performance in residential washrooms for bioaerosol particle removal after water closet flushing
Accepted ManuscriptRGCOthersRGC: Research Grants Council of the HKSAR, China (PolyU 5272/13E)Others: Public Policy Research Funding Scheme from the Central Policy Unit of the HKSAR Government (Project No. 2014.A6.038.14E)The Hong Kong Polytechnic University (Project Nos. GYBA7, GYM64)Publishe
An experimental study of bioaerosol (1-10 mu m) deposition in a ventilated chamber
2012-2013 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptOthersThe Hong Kong Polytechnic University (Project account numbers G-U909, G-SA04 and YK22)The City University of Hong Kong (Project number 7002273)Publishe