A minimum hypothesis explanation for an IMF with a lognormal body and power law tail

We present a minimum hypothesis model for an IMF that resembles a lognormal distribution at low masses but has a distinct power-law tail. Even if the central limit theorem ensures a lognormal distribution of condensation masses at birth, a power-law tail in the distribution arises due to accretion from the ambient cloud, coupled with a non-uniform (exponential) distribution of accretion times.Comment: 2 pages, 1 figure, to appear in IMF@50, eds. E. Corbelli, F. Palla, and H. Zinnecker, Kluwer, Astrophysics and Space Science Librar

The Nature of the Dense Core Population in the Pipe Nebula: Thermal Cores Under Pressure

In this paper we present the results of a systematic investigation of an entire population of starless dust cores within a single molecular cloud. Analysis of extinction data shows the cores to be dense objects characterized by a narrow range of density. Analysis of C18O and NH3 molecular-line observations reveals very narrow lines. The non-thermal velocity dispersions measured in both these tracers are found to be subsonic for the large majority of the cores and show no correlation with core mass (or size). Thermal pressure is thus the dominate source of internal gas pressure and support for most of the core population. The total internal gas pressures of the cores are found to be roughly independent of core mass over the entire range of the core mass function (CMF) indicating that the cores are in pressure equilibrium with an external source of pressure. This external pressure is most likely provided by the weight of the surrounding Pipe cloud within which the cores are embedded. Most of the cores appear to be pressure confined, gravitationally unbound entities whose nature, structure and future evolution are determined by only a few physical factors which include self-gravity, the fundamental processes of thermal physics and the simple requirement of pressure equilibrium with the surrounding environment. The observed core properties likely constitute the initial conditions for star formation in dense gas. The entire core population is found to be characterized by a single critical Bonnor-Ebert mass. This mass coincides with the characteristic mass of the Pipe CMF indicating that most cores formed in the cloud are near critical stability. This suggests that the mass function of cores (and the IMF) has its origin in the physical process of thermal fragmentation in a pressurized medium.Comment: To appear in the Astrophysical Journa

The ADS All-Sky Survey

The ADS All-Sky Survey (ADSASS) is an ongoing effort aimed at turning the NASA Astrophysics Data System (ADS), widely known for its unrivaled value as a literature resource for astronomers, into a data resource. The ADS is not a data repository per se, but it implicitly contains valuable holdings of astronomical data, in the form of images, tables and object references contained within articles. The objective of the ADSASS effort is to extract these data and make them discoverable and available through existing data viewers. The resulting ADSASS data layer promises to greatly enhance workflows and enable new research by tying astronomical literature and data assets into one resource.Astronom

Substrate polyspecificity and conformational relevance in ABC transporters: new insights from structural studies

Transport of molecules and ions across biological membranes is an essential process in all organisms. It is carried out by a range of evolutionarily conserved primary and secondary transporters. A significant portion of the primary transporters belong to the ATP-binding cassette (ABC) superfamily, which utilise the free-energy from ATP hydrolysis to shuttle many different substrates across various biological membranes, and consequently, are involved in both normal and abnormal physiology. In humans, ABC transporter-associated pathologies are perhaps best exemplified by multidrug-resistance transporters that efflux many xenobiotic compounds due to their remarkable substrate polyspecificity. Accordingly, understanding the transport mechanism(s) is of great significance, and indeed, much progress has been made in recent years, particularly from structural studies on ABC exporters. Consequently, the general mechanism of 'alternate access' has been modified to describe individual transporter nuances, though some aspects of the transport process remain unclear. Moreover, as new information has emerged, the physiological relevance of the 'open-apo' conformation of MsbA (a bacterial exporter) has been questioned and, by extension, its contribution to mechanistic models. We present here a comprehensive overview of the most recently solved structures of ABC exporters, focusing on new insights regarding the nature of substrate polyspecificity and the physiological relevance of the 'open-apo' conformation. This review evaluates the claim that the latter may be an artefact of detergent solubilisation, and we hypothesise that the biophysical properties of the membrane play a key role in the function of ABC exporters allowing them to behave like a 'spring-hinge' during their transport cycle

Embedded Clusters and the IMF

Despite valiant efforts over nearly five decades, attempts to determine the IMF over a complete mass range for galactic field stars and in open clusters have proved difficult. Infrared imaging observations of extremely young embedded clusters coupled with Monte Carlo modeling of their luminosity functions are improving this situation and providing important new contributions to our fundamental knowledge of the IMF and its universality in both space and time.Comment: 6 pages, 2 figures to appear in "The IMF@50", Kluwer Academic Press, eds. C. Corbelli, F. Palla, & Hans Zinnecke