MM-Wave HetNet in 5G and beyond Cellular Networks Reinforcement Learning Method to improve QoS and Exploiting Path Loss Model

This paper presents High density heterogeneous networks (HetNet) which are the most promising technology for the fifth generation (5G) cellular network. Since 5G will be available for a long time, previous generation networking systems will need customization and updates. We examine the merits and drawbacks of legacy and Q-Learning (QL)-based adaptive resource allocation systems. Furthermore, various comparisons between methods and schemes are made for the purpose of evaluating the solutions for future generation. Microwave macro cells are used to enable extra high capacity such as Long-Term Evolution (LTE), eNodeB (eNB), and Multimedia Communications Wireless technology (MC), in which they are most likely to be deployed. This paper also presents four scenarios for 5G mm-Wave implementation, including proposed system architectures. The WL algorithm allocates optimal power to the small cell base station (SBS) to satisfy the minimum necessary capacity of macro cell user equipment (MUEs) and small cell user equipment (SCUEs) in order to provide quality of service (QoS) (SUEs). The challenges with dense HetNet and the massive backhaul traffic they generate are discussed in this study. Finally, a core HetNet design based on clusters is aimed at reducing backhaul traffic. According to our findings, MM-wave HetNet and MEC can be useful in a wide range of applications, including ultra-high data rate and low latency communications in 5G and beyond. We also used the channel model simulator to examine the directional power delay profile with received signal power, path loss, and path loss exponent (PLE) for both LOS and NLOS using uniform linear array (ULA) 2X2 and 64x16 antenna configurations at 38 GHz and 73 GHz mmWave bands for both LOS and NLOS (NYUSIM). The simulation results show the performance of several path loss models in the mmWave and sub-6 GHz bands. The path loss in the close-in (CI) model at mmWave bands is higher than that of open space and two ray path loss models because it considers all shadowing and reflection effects between transmitter and receiver. We also compared the suggested method to existing models like Amiri, Su, Alsobhi, Iqbal, and greedy (non adaptive), and found that it not only enhanced MUE and SUE minimum capacities and reduced BT complexity, but it also established a new minimum QoS threshold. We also talked about 6G researches in the future. When compared to utilizing the dual slope route loss model alone in a hybrid heterogeneous network, our simulation findings show that decoupling is more visible when employing the dual slope path loss model, which enhances system performance in terms of coverage and data rate

Flow-Based Rules Generation for Intrusion Detection System using Machine Learning Approach

Rapid increase in internet users also brought new ways of privacy and security exploitation. Intrusion is one of such attacks in which an authorized user can access system resources and is major concern for cyber security community. Although AV and firewall companies work hard to cope with this kind of attacks and generate signatures for such exploits but still, they are lagging behind badly in this race. This research proposes an approach to ease the task of rules generationby making use of machine learning for this purpose. We used 17 network features to train a random forest classifier and this trained classifier is then translated into rules which can easily be integrated with most commonly used firewalls like snort and suricata etc. This work targets five kind of attacks: brute force, denial of service, HTTP DoS, infiltrate from inside and SSH brute force. Separate rules are generated for each kind of attack. As not every generated rule contributes toward detection that's why an evaluation mechanism is also used which selects the best rule on the basis of precision and f-measure values. Generated rules for some attacks have 100% precision with detection rate of more than 99% which represents effectiveness of this approach on traditional firewalls. As our proposed system translates trained classifier model into set of rules for firewalls so it is not only effective for rules generation but also give machine learning characteristics to traditional firewall to some extent.&nbsp

Anterior Cervical Discectomy and Fusion Surgery: Results with Zero-Profile Spacer/Cage

Objective:  Study provides proof to support the promised benefits of employing stand-alone zero-profile cages in multilevel ACDF procedures, as the stand-alone zero-profile device has proven safety and a reduction of the risk of dysphagia in single-level ACDF surgeries. Materials and Methods:  This is a retrospective descriptive study, conducted at the Punjab Institute of Neurosciences, Lahore, Pakistan. Data of 36 patients evaluated for post-operative dysphagia and fusion, who had multi-level ACDF surgery employing stand-alone zero-profile cages. Results:  Total of 36 patients underwent ACDF surgeries. 86.1% (31/36) patients operated for 2 levels and 13.9% (5/36) patients operated for 3 levels. Dysphagia developed postoperatively in 2 (5.6%) patients in which zero-profile stand-alone cages were used. Fusion was achieved in 94.4% (34/36) patients. Conclusion:  Stand-alone zero-profile cages in multi-level ACDF surgeries have a good outcome in terms of post-operative less dysphagia and higher fusion rates. Keywords:  Anterior Cervical Discectomy (Decompression) And Fusion (ACDF), Zero-Profile Cages, Cervical Spondylotic Myelopathy

Incidence and Surgical Outcome of the Intracranial Epidermoid Cyst at Punjab Institute of Neurosciences Lahore, Pakistan

Objectives:  The incidence and microsurgical outcomes of intracranial epidermoid cysts in the Department of Neurosurgery III, Punjab Institute of Neurosciences (PINS), Lahore, Pakistan, are described in this case series. Materials and Methods:  This study was a data analysis of a case series of 15 patients (mean age, 40 years) of both gender with intracranial epidermoid cysts who had microsurgical surgical excision over five years. Results:  This study comprised 11 (73.3%) male and 4 (26.7%) female patients, 11 (73.3%) cases were infratentorial and 4 (26.7%) cases were in supratentorial region. The epidermoid was located in the CP angle in 11 (73.3%) patients, 3 (20%) in the midline supra sellar region, and 1 (6.66%) in the frontotemporal region. The presenting complaints were mainly headache in 11 (73.33%), cranial nerve palsy and cerebellar signs in 8 (53.3%) patients, Trigeminal neuralgia in 3 (20%) patients, Fits and hydrocephalus in 2 (13.3%) patients. There were 14 (93.3%) patients with GTR (gross total resection), 1 (6.6%) patients STR (subtotal resection). According to Karnofsky's performance scoring (KPS), 3 (20%) patients improved, 11 (73.3%) patients had the same KPS, and 1 (6.6%) patient had a lower KPS. Conclusion:  The epidermoid cysts in the brain are usually found in the infratentorial region rather than the supratentorial region. Infratentorial lesions typically cause cranial nerve deficits, whereas the supratentorial area symptom is a headache

Improved MRO inventory management system in oil and gas company : increased service level and reduced average inventory investment

This study proposes a methodology for the oil and gas businesses to keep their production plant productive with a minimum investment in carrying maintenance, repair, and operating inventory planning. The goal is to assist the exploration and production companies in minimizing the investment in keeping maintenance, repair, and operating (MRO) inventory for improving production plant uptime. The MRO inventory is the most expensive asset and it requires substantial investment. It helps in keeping the oil and gas production plant productive by performing planned and unplanned maintenance activities. A (Q, r) model with a stock-out and backorder cost approach is combined with a continuous inventory review policy for the analysis of class A items of oil and gas production plant MRO inventory. The class A items are identified through popular ABC analysis based on annual dollar volume. The demand for the inventory is modeled through Poisson distribution with consideration of constant lead time. The (Q, r) model in both stock-out cost and backorder cost approaches assigned higher order frequency and lower service level to low annual demand and highly expensive items. The stock-out cost approach shows an 8.88% increase in the average service level and a 56.9% decrease in the company average inventory investment. The backorder cost approach results in a 7.77% increase in average service level and a 57% decrease in average inventory investment in contrast to the company’s existing inventory management system. The results have a direct impact on increasing plant uptime and productivity and reducing company maintenance cost through properly managing maintenance stock. The analysis is carried out on the oil and gas production plant’s MRO inventory data, but it can be applied to other companies’ inventory data as well. All the results reflected in this research are based on the inventory ordering policy of two orders per year. The inventory ordering frequency per year may be other than two orders per year depending on the type of organization

Ten years risk assessment of atherosclerotic cardiovascular disease using Astro-CHARM and pooled cohort equation in a south Asian sub-population

Background: Atherosclerotic cardiovascular diseases (ASCVD) are on the rise in low and middle-income countries attributed to modern sedentary lifestyle and dietary habits. This has led to the need of assessment of the burden of at-risk population so that prevention measures can be developed. The objective of this study was to assess ten years risk assessment of ASCVD using Astro-CHARM and Pooled Cohort Equation (PCE) in a South Asian sub-population.Methods: A total of 386 residents of all six districts of Karachi with no ASCVD were enrolled in the study through an exponential non-discriminative referral snowball sampling technique. The inclusion criteria consisted of age 40 years or above and either gender. Study participants were enrolled after obtaining informed written consent and those study participants who were found to have either congenital heart disease or valvular heart diseases or ischemic heart disease were excluded from the study based on initial screening. For the calculation of 10 years risk of ACVD based on Astro-CHARM and PCE, the variables were obtained including medical history and coronary artery calcium and C-reactive protein measurements.Results: Mean estimated 10-year risk of fatal or non-fatal myocardial infarction or stroke as per the Astro-CHARM was 13.98 ± 8.01%, while mean estimated 10-year risk of fatal or non-fatal myocardial infarction or stroke as per the PCE was 22.26 ± 14.01%. Based on Astro-CHARM, 11.14% of the study participants were labeled as having high risk, while PCE estimated 20.73% of study participants as having high risk of ASCVD.Conclusion: Despite the fact that our findings showed substantial differences in ten-year risk of ASCVD between Astro-CHARM and PCE, both calculators can be used to develop a new population and specific risk estimators for this South Asian sub-population. Our study provides the first step towards developing a risk assessment guided decision-making protocol for primary prevention of ASCVD in this population

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020

Trading Algorithm Model Based on Technical Indicators

Today the rapid proliferation of the internet provides an environment where efficient e-commerce solutions can be developed. The electronic market is gaining more attention in the global economy, it gives buyers and sellers more liberty to trade cost-effectively and allows access to an adequate amount of data for analysis. New trading agents have been developed for the best utilization of such data. These agents design strategies using financial analysis techniques such as technical indicators. Two very well-known technical indicators used to develop strategies are Convergence-Divergence (MACD) and Stochastic Oscillator (SO). This paper aims to devise a trading algorithm that combines MACD and SO in a single strategy and check the reliability of the combined signals it generates. JTAP simulation system has been used to test the proposed strategy. In this paper, we evaluated the performance of our proposed strategy when implemented on shares of Karachi Stock Exchange, Pakistan which proves improvement of strategy

Outcomes of Acromegaly Patients Treated with Sandostatin LAR after Surgical Excision of Pituitary Adenoma

Objectives:  An observational study to evaluate the outcomes of Acromegaly patients treated in the department of Neurosurgery III, Punjab Institute of Neurosciences (PINS), Lahore, Pakistan. Materials and Methods:  This study was the analysis of a case series of 20 patients (mean age: 30 years) of both genders with acromegaly due to macroadenoma who had endonasal excision and postoperative treatment with Sandostatin LAR. Results:  This study consisted of a total of 20 patients out of which 11 (55%) were male and 9 (45%) were female. All 20 Patients (100%) had a headache as their main symptom and 13 patients (65%) had visual field deterioration. 19 patients (95%) had complete resection of the tumor whereas 1 (5%) had a subtotal resection. After surgery and treatment growth hormone levels improved in 19 patients (95%) and remained elevated in 1 patient (5%), IGF-1 (Insulin-like growth factor – 1) levels improved in all 20 (100%) patients. Following consecutive octreotide injections vision of 11 patients (84%) out of 13 improved and in 2 (16%) patients, it remained the same as of Preoperative status whereas Headache improved in all 20 (100%) of the patients. None of the patients had any complications related to the procedure or the injection of octreotide LAR. Conclusion:  Acromegaly due to macroadenoma responds well to treatment with octreotide LAR after endonasal resection in terms of hormonal levels and symptoms of the patients. It is a safe treatment with very less side effects and complications

Percutaneous pedicle screw fixation

Percutaneous pedicle screw fixation (PSF) has emerged as a promising alternative to traditional open surgical approaches for spinal stabilization. Pedicle screws are inserted through percutaneous access sites without substantial soft tissue dissection. To ensure proper screw insertion, the procedure employs fluoroscopic or image-guided navigation devices. The popularity of percutaneous PSF has accelerated because of its prospective advantages and the mounting body of research demonstrating its effectiveness and safety. However, there are a few drawbacks to the procedure, such as a longer learning curve for surgeons, poor visibility when inserting screws, and a requirement for specialized tools and imaging guiding systems. This article provides a comprehensive review of the technique of percutaneous PSF, its clinical outcomes, and recent advancements in the field. It also aims to analyze the efficacy, safety, and limitations of percutaneous PSF, as well as explore the evolving technologies and techniques that have contributed to its improved application